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1Challenges to improve the biopharmaceutical properties of poorly water-soluble drugs and the application of the solid dispersion technology
Gabriela Tambosi,Paola Felippi Coelho,Soares Luciano,Iára Cristina Schmücker Lenschow,Melissa Zétola,Hellen Karine Stulzer,Bianca Ramos Pezzini
Matéria (Rio de Janeiro).2018;23(4)
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2Novel N-thioamide analogues of pyrazolylpyrimidine based piperazine: Design, synthesis, characterization, in-silico molecular docking study and biological evaluation
Mayur K. Vekariya,Dhaval B. Patel,Pranav A. Pandya,Rajesh H. Vekariya,Prapti U. Shah,Dhanji P. Rajani,Nisha K. Shah
Journal of Molecular Structure.2019;1175(4)551
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3Novel instantly-soluble transmucosal matrix (ISTM) using dual mechanism solubilizer for sublingual and nasal delivery of dapoxetine hydrochloride: In-vitro / in-vivo evaluation
Shahinaze A. Fouad,Rehab N. Shamma,Emad B. Basalious,Mohamed A. El-Nabarawi,Saadia A. Tayel
International Journal of Pharmaceutics.2016;505(1-2)212
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4Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity
Hongxing Wang,Qigui Li,Sean Reyes,Jing Zhang,Lisa Xie,Victor Melendez,Mark Hickman,Michael P. Kozar
Malaria Research and Treatment.2013;2013(1-2)1
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5Palmitoylethanolamide in the Treatment of Failed Back Surgery Syndrome
Antonella Paladini,Giustino Varrassi,Giuseppe Bentivegna,Sandro Carletti,Alba Piroli,Stefano Coaccioli
Pain Research and Treatment.2017;2017(1-2)1
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6Precipitation of resveratrol-isoniazid and resveratrol-nicotinamide cocrystals by gas antisolvent
Alcidênio S. Pessoa,Gean Pablo S. Aguiar,J. Vladimir Oliveira,Adailton J. Bortoluzzi,Amarilis Paulino,Marcelo Lanza
The Journal of Supercritical Fluids.2019;145(1-2)93
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7Precipitation of resveratrol-isoniazid and resveratrol-nicotinamide cocrystals by gas antisolvent
Stephen D. Skaper
The Journal of Supercritical Fluids.2019;245(1-2)119
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8Palmitoylethanolamide, a naturally occurring disease-modifying agent in neuropathic pain
Stephen D. Skaper,Laura Facci,Mariella Fusco,Maria Federica della Valle,Morena Zusso,Barbara Costa,Pietro Giusti
Inflammopharmacology.2014;22(2)79
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9Preparation, characterization, and pharmacokinetics in swine of a florfenicol enteric formulation prepared using hot-melt extrusion technology
Y. Xu,X. Wen,X. Feng,Z. Liang,X. Ye,H. Nie,X. Liao,J. Li,Y. Zeng,S. Tang,J. He
Journal of Veterinary Pharmacology and Therapeutics.2018;41(4)572
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10Micronized palmitoylethanolamide reduces joint pain and glial cell activation
Maria Lavinia Bartolucci,Ida Marini,Francesco Bortolotti,Daniela Impellizzeri,Rosanna Di Paola,Giuseppe Bruschetta,Rosalia Crupi,Marco Portelli,Angela Militi,Giacomo Oteri,Emanuela Esposito,Salvatore Cuzzocrea
Inflammation Research.2018;67(10)891
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11Nanoemulsions in Translational Research—Opportunities and Challenges in Targeted Cancer Therapy
Srinivas Ganta,Meghna Talekar,Amit Singh,Timothy P. Coleman,Mansoor M. Amiji
AAPS PharmSciTech.2014;15(3)694
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12Dual-stimuli responsive injectable microgel/solid drug nanoparticle nanocomposites for release of poorly soluble drugs
Adam R. Town,Marco Giardiello,Rohan Gurjar,Marco Siccardi,Michael E. Briggs,Riaz Akhtar,Tom O. McDonald
Nanoscale.2017;9(19)6302
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13Coupling 3D printing with hot-melt extrusion to produce controlled-release tablets
Jiaxiang Zhang,Xin Feng,Hemlata Patil,Roshan V. Tiwari,Michael A. Repka
International Journal of Pharmaceutics.2017;519(1-2)186
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14Selection of effective cocrystals former for dissolution rate improvement of active pharmaceutical ingredients based on lipoaffinity index
Piotr Cysewski,Maciej Przybylek
European Journal of Pharmaceutical Sciences.2017;107(1-2)87
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15Optimizing nanomedicine pharmacokinetics using physiologically based pharmacokinetics modelling
Darren Michael Moss,Marco Siccardi
British Journal of Pharmacology.2014;171(17)3963
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16Co-Amorphous Solid Dispersions for Solubility and Absorption Improvement of Drugs: Composition, Preparation, Characterization and Formulations for Oral Delivery
Anna Karagianni,Kyriakos Kachrimanis,Ioannis Nikolakakis
Pharmaceutics.2018;10(3)98
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17Development and evaluation of pharmaceutical 3D printability for hot melt extruded cellulose-based filaments
Jiaxiang Zhang,Pengchong Xu,Anh Q. Vo,Suresh Bandari,Fengyuan Yang,Thomas Durig,Michael A. Repka
Journal of Drug Delivery Science and Technology.2019;52(3)292
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18Study of phase equilibria and the physicochemical properties of selected pharmaceuticals
Aneta Pobudkowska,Barbara A. Jurkowska,Maciej A. Wiatrowski
Fluid Phase Equilibria.2015;406(3)209
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19Towards a rational design of solid drug nanoparticles with optimised pharmacological properties
Marco Siccardi,Phillip Martin,Darren Smith,Paul Curley,Tom McDonald,Marco Giardiello,Neill Liptrott,Steve Rannard,Andrew Owen
Journal of Interdisciplinary Nanomedicine.2016;1(3)110
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20Self dispersing mixed micelles forming systems for enhanced dissolution and intestinal permeability of hydrochlorothiazide
Amal A. Sultan,Sanaa A. El-Gizawy,Mohamed A. Osman,Gamal M. El Maghraby
Colloids and Surfaces B: Biointerfaces.2017;149(3)206
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21The role of nanoparticles in the improvement of systemic anticancer drug delivery
Lauren D Field,Okhil K Nag,Ajmeeta Sangtani,Kelly E Burns,James B Delehanty
Therapeutic Delivery.2018;9(7)527
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22Cocrystals of Leflunomide: Design, Structural, and Physicochemical Evaluation
Joseph Cadden,Wim T. Klooster,Simon J. Coles,Srinivasulu Aitipamula
Crystal Growth & Design.2019;9(7)527
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23Co-micellization behavior of triblock copolymers in the presence of hydrophobic drug molecules: A simulation study
Ammu Prhashanna,Wee Kian Tan,Saif A. Khan,Shing Bor Chen
Colloids and Surfaces B: Biointerfaces.2016;148(7)299
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24Effect of semicrystalline polymers on self-emulsifying solid dispersions of nateglinide: in vitro and in vivo evaluation
Ranjit Prasad Swain,Bharat Bhusan Subudhi
Drug Development and Industrial Pharmacy.2018;44(1)56
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25Polyamidoamine Dendrimers for Enhanced Solubility of Small Molecules and Other Desirable Properties for Site Specific Delivery: Insights from Experimental and Computational Studies
Daniel Shadrack,Hulda Swai,Joan Munissi,Egid Mubofu,Stephen Nyandoro
Molecules.2018;23(6)1419
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26Self-assembled micellar clusters based on Triton-X-family surfactants for enhanced solubilization, encapsulation, proteins permeability control, and anticancer drug delivery
Alexey V. Solomonov,Yuriy S. Marfin,Evgeniy V. Rumyantsev,Elena Ragozin,Talia Shekhter Zahavi,Gary Gellerman,Alexander B. Tesler,Falk Muench,Akiko Kumagai,Atsushi Miyawaki
Materials Science and Engineering: C.2019;99(6)794
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27Nanodispersions of beta-carotene: effects on antioxidant enzymes and cytotoxic properties
Felipe Rocha,Letícia Yumi Sugahara,Fernanda Vitória Leimann,Sara Marchesan de Oliveira,Evelyne da Silva Brum,Ricardo Costa Calhelha,Maria Filomena Barreiro,Isabel C. F. R. Ferreira,Rafael Porto Ineu,Odinei Hess Gonçalves
Food & Function.2018;9(7)3698
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28Imidazolium Ionic Liquid Helps to Disperse Fullerenes in Water
Eudes Eterno Fileti,Vitaly V. Chaban
The Journal of Physical Chemistry Letters.2014;5(11)1795
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29Amorphous Solid Dispersions: Utilization and Challenges in Drug Discovery and Development
Yan He,Chris Ho
Journal of Pharmaceutical Sciences.2015;104(10)3237
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30Melt-spun bioactive sutures containing nanohybrids for local delivery of anti-inflammatory drugs
Ovidio Catanzano,Stefano Acierno,Pietro Russo,Mariarosaria Cervasio,Marialaura Del Basso De Caro,Adele Bolognese,Gilberto Sammartino,Luigi Califano,Gaetano Marenzi,Antonio Calignano,Domenico Acierno,Fabiana Quaglia
Materials Science and Engineering: C.2014;43(10)300
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31Formulation and characterization study of itraconazole-loaded microparticles
Lorena Segale,Lorella Giovannelli,Paolo Mannina,Franco Pattarino
Pharmaceutical Development and Technology.2015;20(2)153
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32Effect of API-Polymer Miscibility and Interaction on the Stabilization of Amorphous Solid Dispersion: A Molecular Simulation Study
Yin Yani,Parijat Kanaujia,Pui Shan Chow,Reginald B. H. Tan
Industrial & Engineering Chemistry Research.2017;56(44)12698
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33Revealing facts behind spray dried solid dispersion technology used for solubility enhancement
Bhavesh B. Patel,Jayvadan K. Patel,Subhashis Chakraborty,Dali Shukla
Saudi Pharmaceutical Journal.2015;23(4)352
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34Enhancing solubility of poorly aqueous soluble drugs: critical appraisal of techniques
Dilpreet Singh,Neena Bedi,Ashok K. Tiwary
Journal of Pharmaceutical Investigation.2018;48(5)509
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35Solid-state, triboelectrostatic and dissolution characteristics of spray-dried piroxicam-glucosamine solid dispersions
Adeola O. Adebisi,Waseem Kaialy,Tariq Hussain,Hiba Al-Hamidi,Ali Nokhodchi,Barbara R. Conway,Kofi Asare-Addo
Colloids and Surfaces B: Biointerfaces.2016;146(5)841
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36Aqueous injection of quercetin: An approach for confirmation of its direct in vivo cardiovascular effects
Elena Piera Porcu,Massimo Cossu,Giovanna Rassu,Paolo Giunchedi,Guido Cerri,Jana Pourová,Iveta Najmanová,Thomas Migkos,Veronika Pilarová,Lucie Nováková,Premysl Mladenka,Elisabetta Gavini
International Journal of Pharmaceutics.2018;541(1-2)224
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37A Comparative Solubility Enhancement Study of Cefixime Trihydrate Using Different Dispersion Techniques
Rana M. Obaidat,Mai Khanfar,Rand Ghanma
AAPS PharmSciTech.2019;20(5)224
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38Toward Developing a Predictive Approach To Assess Electron Beam Instability during Transmission Electron Microscopy of Drug Molecules
Mark S’ari,Helen Blade,Rik Brydson,Stephen D. Cosgrove,Nicole Hondow,Leslie P. Hughes,Andy Brown
Molecular Pharmaceutics.2018;15(11)5114
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39Translation of combination nanodrugs into nanomedicines: lessons learned and future outlook
Qingxin Mu,Jesse Yu,Lisa A. McConnachie,John C. Kraft,Yu Gao,Gaurav K. Gulati,Rodney J. Y. Ho
Journal of Drug Targeting.2018;26(5-6)435
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40Surface-Modification of Carbonate Apatite Nanoparticles Enhances Delivery and Cytotoxicity of Gemcitabine and Anastrozole in Breast Cancer Cells
Qingxin Mu,Jesse Yu,Lisa A. McConnachie,John C. Kraft,Yu Gao,Gaurav K. Gulati,Rodney J. Y. Ho
Pharmaceutics.2017;9(4)21
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41Development of a gum base formulation for nystatin; a new drug delivery approach for treatment of oral candidiasis
Nasim Samiei,Elmira Olyaie,Sara Saberi,Mohammad Esmaeil Zolfaghari
Journal of Drug Delivery Science and Technology.2018;48(4)59
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42Advanced Pharmaceutical Applications of Hot-Melt Extrusion Coupled with Fused Deposition Modelling (FDM) 3D Printing for Personalised Drug Delivery
Deck Tan,Mohammed Maniruzzaman,Ali Nokhodchi
Pharmaceutics.2018;10(4)203
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43Relative Contributions of Solubility and Mobility to the Stability of Amorphous Solid Dispersions of Poorly Soluble Drugs: A Molecular Dynamics Simulation Study
Michael Brunsteiner,Johannes Khinast,Amrit Paudel
Pharmaceutics.2018;10(3)101
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44A Menthol-Based Solid Dispersion Technique for Enhanced Solubility and Dissolution of Sulfamethoxazole from an Oral Tablet Matrix
Bibi F. Choonara,Yahya E. Choonara,Pradeep Kumar,Lisa C. du Toit,Lomas K. Tomar,Charu Tyagi,Viness Pillay
AAPS PharmSciTech.2015;16(4)771
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45Aerosil as a novel co-crystal co-former for improving the dissolution rate of hydrochlorothiazide
Sanaa A. El-Gizawy,Mohamed A. Osman,Mona F. Arafa,Gamal M. El Maghraby
International Journal of Pharmaceutics.2015;478(2)773
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