International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Review ArticlePublished: 6 Feb 2013
Pranav Patel, Hitesh Patel, Shital Panchal, Tejal Mehta
pp. 169-175 · DOI: 10.4103/2230-973X.106981Vol. 2, Issue 4 (2013)Tacrolimus (FK 506) is a potent macrolide lactone immunosuppressive agent used for prophylaxis of organ rejection after transplantation and graft‑versus‑host disease after bone marrow transplantation in patients. Moreove…
Original Research Article
Original Research ArticlePublished: 6 Feb 2013
Shailesh T Prajapati, Anant P Mehta, Ishan P Modhia, Chhagan N Patel
pp. 176-182 · DOI: 10.4103/2230-973X.106988Vol. 2, Issue 4 (2013)Purpose: The purpose of this research work was to formulate raft‑forming chewable tablets of H2 antagonist (Famotidine) using a raft‑forming agent along with an antacid‑ and gas‑generating agent.Materials and Methods: Ta…
Original Research ArticlePublished: 6 Feb 2013
Amish Ashvinkumar Dangi, Prakash Bhikhabhai Zalodiya
pp. 183-188 · DOI: 10.4103/2230-973X.106989Vol. 2, Issue 4 (2013)Purpose: The demand for melt-in-mouth tablets (MMTs) has been rapidly growing during the last decade, especially for the elderly and children who have swallowing difficulties, to avoid first-pass metabolism and quick dru…
Original Research ArticlePublished: 6 Feb 2013
Kevin Garala, Jaydeep Patel, Anjali Patel, Mihir Raval, Abhay Dharamsi
pp. 189-200 · DOI: 10.4103/2230-973X.106996Vol. 2, Issue 4 (2013)Purpose: The purpose of the present investigation was to improve the flow and mechanical properties of racecadotril by a crystallo‑co‑agglomeration (CCA) technique. Direct tableting is a requirement of pharmaceutical ind…
Original Research ArticlePublished: 6 Feb 2013
SB Shirsand, MS Para, D Nagendrakumar, KM Kanani, D Keerthy
pp. 201-207 · DOI: 10.4103/2230-973X.107002Vol. 2, Issue 4 (2013)Purpose: Niosomes play an increasingly important role in drug delivery as they can reduce toxicity and modify pharmacokinetic and bio-availability. Topically applied niosomes can increase the residence time of drugs in t…
Original Research ArticlePublished: 6 Feb 2013
Mayur Desai, Rishad R Jivani, Laxman D Patel, Noordin P Jivani, Bhavin Sonagara
pp. 208-212 · DOI: 10.4103/2230-973X.107005Vol. 2, Issue 4 (2013)Introduction: A tablet system consisting of cores coated with two layers of swelling and rupturable coatings was prepared and evaluated as time controlled chronomodulated tablet. Materials and Methods: Cores containing M…
Original Research ArticlePublished: 6 Feb 2013
Thakur Prasad Chaturvedi, Ruchi Srivastava, Anand Kumar Srivastava, Varun Gupta, Pushpendra Kumar Verma
pp. 213-217 · DOI: 10.4103/2230-973X.107007Vol. 2, Issue 4 (2013)Aim: Prevention of periodontal disease progression is the primary goal of periodontal therapy. When conventional therapy is found to be inadequate in achieving periodontal health in chronic periodontitis, local antimicro…
Letter to the Editor
Letter to the EditorPublished: 6 Feb 2013
Viroj Wiwanitkit
pp. 218 · DOI: 10.4103/2230-973X.107008Vol. 2, Issue 4 (2013)The editorial on delivery of nutraceuticals using nanotechnology is very interesting.[1] As noted, successful formulation of new nanosubstance is the hope. However, the effectiveness and safety is still the consideration…