International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Review ArticlePublished: 1 Jul 2021
Satish Arunrao Polshettiwar, Chinmay Devidas Deshmukh, Akshay Motilal Baheti, Manish Shivdas Wani, Ekta Bompilwar, Devashree Jambhekar, Shradha Choudhari, Amol Tagalpallewar
pp. 131-136 · DOI: 10.5530/ijpi.2021.2.25Vol. 11, Issue 2 (2021)A biosensor provides a strategy for the detection of microbiological signals through various chemical, biological and physical technology and is an analytical, high-sensitivity rapid tool in pharmaceutical and health car…
Review ArticlePublished: 1 Jul 2021
SND Balakrishna Ch, Sai Pavan Dwarapudi, Ravi Kumar Reddy Juturi, Venkateswara Raju K.
pp. 137-142 · DOI: 10.5530/ijpi.2021.2.26Vol. 11, Issue 2 (2021)Expedited approval processes push new drugs to the market faster than ever. Regulatory Authorities of the United States (US) and European Union (EU) are using different approval pathways to cut down the time it takes to …
Meta Analysis
Meta AnalysisPublished: 1 Jul 2021
B.M. Gupta, S.M. Dhawan, K.K. Mueen Ahmed, Ghouse Modin Mamdapur
pp. 143-153 · DOI: 10.5530/ijpi.2021.2.27Vol. 11, Issue 2 (2021)The paper describes quantitative and qualitative dimensions of nanomedicine research studies in India. The study is based on research publications data in nanomedicine research (1491 publications) as covered in Scopus da…
Original Article
Original ArticlePublished: 1 Jul 2021
Rosaline Mishra, Divya Juyal, Sadish Kumar Shanmugham
pp. 154-157 · DOI: 10.5530/ijpi.2021.2.28Vol. 11, Issue 2 (2021)Objectives: It is well established fact that the phytochemicals with phenolic and flavonoids origin have antioxidant property. Thus in this study it was aimed to determine the in vitro antioxidant potential of various ex…
Original ArticlePublished: 1 Jul 2021
Satyanarayana Murthy Malladi, Nagendra Sastry Yarla, Devendra Kumar Pandey
pp. 158-164 · DOI: 10.5530/ijpi.2021.2.29Vol. 11, Issue 2 (2021)Objectives: The present work was aimed to determine the effect on the Phospholipase A2 (PLA2) enzyme and conduct its antioxidant nature, phytochemical analyses of the Triphala compound’s extract, an Ayurvedic Rasayana ma…
Original ArticlePublished: 1 Jul 2021
Nidhi Gupta, Rakesh Sagar, Mohan Lal Kori
pp. 165-169 · DOI: 10.5530/ijpi.2021.2.30Vol. 11, Issue 2 (2021)Background: Chenopodium botrys L. is local to Europe and Asia and established in North America. The plant commonly used for the treatment of disease. The medicinal use of Chenopodium botrys is mainly due to mythology rat…
Original ArticlePublished: 1 Jul 2021
Abdul Rouf Wani, Kanchan Yadav
pp. 170-175 · DOI: 10.5530/ijpi.2021.2.31Vol. 11, Issue 2 (2021)Objectives: The main aim of this research was to evaluate phytochemicals, antimicrobial, antiproliferative and antioxidant Activities of the essential Oil of Monarda citriodora growing in Kashmir (India). Materials and M…
Original ArticlePublished: 1 Jul 2021
Mallela Vijaya Jyothi, Nayakanti Devanna, Akkiraju Sudheer
pp. 176-183 · DOI: 10.5530/ijpi.2021.2.32Vol. 11, Issue 2 (2021)Objectives: Atherosclerosis is caused by vascular inflammation and oxidative stress. Pro-atherogenic effect of hypercholesterolemia caused by impairment of nitric oxide generation due to activated arginase. The current s…
Original ArticlePublished: 1 Jul 2021
Ravindran Sumitha, Narasiman Banu, Swaminathan Vijayalakshmi, Venkatesan Krithika
pp. 184-188 · DOI: 10.5530/ijpi.2021.2.33Vol. 11, Issue 2 (2021)Background: Ocean acts as a wealthy resource of biological diversity producing prospective novel metabolites from the organisms present in the environment. Novel bioactive compounds from Echinoderms mainly from sea stars…
Original ArticlePublished: 1 Jul 2021
Bhushan Dnyandeo Varpe, Shailaja Bhanudas Jadhav
pp. 189-194 · DOI: 10.5530/ijpi.2021.2.34Vol. 11, Issue 2 (2021)Objectives: To synthesize Schiff base conjugate of 5-Fluoroisatin with thiophene-2-ethylamine and its Mannich bases and screen for anti-inflammatory and anti-tubercular activity. Materials and Methods: The compounds were…
Original ArticlePublished: 1 Jul 2021
Mateti Ashok, Mohammed Habibuddin, Jukanti Raju
pp. 195-203 · DOI: 10.5530/ijpi.2021.2.35Vol. 11, Issue 2 (2021)Background: Acyclovir (ACV) a 21-deoxy guanosine analogue effective against Herpes Simplex Virus (both type 1 and 2) and other viral diseases, mainly acts by inhibiting the viral DNA polymerase. The limited oral bioavail…
Original ArticlePublished: 1 Jul 2021
Ekramul Haque, Mohd Aamir Bin Riyaz, Sriram Shankar, Saqib Hassan
pp. 204-207 · DOI: 10.5530/ijpi.2021.2.36Vol. 11, Issue 2 (2021)Objectives: This study aimed to compositionally characterize the biosurfactant and its application in crude oil bioremediation. Methods: Production of biosurfactant was carried out in Bushnell Hass Broth (BHB), supplemen…
Original ArticlePublished: 1 Jul 2021
Sumanta Mondal, Sabyasachi Biswal, Trayambica Acharya, Prasenjit Mondal, Kausik Bhar
pp. 208-213 · DOI: 10.5530/ijpi.2021.2.37Vol. 11, Issue 2 (2021)Objectives: The present article involved the development of sensitive and validated Ultraviolet (UV) Spectrophotometric and reverse phase liquid chromatographic and method for the determination of lapatinib in bulk and p…
Original ArticlePublished: 1 Jul 2021
Ashish Kandalkar, Nitu Singh
pp. 214-219 · DOI: 10.5530/ijpi.2021.2.38Vol. 11, Issue 2 (2021)Objectives: The objective of this study is to extract Phytochemical constituent from Cinnamon Bark and to design and develop the transdermal patch of the herbal drug along with modern medicine Glibenclamide using solvent…
Original ArticlePublished: 1 Jul 2021
Dilip Kumar Patel, Roohi Kesharwani, Vikas Kumar
pp. 220-224 · DOI: 10.5530/ijpi.2021.2.39Vol. 11, Issue 2 (2021)Objectives: The present work focus on to create Solid lipid nanoparticles (SLN) and nanostructured lipid Carrier (NLC) as transporters for effective delivery of Etodolac (ETD). Methods: Etodolac stacked SLN and NLC were …
Original ArticlePublished: 1 Jul 2021
Vishwajeet Swami, Amir A Shaikh, Pooja N Jadhav, Rahul S Buchade
pp. 225-229 · DOI: 10.5530/ijpi.2021.2.40Vol. 11, Issue 2 (2021)Background: Microsponge is a class of dosage form containing porous nature containing drug that is targeted to achieve sustained action for prolong period. Microsponge based delivery system results in drug localization o…
Original ArticlePublished: 1 Jul 2021
Sindhoor Shridharan Mulleria, Koland Marina, Sawan Mukund Ghetia
pp. 230-237 · DOI: 10.5530/ijpi.2021.2.41Vol. 11, Issue 2 (2021)Background: Psoriasis is an autoimmune-mediated disease characterized marked by thickened plaques and erythematous skin, which can be treated by topical delivery of apremilast. The objective of this study was to prepare …
Original ArticlePublished: 1 Jul 2021
Sanjay Nipanikar, Narendra Mundhe, Vaishali Deshpande, Nitin Shinde, Mangesh Wakchaoure, Pravin Ghadge
pp. 238-243 · DOI: 10.5530/ijpi.2021.2.42Vol. 11, Issue 2 (2021)Background: Aphthous stomatitis is a painful and often inflammatory condition. Objective of the study is to evaluate safety and efficacy of Arimu mouth ulcer gel (AHPL/ AYTOP/2014A) in subjects suffering from aphthous ul…
Original ArticlePublished: 1 Jul 2021
Ruhul Amin, Biplab Kumar Dey, Suhaj Abdulsalim, Mohan K. Manu
pp. 244-247 · DOI: 10.5530/ijpi.2021.2.43Vol. 11, Issue 2 (2021)Objectives: Extensive literature survey revealed that chronic obstructive pulmonary disease (COPD) is one of the primary burdens for low-income countries like India. Out of around 30 million COPD patients in India, a con…