Effect of Local Application of Curcumin and Ornidazole Gel in Chronic Periodontitis Patients

  • P. L. Ravishankar Department of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India
  • Y. Pradeep Kumar Department of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India
  • E. N. Anila Department of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India
  • Priyankar Chakraborty Department of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India
  • Maharshi Malakar Department of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India
  • R. Mahalakshmi Department of Periodontics, SRM Kattankulathur Dental College, Kanchipuram, Tamil Nadu, India
Keywords: Curcumin, Local drug delivery, Ornidazole

Abstract

Objective: The objective of this study is to evaluate the comparative effect of curcumin and ornidazole in treating chronic periodontitis. Materials and Methods: Twenty individuals of both sexes aged between 27 and 53 years diagnosed with chronic periodontitis and having pocket depths >5 mm bilaterally were selected for this study, in a split‑mouth design. Examination of plaque index, probing pocket depth and clinical attachment level was measured for each patient. The patients received a complete prophylaxis including scaling and root planing after which, both test gels were injected into the two experimental sites chosen, that had probing depth (PD) >5 mm and were located in symmetric quadrants. Pocket PD, clinical attachment loss and plaque index were recorded at days 0 and 30. Results: At 1‑month evaluation, curcumin group showed a significant decrease in pocket PD, plaque index and clinical attachment loss when compared to the ornidazole group. Conclusion: The results show a more favorable outcome with curcumin than ornidazole gel, thus curcumin can be used as an adjunct to nonsurgical periodontal therapy.

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Commercially available curcumin and ornidazole
Published
2018-04-06
How to Cite
1.
Ravishankar PL, Kumar YP, Anila EN, Chakraborty P, Malakar M, Mahalakshmi R. Effect of Local Application of Curcumin and Ornidazole Gel in Chronic Periodontitis Patients. ijpi [Internet]. 6Apr.2018 [cited 31Jul.2021];7(4):188-92. Available from: https://www.jpionline.org/index.php/ijpi/article/view/277