International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 38Review Article
Review ArticlePublished: 2 Apr 2024
Sai Madhav Peddibhotla, Aishwarya Nair, Anju Joby
pp. 268-272 · DOI: 10.5530/ijpi.14.2.34Vol. 14, Issue 2 (2024)Halotherapy is the use of dehumidified oxygen or salt aerosol microparticles attached to a face to treat pulmonary conditions. It was first reported as a substitute to oxygen masks for speleotherapy, a healing technique …
Review ArticlePublished: 2 Apr 2024
Sarojini Nayak, Druga Madhab Kar, Saroj Kumar Choudhury, Manoj Kumar Dalai
pp. 273-288 · DOI: 10.5530/ijpi.14.2.35Vol. 14, Issue 2 (2024)Polygonum plebeium R. Br. (Family: Polygonaceae) is commonly known as “small knotweed”. It is used as a traditional medicine by many cultures across the world. In the rural communities of Shahjahanpur, Uttar Pradesh, it …
Review ArticlePublished: 2 Apr 2024
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, B J Abhishek, Leena Elizabeth Varghese, S K Bhoomika
pp. 289-298 · DOI: 10.5530/ijpi.14.2.36Vol. 14, Issue 2 (2024)This review explores the evolution of the concept of Healthcare-Associated Pneumonia (HCAP) in light of the 2016 guidelines from the Infectious Diseases Society of America (IDSA). These updated guidelines prioritize pati…
Review ArticlePublished: 2 Apr 2024
Sonal Jesa Dsouza, DS Sandeep, R Narayana Charyulu, MP Gowrav, HK Pradeep
pp. 299-305 · DOI: 10.5530/ijpi.14.2.37Vol. 14, Issue 2 (2024)Impurities are undesired chemical substances found in pharmaceutical drug products with no therapeutic benefits and, in some cases, can pose a risk to patient safety if their levels exceed a certain limit. Impurities pre…
Review ArticlePublished: 2 Apr 2024
Varadarajan Sathiya, V Ramesh Kumar
pp. 306-316 · DOI: 10.5530/ijpi.14.2.38Vol. 14, Issue 2 (2024)Studying the immunogenicity of insulin is crucial for managing and treating diabetes and other medical conditions. Although insulin therapy is proven effective for diabetic patients, the presence of insulin antibodies ca…
Review ArticlePublished: 2 Apr 2024
Gopinath Subramaniyan, Shaik Rubina, Bachu Venkata Ramana, A. Meriton Stanley, Devasena Srinivasan
pp. 317-326 · DOI: 10.5530/ijpi.14.2.39Vol. 14, Issue 2 (2024)Background: The growing popularity of transdermal patches is attributed to their advantageous characteristics, including the absence of gastric-related problems, prolonged drug release, enhanced safety and stability, and…
Review ArticlePublished: 2 Apr 2024
Vaibhav Rastogi, Mayur Porwal, Anurag Verma, Umair Khan, Prabal Chauhan, Prashant Kumar
pp. 327-337 · DOI: 10.5530/ijpi.14.2.40Vol. 14, Issue 2 (2024)Recurrent Aphthous Stomatitis (RAS) is a condition characterized by the development of ulcers and lesions, in the mouth. It affects a wide portion of the population ranging from 5% to 25%. RAS more commonly affects labia…
Review ArticlePublished: 2 Apr 2024
B. Kishore Babu
pp. 338-342 · DOI: 10.5530/ijpi.14.2.41Vol. 14, Issue 2 (2024)Personalized medicine, driven by advancements in pharmacology, is revolutionizing healthcare by tailoring medical treatments to the unique characteristics of individual patients. This paradigm shift from a generalized ap…
Original Article
Original ArticlePublished: 2 Apr 2024
Ashwini Somayaji, Chakrakodi Shashidara Shastry
pp. 343-349 · DOI: 10.5530/ijpi.14.2.42Vol. 14, Issue 2 (2024)Objectives: The purpose of this study was to assess the potential synergistic and chemo sensitizing effects of the plant-derived flavonoid EGCG (Epigallocatechin gallate) as an adjuvant therapy with doxorubicin in combat…
Original ArticlePublished: 2 Apr 2024
Rohit Jaysing Bhor, Wayse Siddheshwar Sunil, Rahul Bapusaheb Shirole, Karan Suresh Kadam, Santosh Dighe, Mahesh Hari Kolhe
pp. 350-358 · DOI: 10.5530/ijpi.14.2.43Vol. 14, Issue 2 (2024)Background: A heterocyclic hydrocarbon having a 5, 5-diphenylimidazolidine heterocyclic ring that possesses distinctive fundamental structural characteristics. It is a fused ring of aromatic di-benzene and imidazolidine.…
Original ArticlePublished: 2 Apr 2024
Farzana Sadaf, Sumbul Shamim, Humera Ishaq, Ata-ur- Rehman, Ishrat Younus, Faheema Siddiqui
pp. 359-364 · DOI: 10.5530/ijpi.14.2.44Vol. 14, Issue 2 (2024)Background: High Blood Pressure (BP) is a dreadful condition worldwide. Available scientific data confirms the antihypertensive potential of traditional plants. Present study was aimed to assess the blood pressure loweri…
Original ArticlePublished: 2 Apr 2024
Navid Naghsh, Shiva Barnoos, Fatemeh Zisti, Kethineni Chandrika, Davoud Balarak
pp. 365-370 · DOI: 10.5530/ijpi.14.2.45Vol. 14, Issue 2 (2024)Background: The development of micro-organism resistance in humans and the environment has been linked to the inadequacy of conventional treatment methods in completely eliminating antibiotics. The purpose of this resear…
Original ArticlePublished: 2 Apr 2024
Sk. Mehatab Unnisa, Sana Seereen, Jampana Lekhana, Goreti Archana, Annam Hemanth Kumar, Soma Mani Santhosh Nikhil, Maram Chinnaeswraiah
pp. 371-377 · DOI: 10.5530/ijpi.14.2.46Vol. 14, Issue 2 (2024)Background: The most prevalent lifestyle diseases are Diabetes Mellitus type 2 (DM2) and Hypertension (HTN), especially in older age groups, which leads to Chronic Kidney Disease (CKD) as the most possible comorbidity. M…
Original ArticlePublished: 2 Apr 2024
Rajesh Hadia, Nishee Chhatbar, Priyanka Padiya, Viram Shah, Siddhi Patel, Neel Shah, Hemraj Singh Rajput
pp. 378-385 · DOI: 10.5530/ijpi.14.2.47Vol. 14, Issue 2 (2024)Background: Ureteric stones, characterized by the crystallization of mineral particles in stagnant urine, cause considerable discomfort and pain. Alpha-blockers are employed in the management of ureteric stones to allevi…
Original ArticlePublished: 2 Apr 2024
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Akshata M Purantar, Bibi Khuteja Jangliwale, Kaushal Kumar, T. P Rakshitha
pp. 386-391 · DOI: 10.5530/ijpi.14.2.48Vol. 14, Issue 2 (2024)Background: Geriatric populations have at high probability of getting drug-related issues due to age-related pharmacokinetic and pharmacodynamic changes. Ageing populations are more prone to have DRPs due to age, drug ch…
Original ArticlePublished: 2 Apr 2024
Hezinglila Grace, D. Leelavathi, Kevizano Jacinta Zashumo
pp. 392-398 · DOI: 10.5530/ijpi.14.2.49Vol. 14, Issue 2 (2024)Background: Staphylococcus aureus is an adaptive and versatile microorganism that can cause a wide range of ailments, from intense and short-lived infections to persistent infections that are difficult to cure. Even thou…
Original ArticlePublished: 2 Apr 2024
Devyani Rajput, Dharmendra Jain, Sushil Kumar Kashaw, Umesh Kumar Patil
pp. 399-408 · DOI: 10.5530/ijpi.14.2.50Vol. 14, Issue 2 (2024)Background: Nyctanthes arbortristis Linn., popularly referred to as Parijat or Night-flowering Jasmine, has garnered significant attention in traditional medicinal practices owing to its wide-ranging array of phytochemic…
Original ArticlePublished: 2 Apr 2024
Duyu Taaza, Sunil S. Jalalpure, Basanagouda M. Patil, Bhaskar Kurangi
pp. 409-418 · DOI: 10.5530/ijpi.14.2.51Vol. 14, Issue 2 (2024)Background: Olanzapine causes alterations in lipid and glucose metabolism, indicated by weight gain, and altered metabolic profiles. Hesperidin has been related to numerous positive health benefits including improvements…
Original ArticlePublished: 2 Apr 2024
M Ashwini, K P Kiran, Mamun Ahmed, A P Ravinandan, G Mohammed Mustafa
pp. 419-427 · DOI: 10.5530/ijpi.14.2.52Vol. 14, Issue 2 (2024)Background: Clinical Pharmacy Services (CPSs) is a branch of health sciences which render patient care by optimizing pharmaceutical therapy and providing guidance to patient regarding health, medications and disease prev…
Original ArticlePublished: 2 Apr 2024
Nimmathota Madhavi, Balaga Divya, Beeravelli Sudhakar, Tadikonda Rama Rao
pp. 428-435 · DOI: 10.5530/ijpi.14.2.53Vol. 14, Issue 2 (2024)Background: Mesalamine produces many side effects through oral route such as stomach cramps, throat irritation, back ache and muscle pain. Furthermore, it failed to yield maximum drug release and also not able to produce…