International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Review ArticlePublished: 21 Feb 2014
Aditya Ganeshpurkar, Ankit Ganeshpurkar, Vikas Pandey, Abhishek Agnihotri, Divya Bansal, Nazneen Dubey
pp. 1-4 · DOI: 10.4103/2230-973X.127733Vol. 4, Issue 1 (2014)It seems to be a necessary need to develop an effective drug carrier system for targeted delivery of pharmaceuticals. Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigen…
Original Research Article
Original Research ArticlePublished: 21 Feb 2014
Kushal Pal Singh, Gulshan Chhabra, Vijay Sharma, Kamla Pathak
pp. 5-14 · DOI: 10.4103/2230-973X.127734Vol. 4, Issue 1 (2014)Aim: The aim of the present work was to explore the development of a dual-controlled release periodontal system of a potent broad spectrum fi rst-generation fl uoroquinolone, ciprofl oxacin, and the anti-infl ammatory en…
Original Research ArticlePublished: 21 Feb 2014
Suneela Pyreddy, Pandurangan Dinesh Kumar, Palanirajan Vijayaraj Kumar
pp. 15-18 · DOI: 10.4103/2230-973X.127735Vol. 4, Issue 1 (2014)Aim: The preparation of novel PEGylated PAMAM (poly-amidoamine) dendrimers for delivery of anti-HIV drug Efavirenz is reported. Method and Materials: About 5.0 G PAMAM dendrimers are prepared by ethylene diamine core via…
Original Research ArticlePublished: 21 Feb 2014
K Rama Koteswara Rao, K Rajya Lakshmi
pp. 19-26 · DOI: 10.4103/2230-973X.127736Vol. 4, Issue 1 (2014)Objective: The objective of the present work was to formulate and to characterize a fl oating drug delivery system for clopidogrel bisulphate to improve bioavailability and to minimize the side effects of the drug such a…
Original Research ArticlePublished: 21 Feb 2014
Shailesh T Prajapati, Manoj V Patel, Chhaganbhai N Patel
pp. 27-31 · DOI: 10.4103/2230-973X.127737Vol. 4, Issue 1 (2014)Aim: Zolmitriptan is a 5-HT receptor agonist (1B/1D). It is used in the acute treatment of migraine having low bioavailability about 40% orally due to hepatic first pass metabolism. The purpose of the present research wa…
Original Research ArticlePublished: 21 Feb 2014
Keyur S Patel, Mandev B Patel
pp. 32-37 · DOI: 10.4103/2230-973X.127738Vol. 4, Issue 1 (2014)Objectives: The objective of present study was to develop chitosan-based sustained release nicorandil microspheres to reduce the dosing frequency. Materials and Methods: The nicorandil-loaded chitosan microspheres were f…
Original Research ArticlePublished: 21 Feb 2014
Iizhar Ahmed Syed, P Niveditha, Ismail Ahmad
pp. 38-45 · DOI: 10.4103/2230-973X.127739Vol. 4, Issue 1 (2014)Introduction: The polyelectrolyte Complexes (PECs) are based on ionic cross-linking. They have been employed to prepare a sustained release matrix tablets. These systems are based upon the fact that their structure can e…