Volume 7, Issue 4

Original Research Article

1. Original Research Article|Published: 6 Dec 2017

   Lipid nanocapsules formulation and cellular activities evaluation of a promising anticancer agent: EAPB0503

   Adrien Chouchou, Anne Aubert‑Pouëssel, Christophe Dorandeu, Zahraa Zghaib, Pierre Cuq, Jean‑Marie Devoisselle, Pierre‑Antoine Bonnet, Sylvie Bégu, Carine Deleuze‑Masquefa

   pp. 155-163 · DOI: 10.4103/jphi.JPHI_53_17Vol. 7, Issue 4 (2017)

   Objectives: EAPB0503, lead compound of imiqualines, presented high antitumor activities but also a very low water solubility which was critical for further preclinical studies. To apply to EAPB0503, a robust and safe lip…

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2. Original Research Article|Published: 6 Dec 2017

   Formulation of cilostazol spherical agglomerates by crystallo‑co‑agglomeration technique and optimization using design of experimentation

   Sanjeevani Shekhar Deshkar, Govind R. Borde, Rupali N. Kale, Balasaheb A. Waghmare, Asha Biju Thomas

   pp. 164-173 · DOI: 10.4103/jphi.JPHI_39_17Vol. 7, Issue 4 (2017)

   Introduction: Spherical agglomeration is one of the novel techniques for improvement of flow and dissolution properties of drugs. Cilostazol is a biopharmaceutics classification system Class II drug with poor solubility …

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3. Original Research Article|Published: 6 Dec 2017

   Aminopropyl groups of the functionalized Mobil Crystalline Material 41 as a carrier for controlled diclofenac sodium and piroxicam delivery

   Elham Khodaverdi, Mina Ahmadi, Hossein Kamali, Farzin Hadizadeh

   pp. 174-181 · DOI: 10.4103/jphi.JPHI_77_17Vol. 7, Issue 4 (2017)

   Objectives: Synthetic Mobil Crystalline Material 41 (MCM‑41) as a mesoporous material and functionalized MCM‑41 using aminopropyl groups were studied in order to investigate their ability to encapsulate and to control th…

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4. Original Research Article|Published: 6 Dec 2017

   Drug information center as referral service in a South Indian tertiary care hospital

   Sapan Kumar Behera, Alphienes Stanley Xavier, Vikneswaran Gunaseelan, Byrappa Kempalalakshmamma Ravindra, Sandhiya Selvarajan, Adithan Chandrasekaran, Steven Aibor Dkhar

   pp. 182-187 · DOI: 10.4103/jphi.JPHI_90_17Vol. 7, Issue 4 (2017)

   Objectives: The objective of this study is to assess the various aspects of drug information services (DISs) provided in the DI center of a tertiary care hospital. Materials and Methods: DI queries received from various …

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5. Original Research Article|Published: 6 Dec 2017

   Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients

   P. L. Ravishankar, Y. Pradeep Kumar, E. N. Anila, Priyankar Chakraborty, Maharshi Malakar, R. Mahalakshmi

   pp. 188-192 · DOI: 10.4103/jphi.JPHI_82_17Vol. 7, Issue 4 (2017)

   Objectives: The objective of this study is to evaluate the comparative effect of curcumin and ornidazole in treating chronic periodontitis. Materials and Methods: Twenty individuals of both sexes aged between 27 and 53 y…

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6. Original Research Article|Published: 6 Dec 2017

   An assessment of reported adverse drug reactions in a Tertiary Care Hospital in South India: A retrospective cross‑sectional study

   Sandeep Kumar Gupta, K. Deva Kumar

   pp. 193-197 · DOI: 10.4103/jphi.JPHI_81_17Vol. 7, Issue 4 (2017)

   Objectives: The primary objective of this study was to assess the causality of ADRs using World Health Organization‑Uppsala Monitoring Centre (WHO–UMC), Naranjo and Liverpool ADR Causality Assessment Tool (LCAT). Other p…

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7. Original Research Article|Published: 6 Dec 2017

   Erratum: Development of a binary carrier system consisting polyethylene glycol 4000 ‑ ethyl cellulose for ibuprofen solid dispersion

   pp. 198 · DOI: 10.4103/2230-973X.229440Vol. 7, Issue 4 (2017)

   In the article titled “Development of a binary carrier system consisting polyethylene glycol 4000 ‑ ethyl cellulose for ibuprofen solid dispersion”, published on pages 142-148, Issue 3, Volume 7 of International Journal …

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