International Journal of Pharmaceutical Investigation · Archive
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In this issue
21–34 of 34Original Article(continued)
Original ArticlePublished: 12 Feb 2025
Diptimayee Jena, Asra Jabeen, Akash Deep Mahato, Khush Choudhary, Roshan Mahato, Pakhi Chakraborty, Kirtimaya Mishra
pp. 524-530 · DOI: 10.5530/ijpi.20250120Vol. 15, Issue 2 (2025)Background: Green chemistry, also known as environmentally sustainable chemistry, is an area of study within a field of chemistry with the main goal of reducing the negative effects associated with chemical reactions and…
Original ArticlePublished: 12 Feb 2025
Ali Mahzari, Eman H. Khalifa, Ali A Zaeri, Hanan E Alyahyawi, Wanian M Alwanian, Saad M. Wali, Ohood Almuzaini, Yazeed Alshuweishi
pp. 531-542 · DOI: 10.5530/ijpi.20250138Vol. 15, Issue 2 (2025)Background: Cardiovascular diseases comprehend a array of situations that disturb the heart and blood vessels, making them a principal cause of morbidity and mortality worldwide. Dyslipidemia, an imbalance in lipids, suc…
Original ArticlePublished: 12 Feb 2025
S Mrudhulla, R.T Narendhirakannan
pp. 543-561 · DOI: 10.5530/ijpi.20250143Vol. 15, Issue 2 (2025)Background: Aegle marmelos, commonly known as bael, is a medicinal plant native to India with well-established use in traditional medicine systems. Materials and Methods: This study aims to evaluate the antioxidant, anti…
Original ArticlePublished: 12 Feb 2025
Nirali Doshi, Bijal Prajapati, Lavanya Selvaraj
pp. 562-572 · DOI: 10.5530/ijpi.20250144Vol. 15, Issue 2 (2025)Background: Pharmacovigilance studies analyzing Adverse Drug Reactions (ADRs) play a crucial role in understanding the ADR profile at tertiary care centers. The objective of this study is to identify, analyze and underst…
Original ArticlePublished: 12 Feb 2025
Sara Shahid, Maryam Ayesha, Muhammad Fahad, Maryam Mughal, Areej Kainat, Hamda Shakir, Muhammad Ali Tahir, Ansa Ijaz, Qurat-ul-Ain, Saad Saeed Alqahtani, Muhammad Zahid Iqbal
pp. 573-582 · DOI: 10.5530/ijpi.20250152Vol. 15, Issue 2 (2025)Background: A significant number of parents lack knowledge about vaccine-preventable diseases and hold misconceptions regarding the components, side effects and effectiveness of vaccines. A lack of understanding regardin…
Original ArticlePublished: 12 Feb 2025
Shweta Sulakude, Nisha Shirkoli
pp. 583-591 · DOI: 10.5530/ijpi.20250153Vol. 15, Issue 2 (2025)Background: Almotriptan Malate is a selective serotonin receptor agonist developed for migraine management in adults. Its bioavailability is 69.1%, with an elimination half-life of 3 hours and has low aqueous solubility.…
Original ArticlePublished: 12 Feb 2025
Heena Mittal, Sudhakar Kaushik, Bhawana Bhatt, Assem Babbar
pp. 592-603 · DOI: 10.5530/ijpi.20250154Vol. 15, Issue 2 (2025)Background: Solubility is the most vital parameter in the formulation of different drug delivery systems and one of the core concepts of the formulations. More than 50% of the new drug molecules are facing poor solubilit…
Original ArticlePublished: 12 Feb 2025
Monish Mukul Das, Sayan Chakraborty
pp. 604-613 · DOI: 10.5530/ijpi.20250155Vol. 15, Issue 2 (2025)Background: Uninterrupted spread of drug-resistant tuberculosis has necessitated prioritization of new and effective antitubercular compound. This investigation aimed to apply in silico methods to find out potential inhi…
Original ArticlePublished: 12 Feb 2025
Adarsh Arun Patil, Shailendra Sanjay Suryawanshi
pp. 614-630 · DOI: 10.5530/ijpi.20250067Vol. 15, Issue 2 (2025)Introduction: The growing focus on natural products in drug discovery has led to a deeper investigation of phytochemicals from traditional medicinal plants. Terminalia chebula, known for its broad range of therapeutic us…
Original ArticlePublished: 12 Feb 2025
K. Lalitha, M.P. Kusuma
pp. 631-641 · DOI: 10.5530/ijpi.20250116Vol. 15, Issue 2 (2025)Background: Tofacitinib Citrate (TCB) is a selective Janus kinase inhibitor approved by the USFDA for the treatment of Rheumatoid arthritis. However, TCB faces extensive first pass metabolism and causes GI trouble on ora…
Original ArticlePublished: 12 Feb 2025
Satish Kumar Dewangan, Shrikant R Inchulkar, Sangeeta Bhagat, Trilochan Satapathy, Nagendra Singh Chauhan
pp. 642-649 · DOI: 10.5530/ijpi.20250151Vol. 15, Issue 2 (2025)Background: Agad Tantra deals with poison and its manifestation, investigation, and treatment. It also deals with medicine having poisonous ingredients which always needs to be evaluated for its toxicity. In India the dr…
Original ArticlePublished: 12 Feb 2025
Synergistic Antidepressant Effect of Ginkgo biloba and Withania somnifera Using Experimental Animals
Vinod Ashokdas Bairagi, Rutika Mahendra Kharnare, Kajal Satish Nikam, Yogesh Suresh Ahire
pp. 650-656 · DOI: 10.5530/ijpi.20250013Vol. 15, Issue 2 (2025)Aim: This study involved the antidepressant activity of Ginkgo biloba and Withania somnifera in mice. Depressive disorder is a prevalent psychiatric Condition, affecting 21% of the global population. The currently used d…
Original ArticlePublished: 12 Feb 2025
Rakshita Paladi, Srajana Shetty, Sachin Basavaraj, Pratik Naveenkumar Magadum, Shashidhar Mallikarjun Javali, Shivmantesh Ashok Kittur, Veeresh Hubballi, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Vishwanath Swamy
pp. 657-663 · DOI: 10.5530/ijpi.20251868Vol. 15, Issue 2 (2025)Background: Cardiovascular diseases damage the heart and blood arteries. Cardiovascular disorders account for 31% of all fatalities worldwide, ultimately resulting in death, according to the WHO. A blood clot (thrombosis…
Original ArticlePublished: 12 Feb 2025
Ibrahim Baje Syed, Madhavi Nannapaneni
pp. 664-674 · DOI: 10.5530/ijpi.20251515Vol. 15, Issue 2 (2025)Aim/Background: To develop and validate a sensitive, accurate, simple, precise and cost-effective receptive and understandable method for concurrent evaluation of Gramicidin, Neomycin and Triamcinolone acetonide and thei…