International Journal of Pharmaceutical Investigation
Volume 12, Issue 4
2022 · pp. 400–492 · 16 articles
- Volume
- 12
- Issue
- 4
- Year
- 2022
- Published
- 6 Oct 2022
- Pages
- 400–492
- Articles
- 16
- Sections
- 2
- ISSN
- 2230-9713
- Journal
- IJPI
In this issue
Review Article
Review ArticlePublished: 6 Oct 2022
Leena Rajathy Port Louis, Prithiviraj Nagarajan, Asokan Balakrishnan Ramajayam
pp. 400-402 · DOI: 10.5530/ijpi.2022.4.69Vol. 12, Issue 4 (2022)Animal experiments are routinely carried out worldwide either in educational setups or in research setups. Animal research can be basic or applied, where in the applied research the test compound/drug is tested in animal…
Review ArticlePublished: 6 Oct 2022
Vaibhav SU, Vedamurthy Joshi, Prakash Goudanvar, Soumik Banerjee, Vinay Prasad S
pp. 403-407 · DOI: 10.5530/ijpi.2022.4.70Vol. 12, Issue 4 (2022)The Office of combination products OCP, an agency to regulate the combination products under the US Food and Drug Administration (FDA) has released the final guidance on the combination products for its approval which is…
Review ArticlePublished: 6 Oct 2022
Gaurav Tiwari, Akanksha Chauhan, Pooja Sharma, Ruchi Tiwari
pp. 408-417 · DOI: 10.5530/ijpi.2022.4.71Vol. 12, Issue 4 (2022)Capra hircus (Goats) are a vital part of the livestock industry because of their ability to adapt to harsh conditions, making them ideal for landless and marginal farmers. The Capra hircus is one of the most prominent op…
Original Article
Original ArticlePublished: 6 Oct 2022
Kevizano Jacinta Zashumo, V Mathivanan, Hezinglila Grace, D Leelavathi
pp. 418-422 · DOI: 10.5530/ijpi.2022.4.72Vol. 12, Issue 4 (2022)Background: Obesity is a major problem that many individuals suffer presently. Using in silico Tools and Servers, we propose to build a novel chemical drug and validate its oral toxicity effect. Our strategy entails firs…
Original ArticlePublished: 6 Oct 2022
Anushya Sankar, Shanthi Periyasamy, Sownthariya Chandrabalan
pp. 423-429 · DOI: 10.5530/ijpi.2022.4.73Vol. 12, Issue 4 (2022)Background: Morinda umbellata L., commonly called as ‘Manjanatti Kodi’ in Tamilnadu, India, is a rare traditional medicinal plant. The study was aimed to investigate the antioxidant potentiality, phytochemical profiling …
Original ArticlePublished: 6 Oct 2022
Rameshor Singh Atom, Shaukat Ali M Shaikh, Kishorjit Maharabam, Rakhi Khunjamayum, Dini Ahanthem, Warjeet Singh Laitonjam, Raghumani Singh Ningthoujam, Amit Kunwar
pp. 430-437 · DOI: 10.5530/ijpi.2022.4.74Vol. 12, Issue 4 (2022)Bakground: Kaempferia parviflora (zingiberaceae family) rhizomes are used for various pharmacological applications. The present study is aimed for putative identification of phyto-constituents in the chloroform extract o…
Original ArticlePublished: 6 Oct 2022
Donthamsetty V Sowmya, Srirama Swarnalatha, Morusu Keerthana, Pothina Devi Guna Sireesha, Maruvajhala Vidyavathi
pp. 438-443 · DOI: 10.5530/ijpi.2022.4.75Vol. 12, Issue 4 (2022)Background: Liver is one of the most important human organs and is a sensitive target for chemicals that modulate biotransformation. The present study aimed to develop a polyherbal formulation in the form of both capsule…
Original ArticlePublished: 6 Oct 2022
N Raghavendra Babu, R Subhakar Raju, Narender Malothu, Yenumula Padmavathi
pp. 444-448 · DOI: 10.5530/ijpi.2022.4.76Vol. 12, Issue 4 (2022)Background: The largest infectious agent-related cause of death and the most common disease with a high contagiousness profile is tuberculosis. For the treatment of tuberculosis, various benzimidazole and quinazoline com…
Original ArticlePublished: 6 Oct 2022
Somesh Kumar Saxena, Om Prakash Agrawal, Ashish Pathak
pp. 449-454 · DOI: 10.5530/ijpi.2022.4.77Vol. 12, Issue 4 (2022)Background: Chroman-4-one, also known as 2,3-dihydro-1-benzopyran- 4-one, is a heterocyclic compound with a benzene nucleus fused to a 2,3-dihydro-g-pyranone ring. The synthesis of chroman-4-one derivatives is a very app…
Original ArticlePublished: 6 Oct 2022
Ram Lal Saini, Seema Parveen, Rajni Bais
pp. 455-461 · DOI: 10.5530/ijpi.2022.4.78Vol. 12, Issue 4 (2022)Background: This research was focused on the development of a quick, simple, precise, and cost-effective voltammetric method for quantifying dosulepin. Materials and Methods: The antidepressant drug (dosulepin) was asses…
Original ArticlePublished: 6 Oct 2022
PH Viramgama, CD Modi, DJ Patel, AB Chaudhary
pp. 462-469 · DOI: 10.5530/ijpi.2022.4.79Vol. 12, Issue 4 (2022)Background: Alcohol induced dose dumping is a noteworthy question in designing of modified release dosage forms and it led the marketed products withdrawal by regulatory agencies. Diltiazem HCl is a highly watersoluble d…
Original ArticlePublished: 6 Oct 2022
Rajashri Namdev Kausdikar, Manish S Kondawr, Fahim J Sayyad
pp. 470-474 · DOI: 10.5530/ijpi.2022.4.80Vol. 12, Issue 4 (2022)Background: Dry skin conditions’ primary and secondary infections can be treated by using mupirocin topically. By overcoming the disadvantages of ointments, creams, and lotions, the goal of the formulation of mupirocin e…
Original ArticlePublished: 6 Oct 2022
Sreejan Manna, Abdul Aziz, Sanchita Das, Manas Bhowmik
pp. 475-478 · DOI: 10.5530/ijpi.2022.4.81Vol. 12, Issue 4 (2022)Background: Glibenclamide is a second-generation sulfonylurea extensively associated with the therapy of diabetes mellitus. A sustained release of the drug in the gastrointestinal tract may aid in maintaining therapeutic…
Original ArticlePublished: 6 Oct 2022
Harini Narayanam, Archana Rajagopalan, Subramani Parasuraman, Parayil Varghese Christapher, Suresh V Chinni
pp. 479-482 · DOI: 10.5530/ijpi.2022.4.82Vol. 12, Issue 4 (2022)Background: Parkinson’s disease (PD) is one of the most common degenerative disorders of the ageing brain. Currently, there is no cure for PD and most of the available treatments only aim to reverse the dopamine deficien…
Original ArticlePublished: 6 Oct 2022
Afaf S Alwabli
pp. 483-488 · DOI: 10.5530/ijpi.2022.4.83Vol. 12, Issue 4 (2022)Background: Dengue virus is transmitted by the mosquito species Aedes aegypti and causes dengue fever. The single positive-stranded RNA virus of the family Flaviviridae belongs to the genus Flavivirus. There is four deng…
Original ArticlePublished: 6 Oct 2022
Pradeep Battula, Bhupalam Pradeep Kumar
pp. 489-492 · DOI: 10.5530/ijpi.2022.4.84Vol. 12, Issue 4 (2022)Background: When two antibiotics are used at the simultaneously, they interact. The interaction could be either synergistic or antagonistic. However, an antagonistic combination may halt the action of another antibiotic,…