International Journal of Pharmaceutical Investigation · Archive
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In this issue
1–20 of 24Review Article
Review ArticlePublished: 27 Jul 2022
Utkarsh Ghate, Hema Kulkarni, Manasi Deshpande, Mandar Akkalkotkar
pp. 250-254 · DOI: 10.5530/ijpi.2022.3.45Vol. 12, Issue 3 (2022)Molecular docking studies are used to identify cultivated/ abundant herbs such as Coriander, Burmuda grass or Asparagus as potential replacement for Seeta Ashoka- Saraca asoca (Roxb.) De Wilde, syn. S. indica Linn. a rar…
Original Article
Original ArticlePublished: 27 Jul 2022
Raseema Raheema Sharafudeen, Annie Abraham, Reshma Usha Soman
pp. 255-259 · DOI: 10.5530/ijpi.2022.3.46Vol. 12, Issue 3 (2022)Background: The coconut palm is so much more than just a tree; because all of this is essential with medicinal benefits. Coconut inflorescence sap (CIS) is the sweet, oyster-white colored, non-fermented juice tapped from…
Original ArticlePublished: 27 Jul 2022
Snigdha Bhardwaj, Pushpraj S Gupta
pp. 260-271 · DOI: 10.5530/ijpi.2022.3.47Vol. 12, Issue 3 (2022)Background: Pseudomonas aeruginosa (P. aeruginosa) is considered as one of the most opportunistic pathogens that may infect humans and led to increase in bacterial virulence or pathogenicity. P. aeruginosa exhibits varie…
Original ArticlePublished: 27 Jul 2022
Anoop Kumar, Ashutosh Mishra
pp. 272-279 · DOI: 10.5530/ijpi.2022.3.48Vol. 12, Issue 3 (2022)Background: The colon targeted drug delivery system is mainly useful for the topical treatment of colon diseases such as ulcerative colitis, Crohn’s disease OR colorectal cancers where we attain high local concentration …
Original ArticlePublished: 27 Jul 2022
Rajasekhar Pinnamaneni, Udaya Sri Puttagunta
pp. 280-287 · DOI: 10.5530/ijpi.2022.3.49Vol. 12, Issue 3 (2022)Background: Herbicides are classified either by toxicity or by mechanism of action, based on the chemical nature of the compound. Herbicides fall into two categories. Contact the herbicide and the transferred herbicide. …
Original ArticlePublished: 27 Jul 2022
Hina Bagada, Vishva Bhut, Himaxi Parmar
pp. 288-292 · DOI: 10.5530/ijpi.2022.3.50Vol. 12, Issue 3 (2022)Background: Prochlorperazine maleate is an antipsychotic and antiemetic drug that is available as tablets on the market for oral administration. The main object of this research work is to develop and validate the easies…
Original ArticlePublished: 27 Jul 2022
Ravisinh Vikramsinh Solanki, Ravi Bharatkumar Patel, Rajeshkumar Kanubhai Patel, Binal Manojkumar Patel
pp. 293-298 · DOI: 10.5530/ijpi.2022.3.51Vol. 12, Issue 3 (2022)Objectives: A selective, precise and accurate RP-HPLC stability indicating assay method has been developed for the simultaneous estimation of Azilsartan medoxomil and Cilnidipine in tablet dosage form. Materials and Meth…
Original ArticlePublished: 27 Jul 2022
Mandeep Kumar Singh, Umesh Kumar Patil
pp. 299-316 · DOI: 10.5530/ijpi.2022.3.52Vol. 12, Issue 3 (2022)Objectives: The silymarin phytosome (SPY) was developed to improve the solubility and dissolution. The prepared phytosome was evaluated for hemolytic, membrane stabilization activity, and in vivo acute and subchronic tox…
Original ArticlePublished: 27 Jul 2022
Ashish Yashwantrao Pawar, Ashvini Dhanraj Tapkir, Jyoti Bramhesh Rao, Rushikesh Pramod Dayama
pp. 317-322 · DOI: 10.5530/ijpi.2022.3.53Vol. 12, Issue 3 (2022)Background: The pharmaceutical industries are keen in development of new herbal bioactive molecules with an improved effect and less toxicity in order to replace synthetic drugs. Constipation is the most prevalent medica…
Original ArticlePublished: 27 Jul 2022
Manjunath Pobbathi Nagaraj, Avinash Kumar Seth, Anand Kandkere Ravindra Kumar, Vivekanandan Sundaramurthy
pp. 323-327 · DOI: 10.5530/ijpi.2022.3.54Vol. 12, Issue 3 (2022)Background: Circadian rhythms is a natural process that regulates the sleep wake cycle which is associated with several physiological, biochemical, endocrine, behavioural processes in humans and entrainment to light-dark…
Original ArticlePublished: 27 Jul 2022
Anita Ricablanca, Ami Abbott, Fatimata Sonago, Montserrat Garcia, Rachel Primacio, Eric Patten, Mudassar Iqbal Arain, Eduardo Fricovsky
pp. 328-333 · DOI: 10.5530/ijpi.2022.3.55Vol. 12, Issue 3 (2022)Background: These studies examined mutual protective relationships among rabbit muscle aldolase, enolase, phosphofructokinase-1 (PFK-1) and LDH from inhibitions by ascorbate (AA). It was proposed earlier that specific in…
Original ArticlePublished: 27 Jul 2022
Patricia Gaitan-Hahn, Anita Ricablanca, Ami Abbott, Jessica Chadwick, Alicia Thomas, Nathalia Cruz, Alice Deng, Leah Ordinanza, Mudassar Iqbal Arain, Eduardo Fricovsky
pp. 334-339 · DOI: 10.5530/ijpi.2022.3.56Vol. 12, Issue 3 (2022)Background: Previous studies suggested that glycogen storage was facilitated by ascorbate inhibition of phosphofructokinase-1 (PFK-1) in resting mammalian muscle; these studies showed that purified PFK-1 from fish or chi…
Original ArticlePublished: 27 Jul 2022
Shamli S Gupte, Arti Rathour, Divya Gupta, Richa Soni, Sadhana Shrivastava, Monika Bhaduria, Satendra Kumar Nirala, Shubham Singh, Anjali Sharma, Deepa Yadav, Samrat Rakshit, Sangeeta Shukla
pp. 340-345 · DOI: 10.5530/ijpi.2022.3.57Vol. 12, Issue 3 (2022)Background: Tephrosia purpurea (TP), commonly known as wild indigo, is traditionally used in treatment of splenomegaly. It is an important ingredient of various Ayurvedic medicines used in treatment of liver diseases. Ob…
Original ArticlePublished: 27 Jul 2022
V. V. Rajesham, Ruqaiya Jabeen, Mitta Raghavendra, P. Roshan Ali, T. Rama Rao
pp. 346-350 · DOI: 10.5530/ijpi.2022.3.58Vol. 12, Issue 3 (2022)Background: Renal disease is a significant issue of global proportions and renal damage is very prevalent as the kidney has the ability to excrete toxic substances to assess the protective impact of the Ethanolic extract…
Original ArticlePublished: 27 Jul 2022
Ranjana R, Deepak Kumar Singh, Bhaskar Laxman Jadhav
pp. 351-357 · DOI: 10.5530/ijpi.2022.3.59Vol. 12, Issue 3 (2022)Background: Diabetes mellitus is a metabolic disorder that causes millions of deaths throughout the world every year, and today also its incidence is on the increase. Many antidiabetic drugs are available in the pharmace…
Original ArticlePublished: 27 Jul 2022
Udaykumar Girdharlal Vegad, Devang Jagdishbhai Pandya
pp. 358-362 · DOI: 10.5530/ijpi.2022.3.60Vol. 12, Issue 3 (2022)Background: Gojihva or Gaozaban, an Ayurvedic cum Unani Medicinal plant described with various properties, including diuretic activity. Onosma bracteata Wall. is considered the official species of Gojihva in Ayurveda and…
Original ArticlePublished: 27 Jul 2022
Arti Akash Bhimanwar, M M Ghaisas, R V Shete
pp. 363-369 · DOI: 10.5530/ijpi.2022.3.61Vol. 12, Issue 3 (2022)Introduction: Huntington’s disease is considered as the autosomal dominating with progression of neuro-degeneration with decreased cognitive function and behaviour changes. Bioflavonoids promote memory, learning, and cog…
Original ArticlePublished: 27 Jul 2022
Vikram Nimbalkar, Niraj Vyawahare
pp. 370-374 · DOI: 10.5530/ijpi.2022.3.62Vol. 12, Issue 3 (2022)Background: The aim of the present study was to examine the protective potential of L-carnitine against Cisplatin-induced liver fibrosis in experimental models. Materials and Methods: The rats were randomly divided into …
Original ArticlePublished: 27 Jul 2022
Muhammad Irfan Bashir, Nur Hidayah Kaz Abdul Aziz, Dzul Azri Mohamed Noor
pp. 375-379 · DOI: 10.5530/ijpi.2022.3.63Vol. 12, Issue 3 (2022)Background: Monoamine oxidase-A (MAO-A) enzyme is responsible for the breakdown of monoamines (serotonin and norepinephrine). MAO-A is also a target to treat the depressive disorders. Kruppel-likefactor11(KLF11) and Sirt…
Original ArticlePublished: 27 Jul 2022
Sara Shahid, Fahad Ahmed, Amna Bajwa, Muhammad Ans, Anosh Sana, Sameen Abbas, Asma Fareed Khan, Aiman Mahmood, Qandeel Rafi, Shakeel Ahmad, Asifa Anwar, Rabeel Khan, Gul Shahnaz, Asad Majeed Khan
pp. 380-385 · DOI: 10.5530/ijpi.2022.3.64Vol. 12, Issue 3 (2022)Introduction: Metered-dose inhalers are the most widely prescribed and dispensed inhaler devices worldwide for the management of asthma. The present study aimed to access the impact of educational intervention on the com…