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REVIEW ARTICLE
Year : 2012  |  Volume : 2  |  Issue : 1  |  Page : 2-11

Drug delivery systems: An updated review


1 Department of Pharmaceutics, Pranveer Singh Institute of Technology, Kanpur, Uttar Pradesh, India
2 Department of Pharmaceutics, Jaipur National University, Jagatpura, Jaipur, Rajasthan, India
3 Mankind Research Centre, Manesar, Gurgaon, India
4 Department of Pharmaceutics, SVKM's Narsee Monjee Institute of Management Studies (NMIMS), School of Pharmacy and Technology Management, Dhule, Maharashtra, India

Correspondence Address:
Gaurav Tiwari
Department of Pharmaceutics, Jaipur National University, Jagatpura, Jaipur, Rajasthan
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2230-973X.96920

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Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance. These routes provide promising alternatives to parenteral drug delivery particularly for peptide and protein therapeutics. For this purpose, several drug delivery systems have been formulated and are being investigated for nasal and pulmonary delivery. These include liposomes, proliposomes, microspheres, gels, prodrugs, cyclodextrins, among others. Nanoparticles composed of biodegradable polymers show assurance in fulfilling the stringent requirements placed on these delivery systems, such as ability to be transferred into an aerosol, stability against forces generated during aerosolization, biocompatibility, targeting of specific sites or cell populations in the lung, release of the drug in a predetermined manner, and degradation within an acceptable period of time.


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