Standardization of Kirāmpu kutinīr Decoction and Extract Granules using Pharmacognostic, Physicochemical and HPTLC Studies

Shree Devi Munusamy Sampangiramulu; Brindha Sundaramoorthy; Achintya Kumar Mandal; Vinayak Soman; Sunil Kumar Koppala Narayana; Shakila Ramachandran; Sathiyarajeswaran Parameswaran; Kiruthiga Ganesan

doi:10.5530/ijpi.2021.4.65

Shree Devi Munusamy Sampangiramulu Department of Pharmacy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA
Brindha Sundaramoorthy Department of Pharmacognosy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
Achintya Kumar Mandal Department of Chemistry, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
Vinayak Soman Department of Pharmacy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
Sunil Kumar Koppala Narayana Department of Pharmacognosy, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
Shakila Ramachandran Department of Chemistry, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
Sathiyarajeswaran Parameswaran Director I/c, Siddha Central Research Institute, Chennai, Tamil Nadu, INDIA.
Kiruthiga Ganesan Central Council for Research in Siddha, Chennai, Tamil Nadu, INDIA.

DOI: https://doi.org/10.5530/ijpi.2021.4.65

Keywords: Herbal medicine, Polyherbal formulation, Respiratory infection, Siddha COVID care, Quality control, Vector-borne diseases

Abstract

Introduction: Siddha being one of the ancient systems of medicine, has been counted on by most of the population during the outbreak of pandemics in recent times. The decoctions like nilavempu kutinir and kapacura kutinir have been authorized for prescription for conditions like dengue, Covid-19 etc. Kirampu kutinir (KK) is one such decoctions which has been found efficacious in Covid patients with respiratory tract infections. The current study is aimed at standardizing KK curnam and two of its dosage forms like Kutinir and extract granule employing pharmacognostic and chemical analyses. Methods: Kirampu kutintr (KK) and Kirampu kutinir extract granules (KEG) were analysed for pharmacopoeial standards following standard procedures. Results: The macroscopy and powder microscopy correlated with standards and matched with their characters. Both HPTLC photo documentation and densitometric scan revealed that the KEG comprises of the said ingredients. It also divulges that KEG and KK are of same bands and same pattern. Conclusion: The reported results will be supportive for standardization and future studies of KK.

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