International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
EditorialPublished: 15 Jul 2015
Ramandeep Singh Narang, Jasjeet Kaur Narang
pp. 121-123 · DOI: 10.4103/2230-973X.160843Vol. 5, Issue 3 (2015)Nanotechnology is directed at manipulating matter at the nanometer level and the application of the same to medicine is called nanomedicine. Over the past few years researchers have developed various nanomedicines for di…
Review Article
Review ArticlePublished: 15 Jul 2015
Charu Bharti, Upendra Nagaich, Ashok Kumar Pal, Neha Gulati
pp. 124-133 · DOI: 10.4103/2230-973X.160844Vol. 5, Issue 3 (2015)Due to lack of specifi cation and solubility of drug molecules, patients have to take high doses of the drug to achieve the desired therapeutic effects for the treatment of diseases. To solve these problems, there are va…
Original Research Article
Original Research ArticlePublished: 15 Jul 2015
Mona Alibolandi, Fatemeh Sadeghi, Seyed Hossein Sazmand, Seyed Mohammad Shahrokhi, Mahmoud Seifi, Farzin Hadizadeh
pp. 134-141 · DOI: 10.4103/2230-973X.160846Vol. 5, Issue 3 (2015)Introduction: The copolymer of polyethylene glycol (PEG) and polyesters has many interesting properties, such as amphiphilicity, biocompatibility, biodegradability, and self-assembly in an aqueous environment. Diblock co…
Original Research ArticlePublished: 15 Jul 2015
Pawan Kumar, Shailendra Kumar Singh, Dina Nath Mishra, Priti Girotra
pp. 142-146 · DOI: 10.4103/2230-973X.160850Vol. 5, Issue 3 (2015)Introduction: Ketorolac tromethamine (KT), a nonsteroidal anti-infl ammatory drug, when given orally causes gastrointestinal disturbances. Its transdermal drug delivery may reduce such side effects associated with them. …
Original Research ArticlePublished: 15 Jul 2015
Manikandan Mahalingam, Kannan Krishnamoorthy
pp. 147-154 · DOI: 10.4103/2230-973X.160852Vol. 5, Issue 3 (2015)Introduction: The objective of this investigation was to design and optimize the experimental conditions for the fabrication of camptothecin (CPT) loaded Eudragit S 100. Nanoparticles, and to understand the effect of var…
Original Research ArticlePublished: 15 Jul 2015
Deepak Sharma, Gilphy Philip, Reema Gabrani, Javed Ali, Shweta Dang
pp. 155-160 · DOI: 10.4103/2230-973X.160853Vol. 5, Issue 3 (2015)Aim and Objectives: In the present investigation dual agents i.e., hesperidin and diazepam loaded polymeric nanoparticles (NPs) were formulated by nanoprecipitation method and optimized using three-level factorial design…
Original Research ArticlePublished: 15 Jul 2015
Priya Shahi, Neeraj Kumari, Kamla Pathak
pp. 161-170 · DOI: 10.4103/2230-973X.160854Vol. 5, Issue 3 (2015)The objective of the present work was to develop a novel delivery system of ketorolac tromethamine (KT) for dual pulse release based on microspheres and tablet in capsule system (MATICS) as a treatment modality for rheum…
Original Research ArticlePublished: 15 Jul 2015
Adinarayana Gorajana, Adhiyaman Rajendran, Lee Mun Yew, Kamal Dua
pp. 171-178 · DOI: 10.4103/2230-973X.160857Vol. 5, Issue 3 (2015)Aim: The objective of the current study is to increase the dissolution rate of cefuroxime axetil (CA) by formation of binary CA solid dispersion using water soluble carriers such as polyvinylpyrrolidone (PVP K30) and pol…