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International Journal of Pharmaceutical Investigation

Volume 17, Issue 1(Current Issue)

2027 · pp. 1–503 · 47 articles

Volume
17
Issue
1
Year
2027
Published
2 Nov 2026
Pages
1–503
Articles
47
Sections
3
ISSN
2230-9713
Journal
IJPI

In this issue

21–40 of 47

Original Article(continued)

  1. Original ArticlePublished: 16 Oct 2026

    Ramalingam Gomathi, Thirupambaram Nataraja Sundaram Uma Maheswari, Shanmugam Rajesh Kumar

    pp. 232-237 · DOI: 10.5530/ijpi.20270007Vol. 17, Issue 1 (2027)

    Background: Chronic inflammation and oxidative stress lead to tissue damage, resulting in heightened interest in plant-based therapeutics with low toxicity. Sesame and raspberry contain bioactive compounds that are both …

  2. Original ArticlePublished: 16 Oct 2026

    Sonika Shrivastav, Kamal Singh Rathore, Dinesh Kumar Yadav, Phool Chandra, Arvind Raghav, Neetu Sachan

    pp. 238-248 · DOI: 10.5530/ijpi.20270015Vol. 17, Issue 1 (2027)

    Background: Major depressive disorder is a heterogeneous disease that primarily contributes to global disability. In this condition, individuals often experience disturbances in sleep patterns and psychomotor functions, …

  3. Original ArticlePublished: 16 Oct 2026

    Reddy Prasad Chowdareddy, Thirunavukkarasu Jayaraman, Afzal Khan AK, Mohanakrishna Ghanta, Bibi Umeza

    pp. 249-255 · DOI: 10.5530/ijpi.20270024Vol. 17, Issue 1 (2027)

    Objectives: Pomegranate (Punica granatum) is a well-known source of bioactive phytochemicals, particularly punicalagin, which contributes to its antioxidant, anti-inflammatory, and antimicrobial properties. Materials and…

  4. Original ArticlePublished: 16 Oct 2026

    Jitendra Kantilal Chordiya, Ujashkumar Shah, Nidhi Shah

    pp. 256-268 · DOI: 10.5530/ijpi.20270050Vol. 17, Issue 1 (2027)

    Background: The Multi unit-controlled release dosage forms is a drug delivery system offering advantage over traditional monolithic controlled release system in achieving persistent and predictable drug delivery. Multipl…

  5. Original ArticlePublished: 16 Oct 2026

    Jigneshkumar Varu, Pradeep Shahajirao Shindhe, Ramesh Shivappa Killedar, Aniket Ughade

    pp. 269-275 · DOI: 10.5530/ijpi.20270060Vol. 17, Issue 1 (2027)

    Introduction: In Ayurveda, Allium sativum (Lashuna) has been described in great detail as a Medhya medication that may improve cognitive function. The current study used molecular docking and in silico network pharmacolo…

  6. Original ArticlePublished: 16 Oct 2026

    Shalam Mohamed Hussain, Nayef Almutairi, Fahad Alrakaf, Mohammed Aljameli

    pp. 276-282 · DOI: 10.5530/ijpi.20270064Vol. 17, Issue 1 (2027)

    Background: Alzheimer’s disease affecting about 18 million people world-wide. The socio-economic burden on world-economies costing more than 172 billion US $ annually for the US alone. Objectives: To prepare aqueous extr…

  7. Original ArticlePublished: 16 Oct 2026

    Abhishek Pete Nagaraj, Purushotham Karadigere Nagaraju

    pp. 283-291 · DOI: 10.5530/ijpi.20270083Vol. 17, Issue 1 (2027)

    Background: Epilepsy is a chronic neurological disorder characterized by recurrent seizures caused by abnormal electrical activity in the brain. The development of novel anticonvulsant agents with improved efficacy and s…

  8. Original ArticlePublished: 16 Oct 2026

    Tuba Türkoğlu, Semra Türkoğlu

    pp. 292-299 · DOI: 10.5530/ijpi.20270108Vol. 17, Issue 1 (2027)

    Background: Verbascum diversifolium, an endemic medicinal plant native to Türkiye, is recognized for its potential therapeutic and economic value. This study aimed to evaluate the antimicrobial, antioxidant, total phenol…

  9. Original ArticlePublished: 16 Oct 2026

    Yuanchao Kang, Shizhe Chen, Yanwen Hao, Yan Lin

    pp. 300-309 · DOI: 10.5530/ijpi.20270131Vol. 17, Issue 1 (2027)

    Background: Adverse Drug Reactions (ADRs) severely affect clinical medication safety, and the Pareto principle is widely applied to identify key risk factors in pharmacovigilance. Systematic retrospective analysis of hos…

  10. Original ArticlePublished: 16 Oct 2026

    Mitali Milind Bodhankar, Shrushti Soitkar, Snehal Shrivastav, Shubham Gupta, Pranali Band

    pp. 310-321 · DOI: 10.5530/ijpi.20270132Vol. 17, Issue 1 (2027)

    Background/Objectives: Cutaneous candidiasis remains a significant clinical challenge, particularly in warm, moist body regions and immunocompromised individuals. This study focuses on the development and evaluation of a…

  11. Original ArticlePublished: 16 Oct 2026

    Hema Barti, Krishana Kumar Sharma

    pp. 322-328 · DOI: 10.5530/ijpi.20270134Vol. 17, Issue 1 (2027)

    Background: Hepatocellular Carcinoma (HCC) is a common and highly aggressive form of cancer worldwide. Oxidative stress is closely associated with the development and progression of HCC. An excessive increase in Reactive…

  12. Original ArticlePublished: 16 Oct 2026

    Priyanka Shah, Riya Patel, Shreeraj Shah

    pp. 329-337 · DOI: 10.5530/ijpi.20270173Vol. 17, Issue 1 (2027)

    Background: Stress management remains a significant therapeutic challenge, necessitating the development of novel delivery systems that enhance patient adherence. This research presents the formulation and characterizati…

  13. Original ArticlePublished: 16 Oct 2026

    Ladi Alik Kumar, Gurudutta Pattnaik, Himansu Bhusan Samal, K Naga Jogayya, Chandra Sekhar Patro, Gopal Krishna Padhy

    pp. 338-344 · DOI: 10.5530/ijpi.20270206Vol. 17, Issue 1 (2027)

    Background: Metronidazole is a commonly prescribed nitroimidazole antibiotic for Bacterial Vaginosis (BV), rosacea, periodontal infections, and other anaerobic or protozoal infections. However, conventional topical dosag…

  14. Original ArticlePublished: 16 Oct 2026

    Yan-Ling Wu, Cui Zhen-Yu

    pp. 345-349 · DOI: 10.5530/ijpi.20270219Vol. 17, Issue 1 (2027)

    Background: As an important discipline in medicine and pharmacy, pharmacology teaching needs constant improvement to adapt to social demands and technological developments. This study proposes suggestions based on “speci…

  15. Original ArticlePublished: 16 Oct 2026

    Amani Alharthi

    pp. 350-361 · DOI: 10.5530/ijpi.20270225Vol. 17, Issue 1 (2027)

    Background: Lung carcinoma is one of the most important health problems in the world and there is a need to develop effective and less toxic therapeutic agents. Computational drug discovery is an efficient approach for d…

  16. Original ArticlePublished: 16 Oct 2026

    Chun-Mei Wang, Bo Shen, Chen-Yan Xu, Jing Zhang, Lu Yang, Ren-Zheng Huang, Hua Chen

    pp. 362-372 · DOI: 10.5530/ijpi.20270229Vol. 17, Issue 1 (2027)

    Background: Dihydroartemisinin (DHA), a well-established antimalarial agent has been increasingly recognized for its antiviral and antitumor effects across multiple diseases. However, the potential effects of DHA on Non-…

  17. Original ArticlePublished: 16 Oct 2026

    Varsha Mugundhan, Priyangha Ponmudi Thangavel

    pp. 373-380 · DOI: 10.5530/ijpi.20270230Vol. 17, Issue 1 (2027)

    Background: Artificial sweeteners are widely used as non-cariogenic alternatives to dietary sugars, and beyond their sweetening properties, certain sweeteners have demonstrated antimicrobial activity, suggesting potentia…

  18. Original ArticlePublished: 1 Jan 2026

    Pranay Kumar Ravula, Lakshmi Manogna Parupudi, Pravalika Pottigari, Jahnavi Bandla

    pp. 381-400 · DOI: 10.5530/ijpi.20270240Vol. 17, Issue 1 (2027)

    Background: The widespread availability of branded and generic antidiabetic tablet formulations has increased the need for rapid, reliable, and cost-effective analytical methods to ensure their authenticity and quality. …

  19. Original ArticlePublished: 16 Oct 2026

    Vipul Kumar, Vaibhav Rastogi

    pp. 401-429 · DOI: 10.5530/ijpi.20270253Vol. 17, Issue 1 (2027)

    Background: Amisulpride, a Biopharmaceutics Classification System (BCS) Class II antipsychotic drug, exhibits limited aqueous solubility, resulting in poor dissolution and suboptimal oral bioavailability. Self-Emulsifyin…

  20. Original ArticlePublished: 16 Oct 2026

    Pranaya Peram, Geetha Karra, Pravalika Patlolla, V Uma Maheswara Rao

    pp. 430-439 · DOI: 10.5530/ijpi.20270241Vol. 17, Issue 1 (2027)

    Background: Chronic wounds, including diabetic ulcers, pressure ulcers, and burn injuries, are characterized by persistent infection, prolonged inflammation, and impaired tissue regeneration, making them difficult to tre…