International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 36Review Article
Review ArticlePublished: 30 Jun 2024
Akram Ahmed Aloqbi
pp. 595-606 · DOI: 10.5530/ijpi.14.3.72Vol. 14, Issue 3 (2024)This review provides an extensive summary of the most current expansions on the therapeutic potential of ginger bioactive compounds in the context of cancer management. We delve into the individual components of ginger a…
Review ArticlePublished: 30 Jun 2024
Pratheksha Suresh, Vivek Reddy Murthannagari, Ganesh Gonna Nandhi Krishnan, Neerej Shivashankar, Tholkapiyan Mullaiventhan
pp. 607-615 · DOI: 10.5530/ijpi.14.3.73Vol. 14, Issue 3 (2024)Historically, there have been constraints on pediatric drug trials, resulting in an absence of authorized medicines for children and a significant reliance on off-label use. Pediatric drug development is critical to addr…
Review ArticlePublished: 30 Jun 2024
Prachi Pandey, Rahul Pal, Vinay Kumar Rao Khadam, Himmat Singh Chawra, Ravindra Pal Singh
pp. 616-632 · DOI: 10.5530/ijpi.14.3.74Vol. 14, Issue 3 (2024)Targeted drug delivery systems are employed to administer pharmaceutical medication, facilitating the precise delivery of drugs to specific diseased areas. Several drug delivery systems utilise carriers such as antibodie…
Review ArticlePublished: 30 Jun 2024
Koushik Narayan Sarma, Chandrashekar Thalluri, Jithendar Reddy Mandhadi
pp. 633-646 · DOI: 10.5530/ijpi.14.3.75Vol. 14, Issue 3 (2024)Pharmaceutical formulations, polymer-based nanofibers, which have higher surface area per unit mass of solid, enable and contribute to functions linked to surface shape. Nanofibers can be made using a number of different…
Review ArticlePublished: 30 Jun 2024
Fatmah Alsharif
pp. 647-656 · DOI: 10.5530/ijpi.14.3.76Vol. 14, Issue 3 (2024)This review article explores the transformative impact of Artificial Intelligence (AI) and Machine Learning (ML) in cancer research. It focuses on the critical role of AI in medical imaging for cancer detection, explorin…
Review ArticlePublished: 30 Jun 2024
Gaurav Tiwari, Sagar Narendra Ande, Varsha Deva, Nayyar Parvez, Mahesh Kumar Posa, Saumya Singh, Ruchi Tiwari
pp. 657-669 · DOI: 10.5530/ijpi.14.3.77Vol. 14, Issue 3 (2024)All patients with Chronic Obstructive Pulmonary Disease (COPD), a multifactorial illness, have decreased post-bronchodilator lung function. While it was once believed that hyperresponsiveness and acute bronchodilator rev…
Review ArticlePublished: 30 Jun 2024
K H Harish, Agadi Hiremath Viswanatha Swamy
pp. 670-680 · DOI: 10.5530/ijpi.14.3.78Vol. 14, Issue 3 (2024)Agmatine, an endogenous amine with cationic properties, serves as a precursor for polyamine synthesis and has diverse pharmacological effects on the central nervous system. Its neuroprotective mechanisms include preventi…
Review ArticlePublished: 30 Jun 2024
Umashankar Chikkanna, M Balakeshawa Ramaiah, Shanmuganathan Seetharaman, Vijayan Venugopal, Anandakirouchenane Elumalai, Chandrakala Venkatesh, Gururaj Giligarr
pp. 681-695 · DOI: 10.5530/ijpi.14.3.79Vol. 14, Issue 3 (2024)This thorough analysis of the article describes the therapeutic potential of herbal treatments, such as ginger, papaya, bamboo shoots, and Plectranthus species, in addressing the complex issues of oxidative stress, micro…
Review ArticlePublished: 30 Jun 2024
Manish Kumar Gautam, Pritish Kumar Panda, Anubhav Dubey, Mamta Kumari, Niladry Sekhar Ghosh
pp. 696-701 · DOI: 10.5530/ijpi.14.3.80Vol. 14, Issue 3 (2024)Background: Zebrafish have emerged as an invaluable asset in biomedical research, particularly in comparison to other vertebrate models employed for studying human ailments. Their efficacy in large-scale studies of genet…
Original Article
Original ArticlePublished: 30 Jun 2024
K Swathi Priya, Veda Priya Gummadi, Gana Manjusha Kondepudi
pp. 702-711 · DOI: 10.5530/ijpi.14.3.81Vol. 14, Issue 3 (2024)Objectives: This study aims to assess the potential antidiabetic properties of aqueous extracts derived from the peels of specific fruits, including A.squamosa, C. melo, A. deliciosa and M. pumila. Materials and Methods:…
Original ArticlePublished: 30 Jun 2024
Basavaraj Dinnimath, Mahesh Palled, Shradha Sutar, Shradha Tashildar, Utkarsh Chavan, Sampada Ganpule
pp. 712-737 · DOI: 10.5530/ijpi.14.3.82Vol. 14, Issue 3 (2024)Organometallic compounds are gaining prominence today as they are found to be potent anticancer agents due to their diverse chemical nature along with the metal with which they are chelated. In these organometallic compo…
Original ArticlePublished: 30 Jun 2024
Lakshmi Usha Ayalasomayajula, Chandra Sekhar Patro, Saroj Kumar Raul
pp. 738-748 · DOI: 10.5530/ijpi.14.3.83Vol. 14, Issue 3 (2024)Background: The present work covers the preparation and investigation of Nanoemulsion (NE) based hydrogel i.e., Nanoemulgel (NEG) of an Antifungal drug Oxiconazole delivered topically. Materials and Methods: High-speed h…
Original ArticlePublished: 30 Jun 2024
Prashant Halagali, Vishal I Wannur, Abishek Kumar A Patil, Vaibhavi D. Torgal, Shrikrishna M Naik, Santosh A Marennavar, Sakshi Shahapurmath, Pankaj Patil
pp. 749-758 · DOI: 10.5530/ijpi.14.3.84Vol. 14, Issue 3 (2024)Introduction: Ethosomes are non-invasive drug delivery systems that enable drugs to enter the bloodstream or deep layers of the skin and these are phospholipid-based elastic Nano vesicles with a high ethanol concentratio…
Original ArticlePublished: 30 Jun 2024
Suvarna Sanjay Khairnar, Mohammed Saad, Jubershaha Salimshaha Fakir, Yogesh Suresh Ahire, Ziyaurrahman Ataurrahman, Nayana Kailas Patil
pp. 759-767 · DOI: 10.5530/ijpi.14.3.85Vol. 14, Issue 3 (2024)Aim/Background: Alcohol-induced liver necrosis requires effective treatment. This study tests Polyherbal Extract’s hepatoprotective effects on alcohol-induced liver necrosis in rats. The extract’s impact on inflammatory …
Original ArticlePublished: 30 Jun 2024
Parag Patgiri, Biru Goyary, Mritunjoy Kumar Roy, Ananta Swargiary, Nisha Rani Brahma, Bihung Brahma
pp. 768-774 · DOI: 10.5530/ijpi.14.3.86Vol. 14, Issue 3 (2024)Background: Resistance to insecticides is one of the major problems in successfully controlling of mosquito-borne diseases. The present study explores the role of Voltage-Gated Sodium Channel (VGSC) and their mutation in…
Original ArticlePublished: 30 Jun 2024
Sandeep S Sagare, Ashok Patil, B S Prasad, S Kadambari
pp. 775-785 · DOI: 10.5530/ijpi.14.3.87Vol. 14, Issue 3 (2024)Background: Ayurveda, an ancient holistic health system, underscores personalized well-being through tailored approaches to health and disease. The post Vamana-Virechana procedures are vital in Ayurvedic detox, promoting…
Original ArticlePublished: 30 Jun 2024
Naveena Katta, Ashwini Madhava, Preethi Sudheer
pp. 786-793 · DOI: 10.5530/ijpi.14.3.88Vol. 14, Issue 3 (2024)Background: This study aimed to develop an efficient drug delivery system targeting the colon to treat inflammatory conditions using mesalamine. The approach involved formulating microsponges with Eudragit polymers, focu…
Original ArticlePublished: 30 Jun 2024
Shaffi Khurana Tangri, G gnanarajan, Vaibhav Sisodiya, Himanshu Rana, Mehak Garg, Pranshu Tangri, Vaishali Pathania
pp. 794-805 · DOI: 10.5530/ijpi.14.3.89Vol. 14, Issue 3 (2024)Background: This study’s objective was to create and assess diacerein-loaded microsponges incorporated into a topical gel formulation for enhanced skin delivery. Diacerein is a potent anti-inflammatory agent used in the …
Original ArticlePublished: 30 Jun 2024
Dipti Gohil, Dixit Patel, Nirmal Shah, Chintan Aundhia, Sunil Kardani, Rahul Trivedi
pp. 806-813 · DOI: 10.5530/ijpi.14.3.90Vol. 14, Issue 3 (2024)Background: Topical alpha agonists approved by the FDA are used to treat rosacea. Because of its potent vasoconstrictor properties, brimonidine tartrate topical gel (0.33%) efficiently reduces erythema. The aim of this i…
Original ArticlePublished: 30 Jun 2024
Sunanda Thakur, Putta Venkata Nagendra Kumar, Kamal Shah, Medari Ravinder, Subhash Bhima Pawar, Byalla Sadasivaiah, P Shivakumar Singh, Nagendra Singh Chauhan
pp. 814-821 · DOI: 10.5530/ijpi.14.3.91Vol. 14, Issue 3 (2024)Background: Bio formation of the silver nanoparticles are eco-friendly, low cost, within short period could synthesised and widespread significances also performances. Objectives: Seldom, the creation of extra-cellular s…