International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
EditorialPublished: 7 Dec 2012
Ningning Yang
pp. 97-98 · DOI: 10.4103/2230-973X.104388Vol. 2, Issue 3 (2012)Gene therapy has been investigated a lot in both basic research and clinical trials.[1] The first antisense oligodeoxyribonucleotide (ODN) drug, Vitravene (Fomivirsen), was approved by the United States Food and Drug Adm…
Review Article
Review ArticlePublished: 7 Dec 2012
Shweta Handoo, Vandana Arora, Deepak Khera, Prafulla Kumar Nandi, Susanta Kumar Sahu
pp. 99-105 · DOI: 10.4103/2230-973X.104392Vol. 2, Issue 3 (2012)The regulatory requirements of various countries of the world vary from each other. Therefore, it is challenging for the companies to develop a single drug which can be simultaneously submitted in all the countries for a…
Review ArticlePublished: 7 Dec 2012
Mohammad Tariq, Zeenat Iqbal, Javed Ali, Sanjula Baboota, Sushama Talegaonkar, Zulfiqar Ahmad, Jasjeet K Sahni
pp. 106-122 · DOI: 10.4103/2230-973X.104394Vol. 2, Issue 3 (2012)Periodontitis is the most common localized dental inflammatory disease related with several pathological conditions like inflammation of gums (gingivitis), degeneration of periodontal ligament, dental cementum and alveol…
Original Research Article
Original Research ArticlePublished: 7 Dec 2012
Shivang A Chaudhary, Aliasgar F Shahiwala
pp. 123-133 · DOI: 10.4103/2230-973X.104395Vol. 2, Issue 3 (2012)Introduction: Common cold is the most frequently recurring disease in the world and is a leading cause of doctor visits and missed days from school and work. Cold reliever medicated chewing gum (MCG) will be a definitive…
Original Research ArticlePublished: 7 Dec 2012
Hitesh V Chavda, Rupal D Patel, Ishan P Modhia, Chhagan N Patel
pp. 134-139 · DOI: 10.4103/2230-973X.104396Vol. 2, Issue 3 (2012)Introduction: Superporous hydrogel (SPH) swells very rapidly in a shorter period of time to an equilibrium size and contains highly porous structure.Aim: The synthesis of SPH of poly (acrylamide-co-acrylic acid) and its …
Original Research ArticlePublished: 7 Dec 2012
Vidya Sabale, Sejal Vora
pp. 140-149 · DOI: 10.4103/2230-973X.104397Vol. 2, Issue 3 (2012)Background: The purpose of this study was to develop microemulsion-based hydrogel formulation for topical delivery of bifonazole with an objective to increase the solubility and skin permeability of the drug. Materials a…
Original Research ArticlePublished: 7 Dec 2012
G Vijayaranga Vittal, R Deveswaran, S Bharath, BV Basavaraj, V Madhavan
pp. 150-156 · DOI: 10.4103/2230-973X.104398Vol. 2, Issue 3 (2012)Introduction: Liquisolid technique is used in delivery of lipophilic and poorly water soluble drugs through oral route. It involves dissolving water insoluble drugs in nonvolatile solvents and converting into acceptably …
Original Research ArticlePublished: 7 Dec 2012
Tallapaneni Vishnuvardhan Rao, GB Kiran Kumar, Mohammed Gulzar Ahmed, Vedamurthy Joshi
pp. 157-161 · DOI: 10.4103/2230-973X.104399Vol. 2, Issue 3 (2012)Aim and Background: The novelty of the present study was to control the release profile of matrix tablets of losartan potassium prepared by using different concentrations of chitosan and trisodium citrate as cross-linkin…
Original Research ArticlePublished: 7 Dec 2012
Shailesh T Prajapati, Parth B Patel, Chhagan N Patel
pp. 162-168 · DOI: 10.4103/2230-973X.104400Vol. 2, Issue 3 (2012)Objective: Sumatriptan succinate is a selective 5-hydroxytryptamine-1 receptor agonist effective in the acute treatment of migraine headaches, having low bioavailability of about 15% orally due to first-pass metabolism. …