
International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 24Review Article
Review ArticlePublished: 1 Apr 2021
Shriniwas Pramod Patil, Rajesh Yadav Chaudhari
pp. 1-4 · DOI: 10.5530/ijpi.2021.1.1Vol. 11, Issue 1 (2021)Many attempts have been made for green synthesis of metal oxide nanoparticles; revealing the importance of plant extracts in reducing metal/ metal oxide precursor to nanoparticles and their applications in various scient…
Review ArticlePublished: 1 Apr 2021
Pradeep Kumar Yadalam, Deepavalli Arumuganainar, Rajapandian Kasipandian, Kalaivani Varatharajan
pp. 5-9 · DOI: 10.5530/ijpi.2021.1.2Vol. 11, Issue 1 (2021)Nanotechnology is of intense interest to researchers due to the basic fact that the properties of the material can be effectively manipulated when the size is transformed to nanoscopic. New opportunities arise out of the…
Original Article
Original ArticlePublished: 1 Apr 2021
Vitthal Chopade, Diksha Kamble
pp. 10-13 · DOI: 10.5530/ijpi.2021.1.3Vol. 11, Issue 1 (2021)Objectives: To green synthesize silver nanoparticles by using weed plant Tridax procumbens also prepare and check antimicrobial activity of silver nanoparticles impregnated bandages against one gram positive bacteria and…
Original ArticlePublished: 1 Apr 2021
Qazi Yasar, Zahid Zaheer
pp. 14-22 · DOI: 10.5530/ijpi.2021.1.4Vol. 11, Issue 1 (2021)Objectives: A novel series of 4-aminoantipyrine derivatives were designed and efficiently synthesized from Gewald, triphosgene and various substituted aromatic/ aliphatic/heterocyclic amines. Methods: The synthesized der…
Original ArticlePublished: 1 Apr 2021
Hossein Moein, Davoud Balarak, Ali Meshkinain, Kethineni Chandrika, Nastaran Yazdani
pp. 23-26 · DOI: 10.5530/ijpi.2021.1.5Vol. 11, Issue 1 (2021)Objectives: In this research, the efficiency of the Electrocoagulation (EC) process with aluminum electrodes in the removal of Tetracycline (TC) from synthetic solutions was studied. Methods: This study experimentally wa…
Original ArticlePublished: 1 Apr 2021
Debleena Roy, Renia Mullick, Namrata Chakraborty, Jayeesha Ghosh, Debapriya Das, Bidisha Mallick, Dipu Samanta
pp. 27-31 · DOI: 10.5530/ijpi.2021.1.6Vol. 11, Issue 1 (2021)Background: Antioxidants are substances that delays or inhibits the oxidation of a substrate by countering highly unstable entities (ROS and free radicals) that can cause cellular damage. Some natural source of antioxida…
Original ArticlePublished: 1 Apr 2021
Brindangnanam Pownraj, Meenatchi Ramu, Ekramul Haque
pp. 32-40 · DOI: 10.5530/ijpi.2021.1.7Vol. 11, Issue 1 (2021)Background: Enterococcus faecium is an emerging multidrug resistant opportunistic pathogen responsible for causing most of the nosocomial infections. Adhesins are the cell wall anchoring proteins implicated in the pathog…
Original ArticlePublished: 1 Apr 2021
Fredos Kord Mostafapour, Shaziya Haseeb, Davoud Balarak, Hossein Moein, Ali Akbar Sajadi, Zeynab Jalalzaei
pp. 41-45 · DOI: 10.5530/ijpi.2021.1.8Vol. 11, Issue 1 (2021)Objectives: The pollution of aquatic bodies by Naphthalene and antibiotics effluent from activities of many industry is a significant environmental challenge affecting the ecosystem. Batch process was used to remove Naph…
Original ArticlePublished: 1 Apr 2021
Shaileyee Das, Subhash C Mandal
pp. 46-51 · DOI: 10.5530/ijpi.2021.1.9Vol. 11, Issue 1 (2021)Objectives: Zingiber officinale Linn. is a rhizome commonly consumed as a culinary purpose, medicine or spice in India. The aim of this study was to evaluate potent anticancer leads from ginger rhizome peel. Methods: Cyt…
Original ArticlePublished: 1 Apr 2021
Sharada L Deore, Hrutuja P Tidke, Somshekhar S Khadabadi, Bhushan A Baviskar, Anajli A Kide, Bhavna P Shende
pp. 52-55 · DOI: 10.5530/ijpi.2021.1.10Vol. 11, Issue 1 (2021)Objectives: The objective of present research work is to develop simple, rapid and accurate high performance thin layer chromatographic method for quantitative estimation of silymarin in marketed hepatoprotective formula…
Original ArticlePublished: 1 Apr 2021
Suvarnalata Suhas Mahajan, RY Chaudhari, VR Patil
pp. 56-62 · DOI: 10.5530/ijpi.2021.1.11Vol. 11, Issue 1 (2021)Objectives: The objective of existent effort was topical proniosomal gel formulation and evaluation from the proniosomes of Ciclopirox to improve poor skin penetration and residence of the topical antifungal drugs. Metho…
Original ArticlePublished: 1 Apr 2021
Harshal Dilip Mahajan, Rajendra Dayaram Wagh, Dheeraj Tukaram Baviskar
pp. 63-68 · DOI: 10.5530/ijpi.2021.1.12Vol. 11, Issue 1 (2021)Objectives: The objective of present study aim towards promising potential of acyclovir containing Poly Lactic-Co-Glycolic Acid based nanoparticles for delivering drug to ocular cavity and could be view as alternative to…
Original ArticlePublished: 1 Apr 2021
Pankaj Bhatt, Suruchi Singh, Satish Kumar Sharma, Sani Rabiu
pp. 69-75 · DOI: 10.5530/ijpi.2021.1.13Vol. 11, Issue 1 (2021)Objectives: Aim of the present research work is to prepared fast mouth dissolving film of frovatriptan succinate monoydrate. Methods: Fast dissolving buccal film is prepared by Solvent casting method, hydroxypropyl methy…
Original ArticlePublished: 1 Apr 2021
Ramila Prajapati, Jayvadan Patel, Anita Patel
pp. 76-81 · DOI: 10.5530/ijpi.2021.1.14Vol. 11, Issue 1 (2021)Background: Psoriasis is a widespread chronic disease affecting 1-3% of total population and in most cases, treated by topical application of corticosteroids. Though, the topical route is very demanding because of the ph…
Original ArticlePublished: 1 Apr 2021
Krishnat Dhekale, Sharvil Patil, Ravindra Kamble
pp. 82-87 · DOI: 10.5530/ijpi.2021.1.15Vol. 11, Issue 1 (2021)Background: Multiwall Carbon Nanotubes (MWCNTs) have innovative characteristic features strongly associated with nanotechnology and drug delivery applications. Objectives: The current work was performed with an objective…
Original ArticlePublished: 1 Apr 2021
Rambod Barzigar, Nanjundappa Haraprasad, Basaralu Yadurappa Sathish Kumar, Mohammad Javad Mehran
pp. 88-93 · DOI: 10.5530/ijpi.2021.1.16Vol. 11, Issue 1 (2021)Background: The applications of transgenic plants in the healthcare system are immense. They offer an alternative strategy for the fabrication of antigenic determinants of medically important pathogens. Objectives: Cloni…
Original ArticlePublished: 1 Apr 2021
Ashish Kumar Verma, Mamta Farswan Singh, Akanksha Awasthi
pp. 94-98 · DOI: 10.5530/ijpi.2021.1.17Vol. 11, Issue 1 (2021)Background: The objective of this work were to study the effect of p38 MAP Kinase inhibitor (SB239063) and Vitamin (Vit) B12 on activity of p38 MAP kinase implicated in neuroinflammation. “In the central nervous system (…
Original ArticlePublished: 1 Apr 2021
Ashish Kumar Verma, Mamta Farswan Singh, Akanksha Awasthi
pp. 99-103 · DOI: 10.5530/ijpi.2021.1.18Vol. 11, Issue 1 (2021)Objectives: To evaluate the effect of MAP kinase inhibitor (SB239063) on neuroinflammation along with Vitamin B12. Materials and Methods: Male wistar albino rats divided in to eight groups each group having six animals. …
Original ArticlePublished: 1 Apr 2021
Garima Jain, Umesh Kumar Patil
pp. 104-107 · DOI: 10.5530/ijpi.2021.1.19Vol. 11, Issue 1 (2021)Objectives: The objective of present study is to determine the efficacy of ethanolic extract of Evolvulus alsinoides Linn. for therapeutics at various doses. One more purpose is also to determine anti-inflammatory effect…
Original ArticlePublished: 1 Apr 2021
Amin Maghamifar, Hossein Najafzadehvarzi, Seyedmohammad Hossaini
pp. 108-112 · DOI: 10.5530/ijpi.2021.1.20Vol. 11, Issue 1 (2021)Background: Rotenone is one of the most widely used pesticides in agriculture and may affect public health through the food chain. A possible mechanism of rotenone toxicity is oxidative stress. This study, the supportive…
