International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 31Review Article
Review ArticlePublished: 2 Oct 2020
Amit Chivate, Atul Garkal, Namdev Dhas, Tejal Mehta
pp. 233-236 · DOI: 10.5530/ijpi.2020.3.43Vol. 10, Issue 3 (2020)The three-dimensional printing is a growing field in engineering, civil constructions and pharmaceutical development. The three-dimensional printing is a one-step continuous process. However, conventional manufacturing i…
Review ArticlePublished: 2 Oct 2020
Kuralla Hari, Sunkara Sai Prathyusha, Gokavarapu Vasavi
pp. 237-245 · DOI: 10.5530/ijpi.2020.3.44Vol. 10, Issue 3 (2020)Colon Targeted Oral Drug Delivery System has gained much importance in recent times in delivering drug substance for the local action against colonic cancers, infections, Ulcerative Colitis (UC) and Crohn’s disease and f…
Review ArticlePublished: 2 Oct 2020
Puneeth Jayram, Preethi Sudheer
pp. 246-252 · DOI: 10.5530/ijpi.2020.3.45Vol. 10, Issue 3 (2020)Low aqueous solubility and concomitant oral bioavailability are the major glitches found in converting the active pharmaceutical ingredients to new pharmaceutical products. Many methods are in existence to improve the so…
Review ArticlePublished: 2 Oct 2020
Nanostructured Lipid Carriers (NLC): A Targeting Approach to the Brain via Intranasal Administration
Swatantra Kumar Singh Kushwaha, Neelottama Kushwaha, Bushra Fatma, Piyush Pandey
pp. 253-256 · DOI: 10.5530/ijpi.2020.3.46Vol. 10, Issue 3 (2020)Different barriers like a blood-brain barrier in the brain restrict the transport of potential therapeutic elements for direct entry into the brain. For delivery of a wide range of therapeutic drugs directly to the brain…
Review ArticlePublished: 2 Oct 2020
Mourya Mamtashanti, Jadav Rahul, Thummar Kashyap
pp. 257-262 · DOI: 10.5530/ijpi.2020.3.47Vol. 10, Issue 3 (2020)Counterfeit drugs are a serious issue nowadays, which has been burdening for developing countries and has a significant impact on the health of people. The Indian drug regulatory agency has published the details of the c…
Review ArticlePublished: 2 Oct 2020
Reshma Pushpa Murali, Lovely Joylen Castelino, Ravi Gundadka Shriram, Akhilesh Dubey
pp. 263-267 · DOI: 10.5530/ijpi.2020.3.48Vol. 10, Issue 3 (2020)Stability studies form a crucial aspect of the pharmaceutical development process and play a vital role in establishing the quality, safety and efficacy of the drug product. The core objective of a stability study is to …
Original Article
Original ArticlePublished: 2 Oct 2020
Vinay Kumar Srivastava
pp. 268-272 · DOI: 10.5530/ijpi.2020.3.49Vol. 10, Issue 3 (2020)Objectives: Schiff base ligand 2-thio phenyl glyoxal anthranilic acid is used as the starting material for the synthesis of many biologically active compounds. The main objectives of the Study was to synthesize, characte…
Original ArticlePublished: 2 Oct 2020
Vemula Vani, Jayashree D J, Navya K S, Akanchha A, Syeda Tanzeela Zaman
pp. 273-278 · DOI: 10.5530/ijpi.2020.3.50Vol. 10, Issue 3 (2020)Introduction: Laccases are phenol oxidases which belong to the superfamily of multicopper oxidases. Laccases are found in almost all wood-rotting fungi. There is evidence that laccases can play an important role in ligni…
Original ArticlePublished: 2 Oct 2020
Subramanaian Rajarajan, B Prakash Rao, S Selvamuthukumar
pp. 279-285 · DOI: 10.5530/ijpi.2020.3.51Vol. 10, Issue 3 (2020)Objectives: The present systematic research is to design, develop clarithromycin nasal mucoadhesive microspheres for the utilisation in respiratory tract infection as alternative route of drug delivery. Methods: Current …
Original ArticlePublished: 2 Oct 2020
Sharada L Deore, Bhushan A Baviskar, Anjali Kide, Ashwin D Deshmukh, Yogita B Khandare, Ramdas B Rode
pp. 286-293 · DOI: 10.5530/ijpi.2020.3.52Vol. 10, Issue 3 (2020)Introduction: Present study is focused to develop micro emulsion based nasal formulation of poorly water soluble antipsychotic/anti-schizophrenic drug Aripiprazole. Materials and Methods: Different surfactants and co sur…
Original ArticlePublished: 2 Oct 2020
Syed Iftequar Ahmed, Zahid Zaheer, Furquan Nazimuddin Khan, Moizul Hasan
pp. 294-299 · DOI: 10.5530/ijpi.2020.3.53Vol. 10, Issue 3 (2020)Objectives: A sustained release Gastro-bilayer floating tablets with reduced dosing frequency and increased drug bioavailability is developed. The dosage form is suitable for the release of two drugs simultaneously in a …
Original ArticlePublished: 2 Oct 2020
Mohammad Ali Daneshmehr, Hilda Adibpour, Zahra Ataie
pp. 300-304 · DOI: 10.5530/ijpi.2020.3.54Vol. 10, Issue 3 (2020)Background: The present study involves the formulation and in-vitro assessment of mucoadhesive tablets of hydrocortisone sodium succinate. Local treatment for buccal inflammatory injuries such as aphthous wounds relies o…
Original ArticlePublished: 2 Oct 2020
Sushant Kumar, Nookala Venkala Satheesh Madhav, Anurag Verma, Kamla Pathak
pp. 305-311 · DOI: 10.5530/ijpi.2020.3.55Vol. 10, Issue 3 (2020)Objectives: The bionanosuspension was prepared by using the isolated biopolymer from Fragaria ananassa fruit which serve as a potential, natural polymeric nature biomaterial. The isolated biomaterial was used for the pre…
Original ArticlePublished: 2 Oct 2020
Kadam Sneha D, Shinde Sarika P, Chavan Tejonmayi S, Phatake Yogesh B, Mane Sneha G, Dhawan Shivanjali S, Marathe Rajendra J, Deshmukh Rajkumar B, Dharmadhikari Smita M
pp. 312-319 · DOI: 10.5530/ijpi.2020.3.56Vol. 10, Issue 3 (2020)Objectives: In this study, silver nanoparticles (AgNPs) were synthesized using healthy plant parts like fruits, stem and leaves of Ficus racemosa. Methods: The collected plant samples were processed by cleaning, drying a…
Original ArticlePublished: 2 Oct 2020
Rupali Kale, Dattatray Doifode, Pratiksha Shete
pp. 320-325 · DOI: 10.5530/ijpi.2020.3.57Vol. 10, Issue 3 (2020)Background: Bacterial infections at wound site are one of the major causes for delayed healing. The aim of this study was to develop topical film forming spray having Combination of Simvastatin and Mupirocin which can av…
Original ArticlePublished: 2 Oct 2020
Azza Ali Hasan, Rasha Mohamed Samir, Samir Sayed Abu-Zaid, Amr Selim Abu Lila
pp. 326-331 · DOI: 10.5530/ijpi.2020.3.58Vol. 10, Issue 3 (2020)Objective: Mebeverine hydrochloride is an antispasmodic agent that has a direct musculotropic action on the smooth muscles of the gastrointestinal tract; especially the colon.Therefore, the current study aimed at formula…
Original ArticlePublished: 2 Oct 2020
Priya Patel, Mihir Raval, Navin Sheth
pp. 332-338 · DOI: 10.5530/ijpi.2020.3.59Vol. 10, Issue 3 (2020)Background: Solid lipid nanoparticles are rapidly developing field of nanotechnology with several potential applications in drug delivery with spherical shape and an average diameter between 1 and 1000 nm. Due to their s…
Original ArticlePublished: 2 Oct 2020
Davoud Balarak, Marzieh Baniasadi, Maryam Bazzi, Kethineni Chandrika
pp. 339-343 · DOI: 10.5530/ijpi.2020.3.60Vol. 10, Issue 3 (2020)Objectives: Today, due to increasing usage of antibiotics and their destructive effects on health and environment, it is necessary to remove them from receiving waters. Although there are few studies on the use of magnet…
Original ArticlePublished: 2 Oct 2020
Rahul Ravindra Padalkar, Ashwini Raghavendra Madgulkar, Mangesh Ramesh Bhalekar
pp. 344-350 · DOI: 10.5530/ijpi.2020.3.61Vol. 10, Issue 3 (2020)Objectives: The objective of this work was to enhance the bioavailability of rizatriptan for brain targeted drug delivery through glutathione conjugated liposomes. Methods: Cholesterol glutathione conjugate was synthesiz…
Original ArticlePublished: 2 Oct 2020
Monica Chang Chuong, Pornpawit Suriyamongkol, Ria Vashishth, Ayushi Saxena, Charles Kelley
pp. 351-356 · DOI: 10.5530/ijpi.2020.3.62Vol. 10, Issue 3 (2020)Objectives: Porous silicon materials were first reported to be biocompatible in 1995. This project employed the evaluation of whether diclofenac sodium is acid labile or acid insoluble. Second, literature only reported 1…