International Journal of Pharmaceutical Investigation · Archive
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In this issue
Review Article
Review ArticlePublished: 28 Dec 2021
Kakuli Chakraborty, Pratiti Ghosh
pp. 345-348 · DOI: 10.5530/ijpi.2021.4.61Vol. 11, Issue 4 (2021)P-glycoprotein is an efflux transporter belonging to the ATP Binding Cassette (ABC) family of transporters and is encoded by Multidrug resistance (MDR1) gene. It is primarily involved in efflux of xenobiotics that permea…
Review ArticlePublished: 28 Dec 2021
Mausami Vaghela, Pankaj Kapupara
pp. 349-353 · DOI: 10.5530/ijpi.2021.4.62Vol. 11, Issue 4 (2021)Regardless of a product’s country of registration, a current and updated pharmaceutical product dossier is mandatory. But any kind of post-approval change to pharmaceutical products requires prior permission or at least …
Original Article
Original ArticlePublished: 28 Dec 2021
Suresh Babu Bastipati, Chepuri Kalyani, Chidepudi Devi Sri Lalitha Naga Tulasi, Lavudi Saida
pp. 354-357 · DOI: 10.5530/ijpi.2021.4.63Vol. 11, Issue 4 (2021)Objectives: In the present study, the anticancer potential of the plant extracts of Elytraria acaulis L. (E. acaulis L.) were investigated on human breast cancer cells (MDAMB-231). Methods: Different organic solvent extr…
Original ArticlePublished: 28 Dec 2021
Swapnil Prakash Chaudhari, Dheeraj Tukaram Baviskar
pp. 358-361 · DOI: 10.5530/ijpi.2021.4.64Vol. 11, Issue 4 (2021)Background: The aim of present study is to evaluate the anti-inflmmatory activity of Chlorella vulgaris in acute and chronic experimental inflammatory model. Plant extract was analyzed for photochemical screening of diff…
Original ArticlePublished: 28 Dec 2021
Brindha Sundaramoorthy, Achintya Kumar Mandal, Vinayak Soman, Shree Devi Munusamy Sampangiramulu, Sunil Kumar Koppala Narayana, Shakila Ramachandran, Sathiyarajeswaran Parameswaran, Kiruthiga Ganesan
pp. 362-367 · DOI: 10.5530/ijpi.2021.4.65Vol. 11, Issue 4 (2021)Introduction: Siddha being one of the ancient systems of medicine, has been counted on by most of the population during the outbreak of pandemics in recent times. The decoctions like nilavempu kutinir and kapacura kutini…
Original ArticlePublished: 28 Dec 2021
Sumera Mehfooz, Abdul Wadud, Hamiduddin H, Rajeev Ranjan
pp. 368-373 · DOI: 10.5530/ijpi.2021.4.66Vol. 11, Issue 4 (2021)Background: Kushta, a dosage form of Unani medicine is prepared by employing well-designed procedures. The correct procedure ensures the production of Kamil (perfect) Kushta considered as safe, while a deviation from the…
Original ArticlePublished: 28 Dec 2021
Megha Tukaram Salve, Shailaja Bhanudas Jadhav
pp. 374-378 · DOI: 10.5530/ijpi.2021.4.67Vol. 11, Issue 4 (2021)Background: Diabetes is a long-term illness characterized by high blood sugar levels. It is estimated that by 2045, there will be nearly 693 million diabetic patients worldwide, with half of the population remaining undi…
Original ArticlePublished: 28 Dec 2021
Puteri Heryani Supriatna, Harmita Harmita, Yahdiana Harahap
pp. 379-383 · DOI: 10.5530/ijpi.2021.4.68Vol. 11, Issue 4 (2021)Objectives: The δ15N, δ13C, and δ2 H profile of the ephedrine as a methamphetamine precursor is a fingerprint to describing its origin. The origin of the precursor is one of the supporting data in methamphetamine profili…
Original ArticlePublished: 28 Dec 2021
Ferdos Kord Mostafapour, Maryam Bazi, Shaziya Haseeb Siddiqui, Hossein Bagheri, Davoud Balarak
pp. 384-388 · DOI: 10.5530/ijpi.2021.4.69Vol. 11, Issue 4 (2021)Background: Antibiotics have lasting effects on the environment. Among the properties of these substances are non-biodegradable, carcinogenic, high toxicity, and an increase in antibiotic-resistant bacteria. Therefore, t…
Original ArticlePublished: 28 Dec 2021
B Sreenatha Gupta, Madhusudhan Rao Vallabhaneni
pp. 389-394 · DOI: 10.5530/ijpi.2021.4.70Vol. 11, Issue 4 (2021)Background: Electrochemistry was the foremost subdivision of the chemistry its interred correlated to the entire other chemistries. Primarily it can settle on the nature of compound reactions by physically depends on the…
Original ArticlePublished: 28 Dec 2021
Shaik Reehana, Kamepalli Sujana
pp. 395-402 · DOI: 10.5530/ijpi.2021.4.71Vol. 11, Issue 4 (2021)Background: Palbociclib is anti-cancer drug which interacts with cyclindependent kinase. There are no methods repoRTed for the characterization of palbociclib together with degradation products (DPs). The main aim of the…
Original ArticlePublished: 28 Dec 2021
Hyma Ponnaganti, Ramesh Alluri, Jyothi Vemuri
pp. 403-407 · DOI: 10.5530/ijpi.2021.4.72Vol. 11, Issue 4 (2021)Background: Systems of floating drug delivery have a bulk density less than gastric fluids and thus it remains buoyant in the stomach without having any effect on gastric emptying rate for prolonged period of time. Rilpi…
Original ArticlePublished: 28 Dec 2021
Ankita Tiwari, Sanjay K Jain
pp. 408-413 · DOI: 10.5530/ijpi.2021.4.73Vol. 11, Issue 4 (2021)Background: Curcumin has been extensively employed in the treatment of several diseases in traditional medicine, including cancer.The main obstacles that avert its approval as a therapeutic moiety are its low aqueous sol…
Original ArticlePublished: 28 Dec 2021
Neelam Pawar, Anoop Parmar, Kavita Bahmani, DN Mishra, Renu Malik, Neha Minocha, Pawan Jalwal, Rahul Pawar
pp. 414-419 · DOI: 10.5530/ijpi.2021.4.74Vol. 11, Issue 4 (2021)Background: The optimization study was conducted in an attempt to develop a non-pressurized topical spray of Lidocaine without propellant. Methods: Central composite design was selected to determine the best conditions f…
Original ArticlePublished: 28 Dec 2021
Archana Nerella, MV Nagabhushanam
pp. 420-425 · DOI: 10.5530/ijpi.2021.4.75Vol. 11, Issue 4 (2021)Background: Owing to overcome the dissolution limited bioavailability of Meloxicam, the current research involves the development of Orodispersible films using Meloxicam by employing Quality by Design. Methods: In this w…
Original ArticlePublished: 28 Dec 2021
Amar Prashad Chaudhary, Jeswin George, Kaveri Kadowade, Lubna Faiyza, Rabiya Anjum, Uma V M, Sharath K N
pp. 426-431 · DOI: 10.5530/ijpi.2021.4.76Vol. 11, Issue 4 (2021)Background: This survey aims to determine medication compliance among hypertension patients and discover factors influencing medication compliance. Methods: This study incorporated a cross-sectional study design. The Hil…
Original ArticlePublished: 28 Dec 2021
Jisha Annie, RC Doijad, Emmanuel James
pp. 432-436 · DOI: 10.5530/ijpi.2021.4.77Vol. 11, Issue 4 (2021)Background: To analyze the drug prescription pattern for secondary prevention of stroke, medication adherence, knowledge and awareness about the disease, direct medical cost involved in the treatment of stroke. Methods: …
Original ArticlePublished: 28 Dec 2021
Swati Siddheshwar Londhe, Amol Arun Joshi, Geeta Narsingrao Sapkale, Mangesh Gautam Bhosale
pp. 437-440 · DOI: 10.5530/ijpi.2021.4.78Vol. 11, Issue 4 (2021)Background: The skin is a very sensitive protective layer for the human body and is exposed to environmental pollution, so it is very important to protect the skin. Facial skin can be protected by using various cosmetics…
Short Communication
Short CommunicationPublished: 28 Dec 2021
Rashmi Wadhwa, Pankaj Gupta
pp. 441-443 · DOI: 10.5530/ijpi.2021.4.79Vol. 11, Issue 4 (2021)Background: The current study focuses in vitro anti-inflammatory and anti-proliferative evaluation of the alcoholic extract of euphorbia hirta roots. Anti-inflammatory potential was screened by incorporating inhibition o…