International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 33Review Article
Review ArticlePublished: 15 Dec 2023
Jayant Kumar, Ajmera Ramkishan, Madhugiri Prakash Venkatesh
pp. 1-9 · DOI: 10.5530/ijpi.14.1.1Vol. 14, Issue 1 (2023)Bringing a new healthcare product to market can be challenging, especially when navigating the complex regulatory requirements of different countries. The approval process can be a maze of differing regulations, but this…
Review ArticlePublished: 15 Dec 2023
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Jayasheela Hiremath, Abhishek BJ, Saurav Raj, Megha Hegde, Dhananjay Tikadar, Raviteja Somashekhar Kanavi, Rohith Javali Veeresh
pp. 10-15 · DOI: 10.5530/ijpi.14.1.2Vol. 14, Issue 1 (2023)Background: The drug Finerenone, a selective the drug mineralocorticoid receptor antagonist, indicated for Chronic Kidney Disease (CKD) and Type 2 Diabetes. Recent researchers also found add on role in the management of …
Review ArticlePublished: 15 Dec 2023
Himangshu Deka, Ananta Choudhury, Jahnabi Sarmah, Debgopal Ganguly, Rosamund Jyrwa, Dhiraj Baishya, Nurjamal Houque
pp. 16-22 · DOI: 10.5530/ijpi.14.1.3Vol. 14, Issue 1 (2023)Diabetes mellitus is a global health concern resulting in significant morbidity and mortality. Till today there is no known cure available for the condition. The extended treatment schedule, unfavorable side effects of c…
Review ArticlePublished: 15 Dec 2023
Sepideh Kianian, Rozhin Moloudpour Toulakani, Fatemeh Zisti, Davoud Balarak, Shaziya Haseeb Siddiqui, Morteza Khodadadi Saloot
pp. 23-29 · DOI: 10.5530/ijpi.14.1.4Vol. 14, Issue 1 (2023)Background: The presence of antibiotic residues in water is a matter of concern for both public health and the environment, owing to the phenomenon of antibiotic resistance. One of the Advanced Oxidation Processes (AOPs)…
Review ArticlePublished: 15 Dec 2023
Rajesh Hadia, Vishal Singh, Nidhi Solanki, Shiwanand Sharma, Varunsingh Saggu, Cyril Sajan, Rahul Trivedi, Sunil Kardani, Sunil Baile, Hemraj Singh Rajput, Rajesh Maheshwari
pp. 30-38 · DOI: 10.5530/ijpi.14.1.5Vol. 14, Issue 1 (2023)Aim/Background: The Cytochrome P450 (CYP) enzyme family, consisting of 57 distinct genes, plays a pivotal role in various biological processes. These genes encode enzymes with multifaceted functions, impacting vital proc…
Review ArticlePublished: 15 Dec 2023
Shriniwas Pramod Patil, KV Ramanath, Hemant Kumar Jain, Charu Pandya, Bhagyashree Pawar, Seema V Pattewar
pp. 39-47 · DOI: 10.5530/ijpi.14.1.6Vol. 14, Issue 1 (2023)Since long back, many Lycopodiaceae or Huperziaceae plants species like Lycopodium clavatum L. serratum, Huperzia serrata, H. carinata, Phlegmariurus squarrosus and P. henryi are being traditionally used in treatment of …
Review ArticlePublished: 15 Dec 2023
Praveen Halagali, Rohan Singadi, Hunsur Ranganath Arjun, Gundada Sivaraj Rakshanaa, Salini Parameswaran Nair, Prashant Halagali, Preethi Somanna
pp. 48-54 · DOI: 10.5530/ijpi.14.1.7Vol. 14, Issue 1 (2023)Natural elements from nature along with their bioactive components are being extensively studied in recent times for their therapeutic efficacy in treating a variety of degenerative disorders. These diseases are specific…
Original Article
Original ArticlePublished: 15 Dec 2023
Amira Nabila Mat Roof, Richard Johari James, Salfarina Ramli, Boonchoo Sritularak, Pornchai Rojsitthisak, Hasseri Halim
pp. 55-61 · DOI: 10.5530/ijpi.14.1.8Vol. 14, Issue 1 (2023)Background: The imbalance level of Reactive Oxygen Species (ROS) in the body can lead to oxidative stress in cells, resulting in the progression of chronic diseases. Fargesin, a bioactive lignan found in Flos magnoliae, …
Original ArticlePublished: 15 Dec 2023
Akshay Shankpal, V. P. Yogita, R. Chinmayee, Santhosh Reddy, P. K. Lakshmi
pp. 62-67 · DOI: 10.5530/ijpi.14.1.9Vol. 14, Issue 1 (2023)Background: This study aimed to establish and promote drug information services for healthcare professionals and patients in a tertiary care hospital, and to assess the level of awareness and utilization of the center. M…
Original ArticlePublished: 15 Dec 2023
Charan Sailaja, Pradeep Kumar Bhupalam
pp. 68-75 · DOI: 10.5530/ijpi.14.1.10Vol. 14, Issue 1 (2023)Background: The work aimed to fabricate Loratadine (LRD) niosomes by employing a Box Behnken Design (BBD) and they were subsequently applied to transdermal patches utilizing BBD's solvent casting process.Materials and Me…
Original ArticlePublished: 15 Dec 2023
Gaurav Singh Sikarwar, Mukesh Kumar Gupta
pp. 76-88 · DOI: 10.5530/ijpi.14.1.11Vol. 14, Issue 1 (2023)Aim: The study’s goal was to develop and characterize a new type of Fenoprofen tablet that can float. Materials and Methods: Research on the drug’s performulation was carried out to evaluate its organoleptic qualities, s…
Original ArticlePublished: 15 Dec 2023
Piyusha Kolhe, Rahul Godge, Hrishikesh Ghorpade, Gaurav Dhanvate, Anurag Nalawade
pp. 89-100 · DOI: 10.5530/ijpi.14.1.12Vol. 14, Issue 1 (2023)Background: Antibiotic resistance is a growing concern, and the development of new anti-bacterial agents is crucial. 2-aminophenyl-2-(2,4,5-triphenylimidazole) derivatives have shown potential as anti-bacterial agents in…
Original ArticlePublished: 15 Dec 2023
Nandini Rebbbaniboni, Seetha Mahithavani, Gayatri Somayala, Malladi Venkata Srihari Lakshman, Jahnavi Bandla
pp. 101-106 · DOI: 10.5530/ijpi.14.1.13Vol. 14, Issue 1 (2023)Background: The primary objective of this research was to establish a spectrophotometric technique to quantitatively analyze the concentration of favipiravir in both its pure form and pharmaceutical preparations using br…
Original ArticlePublished: 15 Dec 2023
Thriveni Raunak Salian, Nadira Noushida, Benachakal Honnegowda Jaswanth Gowda, Manodeep Chakraborty, Sindhu Priya Enumadisetty Srinivasulu, Mohammed Gulzar Ahmed
pp. 107-116 · DOI: 10.5530/ijpi.14.1.14Vol. 14, Issue 1 (2023)Background: Resveratrol (3,4,5-trihydroxystilbene), a polyphenol derived from plant sources, despite its cardioprotective properties, has limited therapeutic impact due to its low in vivo bioavailability and rapid metabo…
Original ArticlePublished: 15 Dec 2023
Himanshu Sharma, Phool Chandra
pp. 117-126 · DOI: 10.5530/ijpi.14.1.15Vol. 14, Issue 1 (2023)Background: Many parts of the brain experience excruciating pain as a result of Alzheimer's disease, a form of dementia. Cognitive processes and neuropsychiatric regulation are disrupted by the numerous neuropathologies …
Original ArticlePublished: 15 Dec 2023
Anjana Chandran, Marina Koland, Sindhoor Shridharan Mulleria
pp. 127-134 · DOI: 10.5530/ijpi.14.1.16Vol. 14, Issue 1 (2023)Background: Acyclovir is a widely used anti-viral drug that has low bioavailability when administered orally and is also difficult to administer parenterally due to its inherent solubility limitations. Buccal administrat…
Original ArticlePublished: 15 Dec 2023
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Akash Chathamvelli, Kadambari Patil, Anirudh Pai, Aditi Baadkar
pp. 135-140 · DOI: 10.5530/ijpi.14.1.17Vol. 14, Issue 1 (2023)Background: Tuberculosis (TB), a highly contagious and dangerous disease, impacts millions globally, with India topping the list of affected countries. The study aimed to evaluate the knowledge, attitude, practice, and m…
Original ArticlePublished: 15 Dec 2023
Santosh B Patil, Pramod C Gadad
pp. 141-150 · DOI: 10.5530/ijpi.14.1.18Vol. 14, Issue 1 (2023)Background: Genetic metabolic illnesses called Glycogen Storage Disease type I (GSD I) are caused due to abnormalities in the glucose-6-phosphatase enzyme complex involved in the metabolism of glycogen. Objectives: The c…
Original ArticlePublished: 15 Dec 2023
Neha Gaikwad, Charushila Bhangale, Sangita Bhandare
pp. 151-159 · DOI: 10.5530/ijpi.14.1.19Vol. 14, Issue 1 (2023)Objectives: The key objective of this work is to establish a stability-indicating UHPLC technique for measuring amlodipine and enalapril maleate in bulk and pharmaceutical formulations Materials and Methods: The mobile p…
Original ArticlePublished: 15 Dec 2023
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Abhishek B J, Amisha Netalakar, Bhoomika S K, Namratha D, Tahameen K Kurabanavar
pp. 160-164 · DOI: 10.5530/ijpi.14.1.20Vol. 14, Issue 1 (2023)Background: Cardiovascular Disease (CVD) is commonly known as disease of heart of blood vessels and is typically composed of fatty deposits. Heart attack and Heart failure are caused by the high levels of fatty tissues b…