
International Journal of Pharmaceutical Investigation · Archive
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In this issue
21–36 of 36Original Article(continued)
Original ArticlePublished: 27 Sep 2024
Gopi Chand Raguri, Koushik Yetukuri, Rama Rao Nadendla
pp. 1174-1180 · DOI: 10.5530/ijpi.14.4.128Vol. 14, Issue 4 (2024)Introduction: The discovery of new drugs is crucial for pharmaceutical research, development and patient care. One way to achieve this goal is by repurposing existing pharmaceuticals, which can provide valuable insights …
Original ArticlePublished: 27 Sep 2024
Tripti Pendharkar, Abhijeet Soni, Jagdeep Singh Dua, Utpal Jana
pp. 1181-1191 · DOI: 10.5530/ijpi.14.4.129Vol. 14, Issue 4 (2024)Background: Rhinitis is a prevalent condition affecting individuals of all age groups, resulting from factors such as cold, nasal infections, allergies, inflammation, and sinusitis. The diverse compositions of bioactive …
Original ArticlePublished: 27 Sep 2024
Muhammad Abid Mustafa, Hamza Farooq, Emaan Asif, Aqsa Saleem, Muqadas Amin, Hamna Shafiq, Alvina Shabbir, Haseeb Anwar, Mahgull Mahmood, Muhammad Shahmir Ahsan, Akifa Bashir
pp. 1192-1200 · DOI: 10.5530/ijpi.14.4.130Vol. 14, Issue 4 (2024)Background: The study explores transdermal drug delivery as a solution to traditional oral and parenteral administration challenges, highlighting improvements in efficiency and scope with micro needle technology. Objecti…
Original ArticlePublished: 27 Sep 2024
Naseera Kannanthodi Pariyapurath, Selvaraj Jagannathan, Maghimaa Mathanmohun, Sarika Baburajan Pillai, Kavitha Dhandapani, Rahul Gandhi Pachamuthu, Shivanandappa Kukkaler Channappa, Sivakumar Sakthivel, Hemapriya Namassivayam
pp. 1201-1207 · DOI: 10.5530/ijpi.14.4.131Vol. 14, Issue 4 (2024)Background: Nipah virus is a deadly infectious virus that was first isolated and identified from Malaysia. Since then, a number of Nipah virus outbreaks have been reported from Bangladesh and India. Transmission of the d…
Original ArticlePublished: 27 Sep 2024
Faruk Alam, Josef Yakin, Subham Ghosh, Surabhi Mandal, Moidul Islam Judder, Pynshailang Dkhar, Pratyushpal Kashyap
pp. 1208-1215 · DOI: 10.5530/ijpi.14.4.132Vol. 14, Issue 4 (2024)Background: 1,3,4-thiadiazole nucleus is a flexible nucleus. There are numerous biological activities showed by this nucleus. Anticancer, anthelmintic, antimicrobial, anti-inflammatory, antioxidant; anti-HIV, anti- tuber…
Original ArticlePublished: 27 Sep 2024
Srinaina Kapilavai, Ranganadha Reddy Aluru, Chandrasekhar Chanda
pp. 1216-1220 · DOI: 10.5530/ijpi.14.4.133Vol. 14, Issue 4 (2024)Objectives: Pectinase plays a crucial role in the commercial food processing industry by aiding in the breakdown of pectin and facilitating various processing stages like liquefaction, clarifying, and juice extraction. T…
Original ArticlePublished: 27 Sep 2024
Meriga Pramod Kumar, Shaik Amrin, Chenna Reddy Vaishnavi, Butti Swapna, Pullaganti Sai Charan, Leela Prasad
pp. 1221-1225 · DOI: 10.5530/ijpi.14.4.134Vol. 14, Issue 4 (2024)Background: The most prevalent infectious disorders are Urinary Tract Infections (UTI) and Respiratory Tract Infections (RTI), which are frequently related to morbidity and mortality. Due to improper antibiotic administr…
Original ArticlePublished: 27 Sep 2024
Ritu Saini, Meenakshi Bajpai
pp. 1226-1234 · DOI: 10.5530/ijpi.14.4.135Vol. 14, Issue 4 (2024)Background: Natural products such as plants and herbs are primely opted for by the consumers these days for the treatment or mitigation of any health condition. And countless options present in our surroundings, that can…
Original ArticlePublished: 27 Sep 2024
Nivetha Chitra Kandasamy, Sankar Veintramuthu, Ponpandian Nagamony, Justin Anthomy, Ramesh Santhanam, Jawahar Natarajan
pp. 1235-1241 · DOI: 10.5530/ijpi.14.4.136Vol. 14, Issue 4 (2024)Background: Cancer is the most lethal disease in humans, accounting for one out of every six fatalities. The most frequent type of cancer among women is breast cancer, followed by cervix cancer. Iron oxide nanoparticles,…
Original ArticlePublished: 27 Sep 2024
Sumitradevi Choudhary, K H Harish, Amruth M Sansthanmath, M Mahesh, Revati D Sagare, Fatima Sanjeri Dasankoppa, Agadi Hiremath Viswanatha Swamy
pp. 1242-1252 · DOI: 10.5530/ijpi.14.4.137Vol. 14, Issue 4 (2024)Aim and Objectives: The present work aimed to prepare a FDBF with a fixed dose of Doxylamine succinate. This film provides fast relief from sudden allergic reactions. Materials and Methods: FDBF were produced employing a…
Original ArticlePublished: 27 Sep 2024
Niusha Hassandoost, Mobina Fotuhi, Kethineni Chandrika, Davoud Balarak
pp. 1253-1259 · DOI: 10.5530/ijpi.14.4.138Vol. 14, Issue 4 (2024)Background: Antibiotics play a crucial role in the treatment of infectious diseases in humans and animals. However, their incomplete metabolism in the body often results in their release as active compounds into aquatic …
Original ArticlePublished: 27 Sep 2024
Abdulaziz Mohammed Asiri, Amer Ali Ahmad Al Ali, Mohammed Haidar Abu-Alghayth
pp. 1260-1272 · DOI: 10.5530/ijpi.14.4.139Vol. 14, Issue 4 (2024)Background: Breast cancer is the most commonly diagnosed cancer and the second most prominent cause of death in women. Owing to its intricate nature involving multiple cell types, preventing its onset is challenging. Tyr…
Original ArticlePublished: 27 Sep 2024
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Triveni Jagadish Umarani, Sai Meghana Gummadi
pp. 1273-1278 · DOI: 10.5530/ijpi.14.4.140Vol. 14, Issue 4 (2024)Background: Respiratory infections refer to any disease of airways and lungs which affects the respiratory system of humans. The nasal cavities, pharynx, larynx, trachea, bronchi and bronchioles, the tissues of the lungs…
Original ArticlePublished: 27 Sep 2024
Satish Karoli, M S Ganachari
pp. 1279-1286 · DOI: 10.5530/ijpi.14.4.141Vol. 14, Issue 4 (2024)Background: Improving outcomes for cancer patients, particularly older adults with complex health requirements, necessitates optimizing drug therapy. The Individualized Medication Assessment and Planning (iMAP) program, …
Case Report
Case ReportPublished: 27 Sep 2024
Guntur Prasanthi, Nagaraju Bandaru, Neredumilli Navya Sri, Swathi Nalla, Makarand Suresh Gambhire, Nallapaty Srilakshmi
pp. 1287-1290 · DOI: 10.5530/ijpi.14.4.142Vol. 14, Issue 4 (2024)Acute Generalized Exanthematous Pustulosis (AGEP) is a rare and severe cutaneous adverse reaction characterized by the abrupt onset of widespread sterile pustules on an erythematous base. This is associated with medicati…
Research Article
Research ArticlePublished: 27 Sep 2024
Zainab Eassa Jassim
pp. 1291-1298 · DOI: 10.5530/ijpi.14.4.143Vol. 14, Issue 4 (2024)Poorly soluble drugs are sources of concern in pharmaceutical formulations. Hydrotropes are compounds that enhance the solubility of insoluble materials in solvents. The hydrotropic solubilization concept is one of the m…
