International Journal of Pharmaceutical Investigation · Archive
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In this issue
Editorial
EditorialPublished: 4 Jun 2012
Javed Ali
pp. 1 · DOI: 10.4103/2230-973X.96919Vol. 2, Issue 1 (2012)First and foremost I express heartfelt appreciation to all authors and reviewers of the first year ofInternational Journal of Pharmaceutical Investigation (IJPI) on behalf of the entire editorial board and the publisher.…
Review Article
Review ArticlePublished: 4 Jun 2012
Gaurav Tiwari, Ruchi Tiwari, Birendra Sriwastawa, L Bhati, S Pandey, P Pandey, Saurabh K Bannerjee
pp. 2-11 · DOI: 10.4103/2230-973X.96920Vol. 2, Issue 1 (2012)Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are…
Review ArticlePublished: 4 Jun 2012
Swati Sareen, George Mathew, Lincy Joseph
pp. 12-17 · DOI: 10.4103/2230-973X.96921Vol. 2, Issue 1 (2012)This article is intended to combine recent literature on solid dispersion technology for solubility enhancement with special emphasis on mechanism responsible for the same by solid dispersion, various preparation methods…
Invited Article
Invited ArticlePublished: 4 Jun 2012
Gergely Szakonyi, Romána Zelkó
pp. 18-25 · DOI: 10.4103/2230-973X.96922Vol. 2, Issue 1 (2012)In this paper we give an overview about the interaction of water molecules with pharmaceutical excipients. Most of these excipients are amorphous or partially amorphous polymers and their characteristics are very sensiti…
Original Research Article
Original Research ArticlePublished: 4 Jun 2012
R Indira Prasanna, K Uma Sankari
pp. 26-33 · DOI: 10.4103/2230-973X.96923Vol. 2, Issue 1 (2012)Background: Glibenclamide (G) is a popular anti-diabetic drug, belonging to the class of sulfonylurea. The drug is widely used for treating type II diabetes but it undergoes first-pass effect. A novel aspiration in treat…
Original Research ArticlePublished: 4 Jun 2012
SB Shirsand, Sarasija Suresh, GG Keshavshetti, PV Swamy, P Vijay Prakash Reddy
pp. 34-41 · DOI: 10.4103/2230-973X.96924Vol. 2, Issue 1 (2012)Introduction: In the present study, mucoadhesive buccal bilayer tablets of atenolol were fabricated with the objective of avoiding first pass metabolism and to improve its bioavailability with reduction in dosing frequen…
Original Research ArticlePublished: 4 Jun 2012
Manju Nagpal, Rampal Rajera, Kalpana Nagpal, Pankaj Rakha, SK Singh, DN Mishra
pp. 42-47 · DOI: 10.4103/2230-973X.96925Vol. 2, Issue 1 (2012)Objective: The aim of present investigation is to enhancein vitro dissolution of poorly soluble drug glimepiride by preparing solid dispersions using modified gum karaya. Materials and Methods: Solid dispersions of drug …
Original Research ArticlePublished: 4 Jun 2012
Anil Kumar Singhal, Edwin E Jarald, Ahmad Showkat, Anwar Daud
pp. 48-51 · DOI: 10.4103/2230-973X.96926Vol. 2, Issue 1 (2012)Background: Moringa gum obtained from stem of the plant Moringa oleifera Lam. belonging to family Moringaceae. Number of naturally occurring polysaccharides obtained from plant (guar gum, inulin), animal (chitosan, chond…