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International Journal of Pharmaceutical Investigation

Volume 16, Issue 4

2026 · pp. 1202–1724 · 50 articles

Volume
16
Issue
4
Year
2026
Published
18 Aug 2026
Pages
1202–1724
Articles
50
Sections
2
ISSN
2230-9713
Journal
IJPI

In this issue

41–50 of 50

Original Article(continued)

  1. Original ArticlePublished: 18 Aug 2026

    Magesh Mohan, Renukadevi Jeyavelkumaran, Sanjay Valliappan, Shakthi Harikrishnan, Kadir Aravindan, Balaji Ravikuma

    pp. 1601-1621 · DOI: 10.5530/ijpi.20260291Vol. 16, Issue 4 (2026)

    Background: Breast cancer progression is governed by highly interconnected signaling networks involving receptor tyrosine kinases and hormone-responsive nuclear receptors, which collectively drive tumor heterogeneity, ad…

  2. Original ArticlePublished: 18 Aug 2026

    Md. Zeyaullah, Kamal Ahmad

    pp. 1622-1628 · DOI: 10.5530/ijpi.20260014Vol. 16, Issue 4 (2026)

    Background: This study evaluates COVID-19 vaccination coverage, vaccine effectiveness against SARS-CoV-2 variants, and associated health consequences in the five most important Indian metropolitan cities: Delhi, Mumbai, …

  3. Original ArticlePublished: 18 Aug 2026

    Krutika Lolsure, Vijay Kumbar, Priya Shetti, Mitali Kubade, Malleswara Peram

    pp. 1629-1634 · DOI: 10.5530/ijpi.20260016Vol. 16, Issue 4 (2026)

    Introduction: Glioblastoma multiforme, an extremely aggressive form of brain cancer, presents significant challenges in treatment, despite the application of surgical intervention, radiation therapy, and chemotherapy. Re…

  4. Original ArticlePublished: 18 Aug 2026

    Sruthi Sai Kaveripakam, Sreedevi Adikay, Sowmya Venkata Donthamsetty, Surekha Lakshmi Khandavilli

    pp. 1635-1641 · DOI: 10.5530/ijpi.20260025Vol. 16, Issue 4 (2026)

    Background: Phytochemicals exhibit diverse therapeutic properties with minimal adverse effects and documented their benefits against metabolic disorders. Inhibition of pancreatic lipase is a validated strategy for managi…

  5. Original ArticlePublished: 18 Aug 2026

    Tahani Bakhsh

    pp. 1642-1656 · DOI: 10.5530/ijpi.20260058Vol. 16, Issue 4 (2026)

    Background: MDM2 is an E3 ubiquitin ligase that suppresses p53, promotes its degradation, inhibits apoptosis, and drives uncontrolled cancer cell growth. Targeting the MDM2-p53 interaction is therefore a promising strate…

  6. Original ArticlePublished: 18 Aug 2026

    K. K Mueen Ahmed, M Chaman Sab, Mohammed Yunus, Shery Jacob, Jigar N. Shah, Hiral J. Shah, Mahesh Attimarad, Sreeharsha Nagaraja, Rashed M. Almuqbil, Bandar E. Al-Dhubiab, Katharigatta N. Venugopala, Abdullah M. Alotaibi, Ahmed S. Alnaim

    pp. 1657-1665 · DOI: 10.5530/ijpi.20260004Vol. 16, Issue 4 (2026)

    Objective: Drug delivery and pharmaceutical-analysis research spans a wide range of sub-disciplines - nanocarrier formulation, transdermal and iontophoretic delivery, analytical method development, and computational drug…

  7. Original ArticlePublished: 18 Aug 2026

    Jahanvi Patel, Tejal Mehta

    pp. 1666-1679 · DOI: 10.5530/ijpi.20260292Vol. 16, Issue 4 (2026)

    Background: The primary objective of this study was to develop, optimize and evaluate a paediatric-friendly, pullulan-based Mouth Dissolving Film (MDF) of Ferrous Bisglycinate as a novel iron delivery system. The work ai…

  8. Original ArticlePublished: 18 Aug 2026

    S. Revathy, K. Shoba, A. Vidhya

    pp. 1680-1695 · DOI: 10.5530/ijpi.20260024Vol. 16, Issue 4 (2026)

    Background: Trigonella foenum-graecum (fenugreek) is a widely utilized medicinal herb known for its therapeutic potential in managing metabolic disorders. This study aimed to extract and characterise the bioactive consti…

  9. Original ArticlePublished: 18 Aug 2026

    Sanket Keshav Tambe, Rohit Jaysing Bhor, Sagar Dattatray Magar, Mayur Shivaji Bhosale, Shubham Popatrao Mankar, Datta Macchindra Abhale, Sachin Tukaram chavan, Gaurav Subhash Damre

    pp. 1696-1718 · DOI: 10.5530/ijpi.20260011Vol. 16, Issue 4 (2026)

    Background: This study focuses on the computational (in silico) analysis of 1H-phenothiazine derivatives to estimate their pharmacological potential, particularly as inhibitors of monoamine oxidase (PDB ID: 2BXR), an enz…

  10. Original ArticlePublished: 18 Aug 2026

    Vishal Kulkarni, Kavya Mattikatti, Manasa Desai, Darshan Randewadi, Nida Sirdesai, Sanatkumar Bharamu Nyamagoud, AHM Viswanatha Swamy

    pp. 1719-1724 · DOI: 10.5530/ijpi.20260176Vol. 16, Issue 4 (2026)

    Aim: To evaluate early changes in symptom-specific Health-Related Quality of Life (HRQoL) among Esophageal cancer patients receiving chemotherapy up to the second cycle and to assess demographic and treatment-related dif…