International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
EditorialPublished: 18 Feb 2012
Javed Ali
pp. 199 · DOI: 10.4103/2230-973X.93002Vol. 1, Issue 4 (2012)Topical eye drops are the most common dosage form for treating disorder related to the anterior segment of the eye. However, a large amount of drug delivered through the eye drops is lost through tear drainage and associ…
Review Article
Review ArticlePublished: 18 Feb 2012
Sagar Makwana, Biswajit Basu, Yogita Makasana, Abhay Dharamsi
pp. 200-206 · DOI: 10.4103/2230-973X.93004Vol. 1, Issue 4 (2012)Parenteral administration of pharmaceutical products is one of the most popular methods used to produce quick onset of action and also 100% bioavailability. Main problem occurs with the parenteral drug delivery is lack o…
Original Research Article
Original Research ArticlePublished: 18 Feb 2012
Sanjay J Kshirsagar, Shrikant V Patil, Mangesh R Bhalekar
pp. 207-213 · DOI: 10.4103/2230-973X.93005Vol. 1, Issue 4 (2012)Introduction: A pulsatile drug delivery system is characterized by a lag time that is an interval of no drug release followed by rapid drug release. The purpose of this work was to develop hollow calcium alginate beads f…
Original Research ArticlePublished: 18 Feb 2012
Shantanu V Lale, Monu Goyal, Arvind K Bansal
pp. 214-221 · DOI: 10.4103/2230-973X.93007Vol. 1, Issue 4 (2012)Introduction: The purpose of the present study was to screen excipients such as amino acids and non-aqueous solvents for their stabilizing effect on catalase, a model protein, for lyophilization. The present study also i…
Original Research ArticlePublished: 18 Feb 2012
Santosh S Bhujbal, Sunita S Hadawale, Parag A Kulkarni, Jayant S Bidkar, Vidya A Thatte, Clarine A Providencia, Rupesh R Yeola
pp. 222-226 · DOI: 10.4103/2230-973X.93009Vol. 1, Issue 4 (2012)Background and Aim: Momordica charantia Linn. is traditionally used as a medicine for diabetes. The present investigation was aimed to formulate and evaluate transdermal patchesof Momordica charantia Linn. Materials and …
Original Research ArticlePublished: 18 Feb 2012
Archana S Patil, Panchaxari M Dandagi, Vinayak S Masthiholimath, Anand P Gadad, Basavaraj K Najwade
pp. 227-223 · DOI: 10.4103/2230-973X.93010Vol. 1, Issue 4 (2012)Background: Hypertension shows circadian rhythm that there is a rise in pressure from the time of waking or before (about 4 to 8 a.m.), in most people. Conventional drug delivery system of captopril is inappropriate for …
Original Research ArticlePublished: 18 Feb 2012
Rachna Prasad, Sneh Anand, Veena Koul
pp. 234-239 · DOI: 10.4103/2230-973X.93011Vol. 1, Issue 4 (2012)Introduction: The effect of DC iontophoresis using low (0.2 mA/cm2) and high current density (0.5 mA/cm2) on transdermal permeation of methotrexate loaded into polyacrylamide hydrogel patch was investigated. Results: Flu…
Original Research ArticlePublished: 18 Feb 2012
Prabhakar Prabhu, Samip Shah, Shankar Gundad
pp. 240-246 · DOI: 10.4103/2230-973X.93008Vol. 1, Issue 4 (2012)Aim and Background: Domperidone is a dopamine antagonist with antiemetic properties having a plasma half life of 7-9 h with 15% oral bioavailability. In the present work transdermal patches of domperidone were prepared w…
Original Research ArticlePublished: 18 Feb 2012
Dasharath M Patel, Mehul J Patel, Ankit N Patel, Chhagan N Patel
pp. 247-254 · DOI: 10.4103/2230-973X.93006Vol. 1, Issue 4 (2012)Introduction: Present investigation describes an influence of ratio of Gelucire 43/01(hydrophobic) to hydroxypropyl methylcellulose K4M (HPMC K4M) (hydrophilic) and different fillers on release of famotidine from gastro-…
Letter to the Editor
Letter to the EditorPublished: 18 Feb 2012
Barkat Ali Khan
pp. 255 · DOI: 10.4103/2230-973X.93003Vol. 1, Issue 4 (2012)I have read the editorial note titled 'Plagiarism: an editor's concern' by Dr Javed Ali and found it a bold and great decision by IJPI. Plagiarism is a serious contravention in modern age academic writing and research an…