International Journal of Pharmaceutical Investigation
Volume 16, Issue 1
2025 · pp. 1–370 · 40 articles
- Volume
- 16
- Issue
- 1
- Year
- 2025
- Published
- 23 Oct 2025
- Pages
- 1–370
- Articles
- 40
- Sections
- 3
- ISSN
- 2230-9713
- Journal
- IJPI
In this issue
1–20 of 40Review Article
Review ArticlePublished: 23 Oct 2025
Oyitabu Ifunanya Mercy, Vemula Kusum Devi, Vijaya Gopalachar Joshi, Gagana Dhanalakshma Nayaka, Urmila Gurupadhaya Hiremath, Malviya Nidhi, Priyanka Nandibasappa, Rama Bukka, Rama Radhakrishna Nargund, Shravan Laxmivenkatesh Nargund, Shachindra Laxmivenkatesh Nargund
pp. 1-11 · DOI: 10.5530/ijpi.20260415Vol. 16, Issue 1 (2025)Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of dopaminergic neurons and the presence of Lewy body pathology. Its prevalence increases with age, affecting approxi…
Review ArticlePublished: 23 Oct 2025
Lakshmi Prasanthi Nori, Chintakrindi Parvesh, Akshaya Ratna Kireeti, Jyothika Chittala, Lavanya Chintalapati, Kudeti Himaja Kasturi, Kalidindi Venkateswara Raju
pp. 12-22 · DOI: 10.5530/ijpi.20260001Vol. 16, Issue 1 (2025)The integration of nanomedicine with personalized medicine represents a transformative paradigm in healthcare, significantly enhancing the diagnosis, treatment, and prevention of diseases. However, the regulatory framewo…
Review ArticlePublished: 23 Oct 2025
Sandeep Talari, Vivek Reddy Murthannagari, Gundavarapu Kanaka Phani Kumar, Gowthamarajan Kuppusamy, Srikanth Jupudi
pp. 23-29 · DOI: 10.5530/ijpi.20260314Vol. 16, Issue 1 (2025)In healthcare, adaptive AI and machine learning offer continuous performance improvement through patient data updates, but traditional regulation methods are slow and cumbersome. The USFDA and EMEA propose a paradigm shi…
Review ArticlePublished: 23 Oct 2025
Jehath Syed, Christy Thomas, Bavneet Kaur, Prathibha Pereira, Tejaswini Chittanahalli Jayaram, Krishna Undela, Ramesh Madhan, Pramod Kumar Teggina Math, Vikarm Patil, Shilpa Avarebeel, Kshama Ramesh, Sri Harsha Chalasani
pp. 30-42 · DOI: 10.5530/ijpi.20260506Vol. 16, Issue 1 (2025)Drug-Related Problems (DRPs) are common among hospitalized older adult patients and can lead longer hospital stays, worsening clinical conditions, increased healthcare costs, and even death. Artificial Intelligence (AI)-…
Review ArticlePublished: 23 Oct 2025
Vishal Sachan, Tanveer Naved, Ajay Sachan, Yamini Kohli
pp. 43-50 · DOI: 10.5530/ijpi.20260343Vol. 16, Issue 1 (2025)Background: The criminal offences under the Drugs and Cosmetics Act, 1940 (DCA) directly affect the life of people in India. As per statute, it is obligatory for Drugs Inspector to conduct investigation and execute furth…
Review ArticlePublished: 23 Oct 2025
Soiba Siddiqui, Madhan Ramesh, Prashanth Sathya Narayana
pp. 51-57 · DOI: 10.5530/ijpi.20260414Vol. 16, Issue 1 (2025)The integration of digital surveillance and Artificial Intelligence (AI) technology constitutes a significant shift in Adverse Event Following Immunization (AEFI) monitoring. This review explores the artificial intellige…
Review ArticlePublished: 23 Oct 2025
Satya Obbalareddy, Anubhav Dubey, Mamta Kumari, Chandan Mukherjee, Sanyogita Shahi, Sayantan Dutta
pp. 58-65 · DOI: 10.5530/ijpi.20260462Vol. 16, Issue 1 (2025)Nearly 70% of the population will be infected with Human Papillomavirus (HPV) at some point in their lives; in India, 27,526 women are diagnosed with the virus each year, and 79,906 lose their lives to it. Research has l…
Review ArticlePublished: 23 Oct 2025
Ruchi Tiwari, Priyanka Shukla, Gaurav Tiwari, Mahesh Kumar Posa, Mallikarjun Mugli, Anurag Mishra
pp. 66-76 · DOI: 10.5530/ijpi.20260447Vol. 16, Issue 1 (2025)A biopolymer is a naturally derived polymer, obtained from living organisms like plants, animals and various microorganism. The biopolymer is made up of various monomer units which are linked together with each other thr…
Review ArticlePublished: 23 Oct 2025
Paramita Ganguly, Puja Saha, Sourav Khawas, Sandip Chatterjee, Arvind Kumar Patel, Prangyan Paramita Pati
pp. 77-88 · DOI: 10.5530/ijpi.20260499Vol. 16, Issue 1 (2025)Microneedles, first introduced in 1976, address these limitations by creating tiny, non-invasive channels that enhance drug penetration through the skin. Transdermal Drug Delivery (TDD) is a less intrusive approach that …
Review ArticlePublished: 23 Oct 2025
Mamatha Gavisiddaiah, Kenganora Mruthunjaya, Santhepete Nanjundaiah Manjula
pp. 89-97 · DOI: 10.5530/ijpi.20260338Vol. 16, Issue 1 (2025)Alzheimer's Disease (AD), characterised by cognitive impairment and memory loss, is primarily caused by the deterioration of the central nervous system, which is a vital component of the human body. Amyloid-beta plaque b…
Review ArticlePublished: 23 Oct 2025
Kirtimaya Mishra, Asra Jabeen, Sarojini Nayak, Ritupriya Mohanty, Debasis Patra, Diptimayee Jena
pp. 98-104 · DOI: 10.5530/ijpi.20260472Vol. 16, Issue 1 (2025)The sustainable substitute for conventional nanomaterials, Plant-Derived Nanoparticles (PDNPs), employ green synthesis techniques to reduce their negative effects on the environment while increasing their medicinal effec…
Review ArticlePublished: 23 Oct 2025
N Amitha, DS Sandeep, P Rajanikant, MP Gowrav, S Kathirvel, HK Pradeep, MR Jeyaprakash
pp. 105-110 · DOI: 10.5530/ijpi.20260359Vol. 16, Issue 1 (2025)Cubosomes are self-assembled nanostructures that exhibit a bicontinuous cubic phase. These nanoparticles can incorporate many drugs, including amphiphilic, hydrophilic, and lipophilic substances. The structure of cubosom…
Review ArticlePublished: 23 Oct 2025
Chinna Reddy Palem, Ravinder Rendla, Vamshi Krishna Lekkala, Neha Andhi, Nishant Kumar Nagamalli, Deepthi Battula, Sridhar Gumudevelli
pp. 111-122 · DOI: 10.5530/ijpi.20260433Vol. 16, Issue 1 (2025)Oral transmucosal drug delivery systems represent an innovative approach for the administration of therapeutic agents through the mucosal membranes, such as sublingual and buccal membranes in the mouth, offering advantag…
Original Article
Original ArticlePublished: 23 Oct 2025
S K Kavitha, Mohammad Ali
pp. 123-132 · DOI: 10.5530/ijpi.20260573Vol. 16, Issue 1 (2025)Background: To assess in vivo antidepressant of Ethanolic extract of Albizzia lebbeck (L.) own their family Fabaceae the plant's primary constituents Triterpenes, glycosides, saponins, flavonoids, and indole alkaloids ar…
Original ArticlePublished: 23 Oct 2025
Payal Shah, Gaurang Shah
pp. 133-142 · DOI: 10.5530/ijpi.20260444Vol. 16, Issue 1 (2025)Background: Reactive oxygen species (ROS), produced by different enzymes, play a role in oxidative stress, which is linked to the development of many diseases. The NADPH oxidase (NOX) enzyme family serves as a primary so…
Original ArticlePublished: 23 Oct 2025
Anushree Shrikant Deshpande, Madiwalayya Shivakantayya Ganachari
pp. 143-154 · DOI: 10.5530/ijpi.20260494Vol. 16, Issue 1 (2025)Background: Diabetes Mellitus (DM) is a serious worldwide health challenge, currently affecting over 425 million people globally. India bears a significant burden, with approximately 74 million diagnosed cases as of 2021…
Original ArticlePublished: 23 Oct 2025
Vinod Ashokdas Bairagi, Deepak Balasaheb Somavanshi, Yogesh Suresh Ahire, Jayashri Sanjay Nikam, Swapnil Bandu Jadhav, Mohammed Saad Abdul Hameed, Chandrashekhar Dinkar Patil, Amol Mohan Shirode, Mohammad Ikrama
pp. 155-166Vol. 16, Issue 1 (2025)Background: The discovery of efficacious anti-stress therapies is imperative, as chronic stress plays a substantial role in the development of numerous physical and mental health issues. Materials and Methods: The presen…
Original ArticlePublished: 23 Oct 2025
Kishori Prasanna Sutar, Sunil Satyappa Jalalpure
pp. 167-173 · DOI: 10.5530/ijpi.20260513Vol. 16, Issue 1 (2025)Background: The proposed study focuses on developing and validating a sensitive and simple UV-spectroscopic technique for apremilast quantification in bulk drug, commercial tablet, cubosomes and transferosomes. Materials…
Original ArticlePublished: 23 Oct 2025
Pruthviraj Vijay Kute, Rohit Jaysing Bhor, Mahesh Hari Kolhe, Harshada Shubhash Bhosale, Pornima Ramdas Tambe, Mayuri Rajesh Bhoknal, Pratibha Shankar Jadhav, Swapnali Baban Avhad, Mayuri Girish Dharam, Ajay Sanjay Mule
pp. 174-183 · DOI: 10.5530/ijpi.20260361Vol. 16, Issue 1 (2025)Background: The computational study of benzimidazole derivatives is the main topic of this article. All compounds' cytotoxicity against inflammation was assessed, and the outcomes showed that several of them had strong i…
Original ArticlePublished: 23 Oct 2025
Suresh Kumar Thirumoorthi, Rama Prabha Mani
pp. 184-192 · DOI: 10.5530/ijpi.20260303Vol. 16, Issue 1 (2025)Objectives: The study was aimed to investigate the presences of bioactive components by Debregeasia longifolia through Gas Chromatography-Mass Spectrometry (GC-MS) analysis and evaluate its in vitro free radical scavengi…