International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Review ArticlePublished: 15 Feb 2016
Rima B. Shah, Manhar Patel, David M. Maahs, Viral N. Shah
pp. 1-9 · DOI: 10.4103/2230-973X.176456Vol. 6, Issue 1 (2016)Many patients with advanced type 2 diabetes mellitus (T2DM) and all patients with T1DM require insulin to keep blood glucose levels in the target range. The most common route of insulin administration is subcutaneous ins…
Original Research Article
Original Research ArticlePublished: 15 Feb 2016
Ebere I Okoye, Anthony O Onyekweli
pp. 10-22 · DOI: 10.4103/2230-973X.176461Vol. 6, Issue 1 (2016)Aim: The aim was to develop a novel excipient from Pleurotus tuber-regium (PT)-cornstarch (CS) mixture and evaluate its multifunctional characteristics in tablet formulation. Materials and Methods: Composites were genera…
Original Research ArticlePublished: 15 Feb 2016
Garima Thakur, Amrinder Singh, Inderbir Singh
pp. 23-31 · DOI: 10.4103/2230-973X.176468Vol. 6, Issue 1 (2016)Composite transdermal films of chitosan (CS)/montmorillonite K 10 (MMT) clay were prepared for the delivery of curcumin. CS/MMT films were evaluated for various physicochemical parameters. The films were characterized by…
Original Research ArticlePublished: 15 Feb 2016
Franklin C. Kenechukwu, Mumuni A. Momoh, Emmanuel C. Umeyor, Emmanuel M. Uronnachi, Anthony A. Attama
pp. 32-38 · DOI: 10.4103/2230-973X.176473Vol. 6, Issue 1 (2016)Background: The aim of this study was to formulate solidified reverse micellar solution (SRMS)-based solid lipid microparticles (SLMs) using homolipids from tallow fat (Bos indicus) and evaluate its potential for enhance…
Original Research ArticlePublished: 15 Feb 2016
Neha Sureshrao Raut, Swapnil Jamaiwar, Milind Janrao Umekar, Nandkishor Ramdas Kotagale
pp. 39-46 · DOI: 10.4103/2230-973X.176474Vol. 6, Issue 1 (2016)Introduction: This study focused on the potential effects of compression forces experienced during lactose (InhaLac 70, 120, and 230) storage and transport on the flowability and aerosol performance in dry powder inhaler…
Original Research ArticlePublished: 15 Feb 2016
Renuka Mishra, Priyanka Joshi, Tejal Mehta
pp. 47-55 · DOI: 10.4103/2230-973X.176487Vol. 6, Issue 1 (2016)Objective: The objective of the present investigation was formulation, optimization and characterization of mucoadhesive film of clotrimazole (CT) which is patient-convenient and provides an effective alternative for the…
Original Research ArticlePublished: 15 Feb 2016
Dinesh Kumar Pandurangan, Prathima Bodagala, Vijayaraj Kumar Palanirajan, Saravanan Govindaraj
pp. 56-62 · DOI: 10.4103/2230-973X.176488Vol. 6, Issue 1 (2016)In the present investigation, solid lipid nanoparticles (SLNs)-loaded in situ gel with voriconazole drug was formulated. Further, the formulation was characterized for pH, gelling capacity, entrapment efficiency, in vitr…
Original Research ArticlePublished: 15 Feb 2016
Shamsuddin s, Mohammad Fazil, Shahid Husain Ansari, Javed Ali
pp. 63-68 · DOI: 10.4103/2230-973X.176490Vol. 6, Issue 1 (2016)Introduction: Solubility and dissolution of a poor water-soluble drug are the two major barriers for formulation scientists in development of drug delivery. Many of the potent drugs do not show the therapeutic effects du…