
International Journal of Pharmaceutical Investigation · Archive
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In this issue
21–38 of 38Original Article(continued)
Original ArticlePublished: 5 Jul 2023
Design, Optimization and Characterization of Newer Herbal Tablet Containing Momordica dioica Extract
Subhashchandra K. Patel, Hirenkumar R. Chaudhary, Tejal R. Gandhi
pp. 538-547 · DOI: 10.5530/ijpi.13.3.067Vol. 13, Issue 3 (2023)Background: Momordica dioica (MD) is called the teasle gourd, spiny gourd, and kakrol. Among the important phytochemicals present in MD include alkaloids, flavonoids, phenolics, tannins, saponins, steroids, glycosides, a…
Original ArticlePublished: 5 Jul 2023
Swati Rathore, Maadhu Reddemma, Neha Rai, Richa Tripathy Tiwari, Shaheen Begum, Shailendra Patil, Asmita Gajbhiye Patil
pp. 548-558 · DOI: 10.5530/ijpi.13.3.068Vol. 13, Issue 3 (2023)Background: Cancer is the world’s leading cause of death; more than ten million people die from cancer each year. Rate of morbidity and mortality is increasing day by day. As a result, utilizing chemoinformatics techniqu…
Original ArticlePublished: 5 Jul 2023
Sumit Shashikant Mude, Mukesh Tatyarao Mohite
pp. 559-565 · DOI: 10.5530/ijpi.13.3.069Vol. 13, Issue 3 (2023)Purpose: In the last decade over 17.46 million people in India died due to wrong medication and drug-drug interaction. In fact, Drug-drug interaction is the 4th leading cause of death in India. Medications used in COVID-…
Original ArticlePublished: 5 Jul 2023
Neha Rai, Swati Rathore, Richa Tripathy Tiwari, Shailendra Patil, Asmita Gajbhiye
pp. 566-573 · DOI: 10.5530/ijpi.13.3.070Vol. 13, Issue 3 (2023)Background: The biological compounds known as peptides are found in nature. They are peptide (amide) links that connect short chains of amino acid monomers. Nowadays, peptide-based therapeutic treatments are employed bec…
Original ArticlePublished: 5 Jul 2023
Aishwarya Ramchandra Balap, Aniket Padmakant Dudhe
pp. 574-581 · DOI: 10.5530/ijpi.13.3.071Vol. 13, Issue 3 (2023)Introduction: Favipiravir was remerging antiviral drug in the beginning era of COVID-19 Pandemic as an urgent therapeutic alternative to treat COVID-19. Literature survey reveals that there is no any reported stability i…
Original ArticlePublished: 5 Jul 2023
Atul Baravkar, Gandhi Santosh, Bawaskar Namrata, Vitthal Chopade, Makarand Puri, Vishnu Neharkar, Ramdas Kale, Dattatray Kature, Rahul Jadhav, Manisha Patil, Reshma Devkate, Alfa Jain, Deepali Kadam, Amol Khedkar, Sachin Vijapure, Nilima Wani, Ganesh Shinde
pp. 582-587 · DOI: 10.5530/ijpi.13.3.072Vol. 13, Issue 3 (2023)Background: Cramer's rule is one of the significant techniques applied to settle an arrangement of conditions. In this rule, the upsides of the factors in the framework are to be determined utilizing the determinants of …
Original ArticlePublished: 5 Jul 2023
Hitesh G. Raval, Ujashkumar A. Shah, Hirak Kumar Joshi, Vaishali T. Thakkar
pp. 588-594 · DOI: 10.5530/ijpi.13.3.073Vol. 13, Issue 3 (2023)Objectives: Fluconazole (FCZ) and Quercetin (QCT) in pharmaceutical dosage form were simultaneously quantified using a sensitive, accurate, robust, and précised Reverse Phase-HPLC Method. Materials and Methods: RP-HPLC m…
Original ArticlePublished: 5 Jul 2023
Aarthi Kommu, Raja Sundararajan
pp. 595-604 · DOI: 10.5530/ijpi.13.3.074Vol. 13, Issue 3 (2023)Objectives: For the quantification of rivastigmine in both its pure form and pharmaceutical formulation, an ultra-performance liquid chromatography method with high speed and sensitivity was created and validated. Materi…
Original ArticlePublished: 5 Jul 2023
B.M. Gupta, K.K. Mueen Ahmed, Mallikarjun M Kappi, Madhu Bansal, Jivesh Bansal
pp. 605-616 · DOI: 10.5530/ijpi.13.3.075Vol. 13, Issue 3 (2023)Background and Aim: The coronavirus disease 2019 (COVID-19) virus pandemic is still ravaging the world with its ongoing resurgence and continuous mutation, suggesting the need for continuous research on safe and effectiv…
Original ArticlePublished: 5 Jul 2023
Gaddam Venkata Abhigna, Raja Sundararajan
pp. 617-624 · DOI: 10.5530/ijpi.13.3.076Vol. 13, Issue 3 (2023)Objectives: A novel, precise, and accurate RP-HPLC method was developed and validated for the determination of valganciclovir in pure and medicinal dose form. Cytomegalovirus infections were treated with the antiviral me…
Original ArticlePublished: 5 Jul 2023
Manouchehr Khanipour, Mina Shahraki Mohammadi, Balakeshwa Ramaiah
pp. 625-631 · DOI: 10.5530/ijpi.13.3.077Vol. 13, Issue 3 (2023)Introduction: Antibiotics have important roles in human health, whereas irrational use of antibiotics is a major problem of public health that leads to resistance and ADRs. This study aimed to evaluate the prescribing pa…
Original ArticlePublished: 5 Jul 2023
Uppara Veerendra, Palagiri Akbar Basha, Byragani Naga Bindu, Deti Pruthvi Bhushan, Gutam Venkata Kalyani
pp. 632-640 · DOI: 10.5530/ijpi.13.3.078Vol. 13, Issue 3 (2023)Introduction: Musculoskeletal disorders are injuries or illnesses that affect the muscles, nerves, tendons, joints, cartilage, and spinal discs. These disorders are characterized by a loss of physical function in the bod…
Original ArticlePublished: 5 Jul 2023
Kommanuru Venkata Ramakrishna Teja, Yiragamreddy Padmanabha Reddy, Nayakanti Devanna
pp. 641-645 · DOI: 10.5530/ijpi.13.3.079Vol. 13, Issue 3 (2023)Introduction: Although adverse drug reaction (ADR) monitoring is widely known, it is not practised in underdeveloped nations due to a lack of awareness and the absence of a central coordinating agency. The recent impleme…
Original ArticlePublished: 5 Jul 2023
Glara Anest Francis, Sureka Arumugam, Sabari Girija Navaneetha Krishnan, Ramamurthy Murugan, Christian Gnanaraj Johnson, Moses Erin Johnson Christian, Meenakumari Ramasamy
pp. 646-650 · DOI: 10.5530/ijpi.13.3.080Vol. 13, Issue 3 (2023)Introduction: Ovarian cancer is the fifth most common cause of cancer which causes more deaths than any other cancer of the female reproductive system because there is no effective screening and most women are diagnosed …
Original ArticlePublished: 5 Jul 2023
Harish Gupta, Girendra Kumar Gautam
pp. 651-655 · DOI: 10.5530/ijpi.13.3.081Vol. 13, Issue 3 (2023)The present study is designed to evaluate the phytochemical profile of Elaeocarpus ganitrus and Desmostachya bipinnata. Extraction was performed using ethanol as a solvent for both the plants. Preliminary phytochemical s…
Original ArticlePublished: 5 Jul 2023
Sanjay U Nipanikar, Pravin S Surwade, Ankita R Kasabe, Priyanka B Patil, Sachin A Upasani
pp. 656-665 · DOI: 10.5530/ijpi.13.3.082Vol. 13, Issue 3 (2023)Introduction: A simple, accurate, precise, sensitive, and validated RP-HPLC method was developed for simultaneous estimation of Gallic Acid (GA), Vasicine (VS), Pterostilbene (PTS) and Piperine (PP) from Ayurvedic Propri…
Original ArticlePublished: 5 Jul 2023
Shweta Vashist, Manoj M. Gadewar
pp. 666-672 · DOI: 10.5530/ijpi.13.3.083Vol. 13, Issue 3 (2023)Aim: Oral mucositis is a problem which is found in a cancer patient, taking chemotherapy radiation therapy. This work aims to formulate a mucoadhesive curcumin proniosomal gel by using thiolated chitosan for buccal deliv…
Original ArticlePublished: 5 Jul 2023
Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Viswanatha Swamy, Bharati Kangrali
pp. 673-679 · DOI: 10.5530/ijpi.13.3.084Vol. 13, Issue 3 (2023)Background: Diabetes Mellitus (DM) is a chronic metabolic condition characterized by high blood glucose levels and changes in carbohydrate, lipid and protein metabolism due to insulin secretion, action, or both.1 Diabete…
