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International Journal of Pharmaceutical Investigation

Volume 16, Issue 2

2026 · pp. 371–769 · 43 articles

Volume
16
Issue
2
Year
2026
Published
2 Feb 2026
Pages
371–769
Articles
43
Sections
2
ISSN
2230-9713
Journal
IJPI

In this issue

1–20 of 43

Review Article

  1. Review ArticlePublished: 2 Feb 2026

    Mary Brenda Ogwang, Deepak Kumar Jha, Sandipan Chatterjee

    pp. 371-383Vol. 16, Issue 2 (2026)
  2. Review ArticlePublished: 2 Feb 2026

    Vaishnavi N. Thute, Sukeshini Lote

    pp. 384-397 · DOI: 10.5530/ijpi.20260274Vol. 16, Issue 2 (2026)

    The process of drug discovery is slowly entering the era of change, wherein more efficient and effective approaches to identify the potential therapeutic compounds are sought. This review article explores the future of d…

  3. Review ArticlePublished: 2 Feb 2026

    Arige Sirisha, Rama Rao Vadapalli, Penmatsa Srinidhi, Bathula Mahalakshmi, Muchakarla Sri Yagna, Kanuri Teja, T. Sowmya Sri

    pp. 398-404 · DOI: 10.5530/ijpi.20260341Vol. 16, Issue 2 (2026)

    Cancer is the most leading cause of the death. Only few treatment options are available for treating the cancer such as radiation therapy, chemotherapy, and surgery. These treatment options can either used as single or c…

  4. Review ArticlePublished: 2 Feb 2026

    Thalal Mohamed, Srimathi Mahadevan, Jayashri Vidya Prabhakaran, Sundari Venkatesan, Mohammed Fayaz, Vijayakumar Thangavel Mahalingam

    pp. 405-413 · DOI: 10.5530/ijpi.20260349Vol. 16, Issue 2 (2026)

    Tirzepatide is redefining the treatment landscape for metabolic and non-metabolic disorders. By uniquely harnessing two critical hormonal pathways, the review provides comprehensive insights into how Tirzepatide’s dual m…

  5. Review ArticlePublished: 2 Feb 2026

    Harshith Naganna, Kumble Prakash Rao Tejas Rao, Tejaswi Hiremarali Lokanathan, Mathada Vamadevaiah Ravishankar

    pp. 414-424 · DOI: 10.5530/ijpi.20260360Vol. 16, Issue 2 (2026)

    Plastic is found with its wide applications worldwide to fulfil our domestic and industrial needs. Its vast diversified usability and unscientific disposal patterns cause tireless accumulation of various forms of plastic…

  6. Review ArticlePublished: 2 Feb 2026

    Kirtimaya Mishra, Asra Jabeen, Swetha Vegesna, Gowri Sankar Chintapalli, Debasis Patra, Diptimayee Jena

    pp. 425-430 · DOI: 10.5530/ijpi.20260373Vol. 16, Issue 2 (2026)

    Mouth Dissolving Tablets (MDTs) are considered as a novel approach to improvize patient compliance and fast drug delivery. They constitute a significant improvement in pharmaceutical technology. The dissertation explores…

  7. Review ArticlePublished: 2 Feb 2026

    Niyati Shah, Ritu Sapra, Maitry Suthar, Piyushkumar Sadhu, Nisha Mandloi, Mamta Kumari, Chitrali Talele, Chintan Aundhia

    pp. 431-441 · DOI: 10.5530/ijpi.20260010Vol. 16, Issue 2 (2026)

    Breast cancer remains a significant global health challenge, necessitating innovative therapeutic approaches to improve patient outcomes. Drug delivery systems have emerged as promising tools to enhance the efficacy and …

  8. Review ArticlePublished: 2 Feb 2026

    Kalyani Andraskar, Krishna Raj, Abhay Tiwary, Poonam Lal

    pp. 442-449 · DOI: 10.5530/ijpi.20260430Vol. 16, Issue 2 (2026)

    Nanoparticles of Titanium Dioxide (TiO₂) have also become an essential element of nanomedicine because of their multifunctionality and wide use in medicine. This review compiles current advances in the synthesis, functio…

  9. Review ArticlePublished: 2 Feb 2026

    Mayur Rajeshwar Dandekar, Isha anil Mirzapure, Yash Manoj Salve, Deepak Khobragade

    pp. 450-461 · DOI: 10.5530/ijpi.20260432Vol. 16, Issue 2 (2026)

    Real-time release Testing is now considered one of the breakthroughs in pharmaceutical quality control, replacing the old batch-testing paradigms with a modern, real-time, more efficient, data-driven approach. RTRT combi…

  10. Review ArticlePublished: 2 Feb 2026

    Mayur Dandekar, Deepak khobragade, Yash Salve, Sakshi Mandhane, Isha Mirzapure

    pp. 462-469 · DOI: 10.5530/ijpi.20260480Vol. 16, Issue 2 (2026)

    The importance of GMP audits in ensuring the quality, safety, and efficacy of pharmaceuticals is unmistakable. These audits are systematic appraisals of facilities, processes, personnel, documentation, and quality manage…

  11. Review ArticlePublished: 2 Feb 2026

    Shweta Bhandari, Rahul Trivedi, Rajesh Hadia, Ajay kumar Saini, Vishal Garg, Ram Singh

    pp. 470-475 · DOI: 10.5530/ijpi.20260588Vol. 16, Issue 2 (2026)

    Vaccines have saved millions of lives and reduced the spread of infectious diseases, thereby transforming global health. This comprehensive overview traces the historical evolution of vaccines-from ancient inoculation pr…

  12. Review ArticlePublished: 2 Feb 2026

    Mohammed Tarique, Ziaullah Sain, Yusuf Ahmad

    pp. 476-489 · DOI: 10.5530/ijpi.20260154Vol. 16, Issue 2 (2026)

    Malaria, which is caused by Plasmodium parasites, remains a major international health issue, especially in developing countries. The problem of drug resistance has become a major concern, especially with respect to arte…

  13. Review ArticlePublished: 2 Feb 2026

    Rohit Bairagi, Ruchi Suryawanshi, Suankit Harane, Milind Umekar, Vinita Kale

    pp. 490-499 · DOI: 10.5530/ijpi.20260578Vol. 16, Issue 2 (2026)

    Juvenile Animal toxicity Studies (JAS) are conducted to evaluate potential safety risks, particularly those affecting postnatal growth and development, that may not be detectable through standard toxicity studies or pedi…

  14. Review ArticlePublished: 2 Feb 2026

    M Varsha, Sarumathy Sundararajan

    pp. 500-506 · DOI: 10.5530/ijpi.20260065Vol. 16, Issue 2 (2026)

    L-Carnitine, a naturally occurring quaternary amine, plays a crucial role in mitochondrial fatty acid transport and energy metabolism. This narrative review explores the pharmacological significance of L-Carnitine in rep…

  15. Review ArticlePublished: 2 Feb 2026

    Blessy K George, Jaidev Kumar, Sunil Kumar, Balakeshaw Ramaiah

    pp. 507-516 · DOI: 10.5530/ijpi.20260514Vol. 16, Issue 2 (2026)

    This review article on utilization and regulations of OTC drugs aims to highlight the significance of establishing legal policies on "OTC medicines" in India by outlining the potentially harmful effects of these medicati…

  16. Review ArticlePublished: 2 Feb 2026

    Yogita Shinde, Tanishka Prakash Sharma, Archana Shaha, Rakesh Chaudhari, Rashmi Rajeghorpade, Dipali Talele, Chitrali Talele

    pp. 517-522 · DOI: 10.5530/ijpi.20260539Vol. 16, Issue 2 (2026)

    Messenger RNA (mRNA) therapies are a groundbreaking treatment for various conditions, including infectious diseases, cancer, and genetic disorders. This review examines the processing of mRNA therapeutics in the body, fo…

  17. Review ArticlePublished: 2 Feb 2026

    Qamre Alam, Reem Saeed Alazragi, Alaa Al-Kathiri, Alrayan Abass Albaz, Jawaher Mohammad Alshehri, Fatimah Ali Alsaffar, Dalia Alammari, Saleh Alqahtani

    pp. 523-535 · DOI: 10.5530/ijpi.20260153Vol. 16, Issue 2 (2026)

    This review thoroughly examines Breast Cancer Stem Cells (BCSCs) discussing their involvement, in tumor advancement and spread and their resistance to treatment while also discussing methods for targeting them for elimin…

  18. Review ArticlePublished: 2 Feb 2026

    Santosh Kumar Dash, Ashutosh Padhan, Abdul Sayeed Khan, Tusara Kanta Behera, Sachhidananda Mohapatra, Sulagna Parta, Ranjan Kumar Sahoo

    pp. 536-540 · DOI: 10.5530/ijpi.20260109Vol. 16, Issue 2 (2026)

    Cancer remains a leading cause of global mortality. Conventional treatments such as chemotherapy, radiation, and surgery often lead to severe side effects and limited effectiveness. Nanoparticulate Drug Delivery Systems …

  19. Review ArticlePublished: 2 Feb 2026

    Arya Deshmukh, Mujibullah Sheikh, Akanksha Dange

    pp. 541-560 · DOI: 10.5530/ijpi.20260081Vol. 16, Issue 2 (2026)

    Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by deficits in social interaction and communication alongside repetitive behaviors and restricted interests. Despite substantia…

  20. Review ArticlePublished: 2 Feb 2026

    Nandula Lavanya, Rashmi Nelligare Gopalakrishna

    pp. 561-568 · DOI: 10.5530/ijpi.20260469Vol. 16, Issue 2 (2026)

    Advancements in drug development emphasize enhancing efficacy, reducing side effects, and tailoring treatments to individual patient needs. Conventional antidepressant therapies often face limitations such as delayed ons…