International Journal of Pharmaceutical Investigation · Archive
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In this issue
21–33 of 33Original Article(continued)
Original ArticlePublished: 15 Dec 2023
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Lizanne Fernandes, Sadaf Sultana, Saurav Raj, Megha Hegde, Dhananjay Tikadar, Aju Alex, Raviteja Kanavi
pp. 165-171 · DOI: 10.5530/ijpi.14.1.21Vol. 14, Issue 1 (2023)Background: Postpartum Depression (PPD) is one of the least vocalized topics surrounding pregnancy and motherhood in India. The study aimed to assess the postpartum depression in women who had cesarean and normal vaginal…
Original ArticlePublished: 15 Dec 2023
Rohit Jaysing Bhor, Adesh Chandrakant Agale, Gaikwad Mayur Sitaram, More Dhanraj Navnath, Wayse Siddheshwar Sunil
pp. 172-179 · DOI: 10.5530/ijpi.14.1.22Vol. 14, Issue 1 (2023)Background: The serine/threonine kinase p38 Mitogen-Activated Protein (MAP) kinase is one of the most well studied kinases in the inflammatory process. The goal of this study was to see how a p38 MAP Kinase inhibitor (PD…
Original ArticlePublished: 15 Dec 2023
Jisha Mohanan, Gopinath Subramaniyan, Arul Kuttalingam, Damodharan Narayanasamy
pp. 180-185 · DOI: 10.5530/ijpi.14.1.23Vol. 14, Issue 1 (2023)Introduction: The study aimed to assess the bioavailability of two sublingual formulations i.e., fast-dissolving films and tablets of the poorly bioavailable immunosuppressant drug, tacrolimus, and to compare with its ma…
Original ArticlePublished: 15 Dec 2023
Aayushi Jaiswal, Mudumba Srivarshini, Patlolla Akshitha Reddy, Tripura Sundari, Sirisha Sunkavalli, Ramya Vandanasetti, Shaheen Begum, Arifa Begum SK
pp. 186-190 · DOI: 10.5530/ijpi.14.1.24Vol. 14, Issue 1 (2023)Background: The Levonorgestrel-releasing intrauterine system was inserted in patients with conditions like Abnormal Uterine Bleeding (AUB), adenomyosis and Perimenopausal Bleeding (PMB). This study aimed to find the effe…
Original ArticlePublished: 15 Dec 2023
Sandhya Murali, Prasanth Viswanadhan Vasantha
pp. 191-203 · DOI: 10.5530/ijpi.14.1.25Vol. 14, Issue 1 (2023)Purpose: This study aimed to prepare and evaluate mucoadhesive buccal patches of Sumatriptan Succinate (SUS) made from natural polymers to improve bioavailability, patient compliance, and dose-dependent adverse effects a…
Original ArticlePublished: 15 Dec 2023
Kalepu Eswar Krishna Sai, Medidi Srinivas, Bula Udaya Kumari, Chepyala Sumalatha, Arram Madhavi
pp. 204-211 · DOI: 10.5530/ijpi.14.1.26Vol. 14, Issue 1 (2023)Objectives: A straightforward, accurate, and precise reverse-phase high-performance liquid chromatography method was developed to determine the quantity of Lobeglitazone in both bulk and pharmaceutical dosage forms. Mate…
Original ArticlePublished: 15 Dec 2023
Tejas B Patel, Shantilal P Padhiyar, Vipul T Prajapati, Vashisith P Bhavsar, Nishit D. Patel, Dharmik A. Shah
pp. 212-224 · DOI: 10.5530/ijpi.14.1.27Vol. 14, Issue 1 (2023)Background: This research was conducted to create a treatment for osteoporosis (bone degenerating disorder) with hormone replacement therapy using Hydroxyapatites and chitosan as a composite. The research aims to develop…
Original ArticlePublished: 15 Dec 2023
Pravalika Mupparapu, Afra Azeenath, Tahsina Firdous, Tamanna Yeasmin, Mohd Azharuddin
pp. 225-231 · DOI: 10.5530/ijpi.14.1.28Vol. 14, Issue 1 (2023)Background: Diabetes is persistent illness that develops mostly when the body produces insufficient amount of the insulin hormone. The insulin hormone regulates blood glucose levels. In recent epidemiological research st…
Original ArticlePublished: 15 Dec 2023
Sanju Trizah Saji, Prasanth Viswanadhan Vasantha
pp. 232-238 · DOI: 10.5530/ijpi.14.1.29Vol. 14, Issue 1 (2023)Aim and Objectives: This study examined SSRI-related adverse drug reactions (ADRs), medication adherence, commonly prescribed SSRIs, and gender and age distribution in patients with depression at three tertiary care hosp…
Original ArticlePublished: 15 Dec 2023
Ayesha Naz, CVS Subrahmanyam, Shyam Sunder Rachamalla
pp. 239-249 · DOI: 10.5530/ijpi.14.1.30Vol. 14, Issue 1 (2023)Background: The present study aims to develop an Elementary Osmotic tablet (EOP) of Rivastigmine Hydrogen Tartrate (RHT). EOP consists of a core tablet suitably coated with a polymeric solution, and an orifice drilled on…
Original ArticlePublished: 15 Dec 2023
Anand Shripal Ammanage, Vinayak Shivamurthi Mastiholimath
pp. 250-257 · DOI: 10.5530/ijpi.14.1.31Vol. 14, Issue 1 (2023)Background: Diabetes is an endocrine disorder characterized by an abnormal increase in blood sugar level. Vildagliptin is a Dipeptidyl Peptidase-4 (DPP-4) inhibitor used in the treatment of type 2 diabetes mellitus. Purp…
Original ArticlePublished: 15 Dec 2023
Lekhana Bandi, Naga Shivani Lakshmisetty, Keerthana Ankireddy, Leela Lakshmi Vaishnavi Pulipati, Asritha Lakshmi Bontu, Ranganadha Reddy Aluru, Chandrasekhar Chanda
pp. 258-262 · DOI: 10.5530/ijpi.14.1.32Vol. 14, Issue 1 (2023)Objectives: Lipases are widely used in biodiesel, food, detergent, and pharmaceutical industries. To fulfil the rising demand for these crucial industrial enzymes, an extensive study on lipases from various micro-organis…
Case Report
Case ReportPublished: 15 Dec 2023
Megha Hegde, Saurav Raj, Anil Ashvil, Dhananjay Tikadar, Sanatkumar Bharamu Nyamagoud
pp. 263-267 · DOI: 10.5530/ijpi.14.1.33Vol. 14, Issue 1 (2023)Background: Toxic Epidermal Necrolysis (TEN), also known as Lyell's syndrome, is a rare but severe connective tissue condition that is a common cause of substantial skin damage as well as mucous membrane breakdown. This …