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International Journal of Pharmaceutical Investigation

Volume 1, Issue 4

2012 · pp. 199–255 · 10 articles

Volume
1
Issue
4
Year
2012
Published
18 Feb 2012
Pages
199–255
Articles
10
Sections
4
ISSN
2230-9713
Journal
IJPI

In this issue

Editorial

  1. EditorialPublished: 18 Feb 2012

    Javed Ali

    pp. 199 · DOI: 10.4103/2230-973X.93002Vol. 1, Issue 4 (2012)

    Topical eye drops are the most common dosage form for treating disorder related to the anterior segment of the eye. However, a large amount of drug delivered through the eye drops is lost through tear drainage and associ…

Review Article

  1. Review ArticlePublished: 18 Feb 2012

    Sagar Makwana, Biswajit Basu, Yogita Makasana, Abhay Dharamsi

    pp. 200-206 · DOI: 10.4103/2230-973X.93004Vol. 1, Issue 4 (2012)

    Parenteral administration of pharmaceutical products is one of the most popular methods used to produce quick onset of action and also 100% bioavailability. Main problem occurs with the parenteral drug delivery is lack o…

Original Research Article

  1. Original Research ArticlePublished: 18 Feb 2012

    Sanjay J Kshirsagar, Shrikant V Patil, Mangesh R Bhalekar

    pp. 207-213 · DOI: 10.4103/2230-973X.93005Vol. 1, Issue 4 (2012)

    Introduction: A pulsatile drug delivery system is characterized by a lag time that is an interval of no drug release followed by rapid drug release. The purpose of this work was to develop hollow calcium alginate beads f…

  2. Original Research ArticlePublished: 18 Feb 2012

    Shantanu V Lale, Monu Goyal, Arvind K Bansal

    pp. 214-221 · DOI: 10.4103/2230-973X.93007Vol. 1, Issue 4 (2012)

    Introduction: The purpose of the present study was to screen excipients such as amino acids and non-aqueous solvents for their stabilizing effect on catalase, a model protein, for lyophilization. The present study also i…

  3. Original Research ArticlePublished: 18 Feb 2012

    Santosh S Bhujbal, Sunita S Hadawale, Parag A Kulkarni, Jayant S Bidkar, Vidya A Thatte, Clarine A Providencia, Rupesh R Yeola

    pp. 222-226 · DOI: 10.4103/2230-973X.93009Vol. 1, Issue 4 (2012)

    Background and Aim: Momordica charantia Linn. is traditionally used as a medicine for diabetes. The present investigation was aimed to formulate and evaluate transdermal patchesof Momordica charantia Linn. Materials and …

  4. Original Research ArticlePublished: 18 Feb 2012

    Archana S Patil, Panchaxari M Dandagi, Vinayak S Masthiholimath, Anand P Gadad, Basavaraj K Najwade

    pp. 227-223 · DOI: 10.4103/2230-973X.93010Vol. 1, Issue 4 (2012)

    Background: Hypertension shows circadian rhythm that there is a rise in pressure from the time of waking or before (about 4 to 8 a.m.), in most people. Conventional drug delivery system of captopril is inappropriate for …

  5. Original Research ArticlePublished: 18 Feb 2012

    Rachna Prasad, Sneh Anand, Veena Koul

    pp. 234-239 · DOI: 10.4103/2230-973X.93011Vol. 1, Issue 4 (2012)

    Introduction: The effect of DC iontophoresis using low (0.2 mA/cm2) and high current density (0.5 mA/cm2) on transdermal permeation of methotrexate loaded into polyacrylamide hydrogel patch was investigated. Results: Flu…

  6. Original Research ArticlePublished: 18 Feb 2012

    Prabhakar Prabhu, Samip Shah, Shankar Gundad

    pp. 240-246 · DOI: 10.4103/2230-973X.93008Vol. 1, Issue 4 (2012)

    Aim and Background: Domperidone is a dopamine antagonist with antiemetic properties having a plasma half life of 7-9 h with 15% oral bioavailability. In the present work transdermal patches of domperidone were prepared w…

  7. Original Research ArticlePublished: 18 Feb 2012

    Dasharath M Patel, Mehul J Patel, Ankit N Patel, Chhagan N Patel

    pp. 247-254 · DOI: 10.4103/2230-973X.93006Vol. 1, Issue 4 (2012)

    Introduction: Present investigation describes an influence of ratio of Gelucire 43/01(hydrophobic) to hydroxypropyl methylcellulose K4M (HPMC K4M) (hydrophilic) and different fillers on release of famotidine from gastro-…

Letter to the Editor

  1. Letter to the EditorPublished: 18 Feb 2012

    Barkat Ali Khan

    pp. 255 · DOI: 10.4103/2230-973X.93003Vol. 1, Issue 4 (2012)

    I have read the editorial note titled 'Plagiarism: an editor's concern' by Dr Javed Ali and found it a bold and great decision by IJPI. Plagiarism is a serious contravention in modern age academic writing and research an…