International Journal of Pharmaceutical Investigation

ORIGINAL RESEARCH ARTICLE
Year
: 2017  |  Volume : 7  |  Issue : 3  |  Page : 111--118

Gingivitis and plaque prevention using three commercially available dentifrices: A comparative clinical and microbiological randomized control parallel study


Ramprasad Reddy1, Rajababu Palaparthy2, Satyanarayana Durvasula2, Pradeep Koppolu3, Essam Elkhatat3, Khaled Ali Rajab Assiri3, Al Sulaiman Abdulrahman Saad A3 
1 Department of Periodontics, Aditya Dental College, Beed, Maharashtra, India
2 Department of Periodontics, Kamineni Institute of Dental Sciences, Nalgonda, Telangana, India
3 Department of Preventive Dental Sciences, Al-Farabi Colleges, Riyadh, Kingdom of Saudi Arabia

Correspondence Address:
Ramprasad Reddy
Department of Periodontics, Aditya Dental College, Beed, Maharashtra
India

Aim: The aim of the study was to compare the clinical and microbiological efficacy of Group I-delmopinol dentifrice, Group II-chlorhexidine, and Group III-triclosan-containing regularly used control dentifrice on plaque formation and gingivitis. Materials and Methods: A total of 45 healthy volunteer students fulfilling the inclusion criteria are recruited for this randomized control parallel study. All the individuals were randomly assigned into 3 groups depending on the dentifrice prescribed. After the selection of individuals, thorough scaling and polishing were performed for all the individuals, and in a 4 days' washout period, they were refrained from regular oral hygiene maintenance and 0.9% NaCl (normal saline) rinse was prescribed to obtain plaque regrowth. Microbiological morphotypes were assessed using darkfield microscope. Statistical Analysis: The data were analyzed using the SPSS-software 19.00 program. The intragroup comparison of clinical parameters was done using Kruskal–Wallis ANOVA test, and intergroup comparison was done by Mann–Whitney U-test. The intragroup comparison of clinical parameters including modified staining index, the supragingival microbiota such as cocci, bacilli, and spirochetes scores was done at various study intervals using one-way ANOVA, and intergroup comparison was done using Tukey's multiple post hoc test. Results: The results showed that statistically significant correlation between Group II and Group III at 15 and 30 days and between Group I and Group II at 30 days with cocci and bacilli but not spirochetes. Conclusion: Group II showed better plaque and gingivitis reduction compared to other active groups. To validate the results of the present study, further long-term studies with larger sample size and evaluation using known and proven study designs on gingivitis patients are needed.


How to cite this article:
Reddy R, Palaparthy R, Durvasula S, Koppolu P, Elkhatat E, Assiri KA, Abdulrahman Saad A A. Gingivitis and plaque prevention using three commercially available dentifrices: A comparative clinical and microbiological randomized control parallel study.Int J Pharma Investig 2017;7:111-118


How to cite this URL:
Reddy R, Palaparthy R, Durvasula S, Koppolu P, Elkhatat E, Assiri KA, Abdulrahman Saad A A. Gingivitis and plaque prevention using three commercially available dentifrices: A comparative clinical and microbiological randomized control parallel study. Int J Pharma Investig [serial online] 2017 [cited 2017 Dec 14 ];7:111-118
Available from: http://www.jpionline.org/article.asp?issn=2230-973X;year=2017;volume=7;issue=3;spage=111;epage=118;aulast=Reddy;type=0