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In this issue

Review Article

  1. Review ArticlePublished: 18 Mar 2013

    Steffy B Manjila, Jomon N Baby, Elambilan N Bijin, Icey Constantine, Kannissery Pramod, Janardhanan Valsalakumari

    pp. 1-7 · DOI: 10.4103/2230-973X.108958Vol. 3, Issue 1 (2013)

    Gene therapy is an emerging field in medical and pharmaceutical sciences because of its potential in treating chronic diseases like cancer, viral infections, myocardial infarctions, and genetic disorders. Application of …

  2. Review ArticlePublished: 18 Mar 2013

    Amit Goel, Sanjula Baboota, Jasjeet K Sahni, Javed Ali

    pp. 8-14 · DOI: 10.4103/2230-973X.108959Vol. 3, Issue 1 (2013)

    Lung cancer is the most malignant cancer today. The treatment of lung cancer continues to be a challenge for oncologists. The direct delivery of chemotherapeutic agents to the lungs could represent a novel therapeutic ap…

Original Research Article

  1. Original Research ArticlePublished: 18 Mar 2013

    Amit Mukharya, Paresh U Patel, Dinesh Shenoy, Shivang Chaudhary

    pp. 15-28 · DOI: 10.4103/2230-973X.108960Vol. 3, Issue 1 (2013)

    Introduction: Lacidipine (LCDP) is a very low soluble and highly biovariable calcium channel blocker used in the treatment of hypertension. To increase its apparent solubility and to reduce its biovariability, solid disp…

  2. Original Research ArticlePublished: 18 Mar 2013

    Kevin Garala, Parth Joshi, Malay Shah, A Ramkishan, Jaydeep Patel

    pp. 29-41 · DOI: 10.4103/2230-973X.108961Vol. 3, Issue 1 (2013)

    Background: The present study was aimed to develop and optimize in situ gel for the treatment of periodontal disease. Materials and Methods: Temperature‑sensitive in situ gel containing 0.1% w/v Chlorhexidine hydrochlori…

  3. Original Research ArticlePublished: 18 Mar 2013

    Raj Kaur Malik, Prashant Malik, Neha Gulati, Upendra Nagaich

    pp. 42-46 · DOI: 10.4103/2230-973X.108962Vol. 3, Issue 1 (2013)

    Background: Mucoadhesive beads were fabricated and evaluated for controlled release of an antiemetic drug ‘Ondansetron Hydrochloride’. Ondansetron hydrochloride is a serotonin 5‑HT3 receptor antagonist mainly used for th…

  4. Original Research ArticlePublished: 18 Mar 2013

    Mohasin Lodhi, Akhilesh Dubey, Reema Narayan, Prabhakara Prabhu, Sneh Priya

    pp. 47-53 · DOI: 10.4103/2230-973X.108963Vol. 3, Issue 1 (2013)

    Background: Ivabradine hydrochloride is an anti‑anginal drug with a biological half‑life of about 2 h, and repeated daily administration is needed to maintain effective plasma level. Present investigation of buccal films…

  5. Original Research ArticlePublished: 18 Mar 2013

    Abdul Wadood Khan, Sabna Kotta, Sudha Rana, Shahid Husain Ansari, Rakesh Kumar Sharma, Javed Ali

    pp. 54-59 · DOI: 10.4103/2230-973X.108964Vol. 3, Issue 1 (2013)

    Background: Increased use of the radioactive materials in the field of research, medical, nuclear power plant, and industry has increased the risk of accidental exposure. Intentional use of the radioisotopes by terrorist…

  6. Original Research ArticlePublished: 18 Mar 2013

    Vikas Mathur, Kalpana Nagpal, Shailendra Kumar Singh, Dina Nath Mishra

    pp. 60-65 · DOI: 10.4103/2230-973X.108965Vol. 3, Issue 1 (2013)

    Introduction: Verapamil hydrochloride (VH) is a calcium channel blocking agent used in the treatment of hypertension, cardiac arrhythmia and angina pectoris. The short half‑life and high frequency of administration of VH…